Thrombin generation in PNH patients treated sequentially with Eculizumab and Ravulizumab: a paired analysis [0.03%]
依库珠单抗和拉珠单抗序贯治疗PNH患者血栓弹力图分析：队列研究
Mario Biglietto,Rosaria Mormile,Martina Gherardini et al.
Mario Biglietto et al.
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired disorder characterized by complement-mediated hemolysis and a high thrombotic risk. The introduction of complement inhibitors has markedly reduced thromboembolic events. Eculizuma...
Impact of extended duration pharmacological thromboprophylaxis on venous thromboembolism after hip and knee arthroplasty and hip fracture surgery: a systematic review and meta-analysis of randomised controlled trials [0.03%]
延长药理学血栓预防对髋关节和膝关节置换术以及股骨骨折术后静脉血栓栓塞的影响：随机对照试验的系统评价和meta分析
Usha Gurunathan,Matthew Bright,Daniel Mullany et al.
Usha Gurunathan et al.
Clinical practice guidelines on the optimal thromboprophylaxis duration following total hip and knee arthroplasty (THA and TKA) and hip fracture surgery are inconsistent. The aim of this meta-analysis is to investigate the effect of pharmac...
Direct oral anticoagulants or warfarin in left ventricular thrombus: an updated systematic review and meta-analysis of randomized trials [0.03%]
直接口服抗凝剂与华法林在左心室血栓中的应用：随机试验的系统评价和meta分析更新
Eduardo Dan Itaya,Ursula Medeiros Araujo de Matos,Moana Divina da Silva Santiago et al.
Eduardo Dan Itaya et al.
Mattia Galli,Dominick J Angiolillo
Mattia Galli
Rethinking lead-in strategies: evaluation of full vs. reduced dose factor Xa inhibitors in acute VTE [0.03%]
重温引入策略：急性VTE患者使用全剂量与减量直接Xa抑制剂的评估
Natasha Jolakoski,Sarah Grazia,Clare Brewster et al.
Natasha Jolakoski et al.
Oral factor Xa inhibitors are preferred treatments for venous thromboembolism (VTE). While apixaban and rivaroxaban require an initial lead-in period, clinicians may reduce the period if patients have received prior therapeutic parenteral a...
VTE risk assessment in trauma patients: a comparative analysis of Caprini, Trauma Embolic Scoring System, and Greenfield Risk Assessment profile models in a single sample [0.03%]
创伤患者静脉血栓风险评估模型的比较研究：Caprini、Trauma_embolic_scoring_system和Greenfield模型在单一样本中的对比分析
Erin M Scott,Eddy C Rios,Robert D Guber et al.
Erin M Scott et al.
Several risk assessment models (RAMs) guide standardized prophylaxis to prevent venous thromboembolism (VTE) in trauma patients. The Caprini, Trauma Embolic Scoring System (TESS), and Greenfield Risk Assessment Profile (RAP) have been valid...
Prognostic outcome of intravenous thrombolysis with non-immunogenic staphylokinase in patients aged ≥ 60 years with acute ischemic stroke by THRIVE scale [0.03%]
THRIVE量表评估的急性缺血性卒中患者大剂量非免疫原性链激酶静脉溶栓疗效及安全性研究
Nikolay A Shamalov,Zhanna Yu Chefranova,Elena B Yarovaya et al.
Nikolay A Shamalov et al.
This study aimed to assess the prognostic value of the THRIVE scale in patients aged ≥ 60 years with acute ischemic stroke (AIS) after intravenous thrombolysis with the non-immunogenic staphylokinase compared with alteplase. The post-hoc a...
Sex differences among elderly ACS patients undergoing percutaneous coronary intervention receiving Ticagrelor 60 mg vs. 90 mg [0.03%]
替卡格雷60毫克与90毫克在经皮冠状动脉介入治疗的急性冠脉综合征老年患者中的性别差异研究
Raffaele Piccolo,Angelo Laino,Antonio Pio Vitale et al.
Raffaele Piccolo et al.
No sex-based data are available on the pharmacodynamic and pharmacokinetic profile of ticagrelor 60 mg twice daily as alternative to its standard dose during the early phase after acute coronary syndrome (ACS). This post-hoc study is a sex-...
Integrative transcriptomic analysis identifies an oxidative stress-associated diagnostic signature for myocardial infarction [0.03%]
整合转录组分析鉴定出与氧化应激相关的诊断标志物用于心肌梗死的检测
Yuan Zhang,Tianyu Liang,Yanting Wang
Yuan Zhang
Reactive oxygen species (ROS) play a pivotal role in myocardial infarction (MI), contributing to oxidative stress, inflammation, and tissue remodeling. However, ROS-related gene signatures with diagnostic and mechanistic relevance in MI rem...
Comment on "Unmasking the phospholipid-induced 'hook effect' and its implications-increasing phospholipid can also lead to a longer clotting time in coagulation assays" [0.03%]
关于“揭秘磷脂诱导的‘钩状效应’及其影响——增加磷脂同样可延长凝血试验中的凝固时间”的评论
S Dhanya Dedeepya,Vaishali Goel,Nivedita Nikhil Desai
S Dhanya Dedeepya