Effect of blueberry extract on energetic metabolism, levels of brain-derived neurotrophic factor, and Ca2+-ATPase activity in the hippocampus and cerebral cortex of rats submitted to ketamine-induced mania-like behavior [0.03%]
蓝莓提取物对氯胺酮致类躁狂大鼠海马和大脑皮质能量代谢、脑源性神经营养因子及Ca2+-ATP酶活性的影响
Luiza Spohr,Mayara Sandrielly Pereira Soares,Natália Pontes Bona et al.
Luiza Spohr et al.
Bipolar disorder (BD) is a psychiatric disease characterized by mood episodes. Blueberry is rich in bioactive compounds and shows excellent therapeutic potential against chronic diseases. The aim of this study was to evaluate the effects of...
EIF4A3-induced circCCNB1 (hsa_circ_0001495) promotes glioma progression by elevating CCND1 through interacting miR-516b-5p and HuR [0.03%]
EIF4A3诱导的circCCNB1（hsa_circ_0001495）通过与miR-516b-5p和HuR相互作用来提高CCND1促进胶质瘤进展
Xiaoli Li,Chengmou Wang,Guanghui Chen et al.
Xiaoli Li et al.
To explore the functions of circRNA cyclin B1 (circCCNB1) in glioma and its possible mechanisms. The expression of circCCNB1, eukaryotic translation initiation factor 4A3 (EIF4A3), cyclin D1 (CCND1) and miR-516b-5p was determined by qRT-PCR...
A kinetic scheme to examine the role of glial cells in the pathogenesis of Alzheimer's disease [0.03%]
一种动力学方案研究胶质细胞在阿尔茨海默病发病机制中的作用
R A Thuraisingham
R A Thuraisingham
Alzheimer's disease (AD) is a complex neurodegenerative disorder that leads to severe impairments in cognitive functions including memory and learning. An improved kinetic model is proposed here to understand the pathogenesis of AD in parti...
Knockdown of circ_0007290 alleviates oxygen-glucose deprivation-induced neuronal injury by regulating miR-496/PDCD4 axis [0.03%]
circ_0007290低表达通过调控miR-496/PDCD4轴缓解氧糖剥夺诱导的神经元损伤
Fengjuan Wang,Jie Liu,Dan Wang et al.
Fengjuan Wang et al.
Circular RNAs (circRNAs) are highly enriched in the brain and involved in many types of central nervous system pathologies. Herein, this study aimed to investigate the role and mechanism of circ_0007290 in ischemic stroke. The oxygen-glucos...
Sevoflurane represses the progression of glioma by the regulation of circ_0037655/miR-130a-5p/RPN2 axis [0.03%]
七氟醚通过circ_0037655/miR-130a-5p/RPN2轴调控抑制胶质瘤进展
Jinyou Zhu,Bin Xie,Guiming Huang et al.
Jinyou Zhu et al.
Sevoflurane (SEV) is a common anesthetic to inhibit glioma progression. The previous studies have indicated the molecular mechanisms of SEV function in glioma. The objective of this study was to explore the association of circ_00037655 with...
The brain neuropeptides and STAT3 mediate the inhibitory effect of 17-β Estradiol on central leptin resistance in young but not aged female high-fat diet mice [0.03%]
雌激素抑制年轻而非年老高脂喂食小鼠中枢瘦素抵抗的机制研究
Zeinab Farhadi,Mohammad Khaksari,Hossein Azizian et al.
Zeinab Farhadi et al.
Aging and menopause effect on body composition and energy balance. Estrogen (E2) plays an important role in body's metabolism. The aim of the present study was to determine changes in leptin function in young intact and ovariectomized (OVX)...
Mandeep Kaur,Saurabh Sharma
Mandeep Kaur
Stroke is the second leading cause of death after coronary heart disease in developed countries and is the greatest cause of disability and cognitive impairment. Risk factors for cognitive impairment and dementia after stroke are multifacto...
NMR based CSF metabolomics in tuberculous meningitis: correlation with clinical and MRI findings [0.03%]
结核性脑膜炎中基于NMR的脑脊液代谢组学研究及其与临床和MRI结果的相关性
Rashmi Parihar,Ruchi Shukla,Bikash Baishya et al.
Rashmi Parihar et al.
We report the potential role of 1H Nuclear Magnetic Resonance (NMR) based metabolomics in tuberculous meningitis (TBM). We also correlate the significant metabolites with clinical-radiological parameters. Forty-three patients with TBM were ...
The association of stem cell factor and soluble c-Kit (s-cKit) receptor serum concentrations with the severity and risk prediction of autism spectrum disorders [0.03%]
干细胞因子和可溶性c-Kit(s-cKit)受体的血清浓度与自闭症谱系障碍严重程度及风险预测的关系研究
Farhad Mashayekhi,Somayeh Shabani,Soheila Talesh Sasani et al.
Farhad Mashayekhi et al.
S tem cell factor (SCF) and its receptor (c-kit) signaling play important role in normal brain physiology including neurogenesis, synapse formation and spatial learning function of the hippocampal region of the brain. Autism spectrum disord...
Neuroprotective role of Diosgenin, a NGF stimulator, against Aβ (1-42) induced neurotoxicity in animal model of Alzheimer's disease [0.03%]
薯蓣皂素的神经保护作用：作为一种NGF刺激剂抵抗阿尔茨海默病动物模型中的Aβ（1-42）诱导的神经毒性
Swati Som,Justin Antony,SPalanisamy Dhanabal et al.
Swati Som et al.
Diosgenin is a neurosteroid derived from the plants and has been previously reported for its numerous health beneficial properties, such as anti-arrhythmic, hypolipidemic, and antiproliferative effects. Although several studies conducted ea...