A novel heterozygous variant in PANX1 causes primary infertility due to oocyte death [0.03%]
PANX1基因的新杂合变异通过引起卵母细胞死亡导致原发性不育
Juepu Zhou,Meng Wang,Juan Hu et al.
Juepu Zhou et al.
Purpose: Variants in the pannexin1 (PANX1) gene have been reported to be associated with oocyte death and recurrent in vitro fertilization failure. In this study, we performed genetic analysis in the patient with female i...
Increased expression of NLRP3 inflammasome components in granulosa cells and follicular fluid interleukin(IL)-1beta and IL-18 levels in fresh IVF/ICSI cycles in women with endometriosis [0.03%]
内异症患者新鲜IVF/ICSI周期中颗粒细胞NLRP3炎症小体成分表达增多及卵泡液白介素（IL）-1β和IL-18水平改变
Bruno M Fonseca,Beatriz Pinto,Lia Costa et al.
Bruno M Fonseca et al.
The inflammasomes are a family of recently described multi-protein cytoplasmic sensors that orchestrate the inflammatory response and participate in a variety of inflammatory conditions. We hypothesized that the activation of pyrin domain‑...
Comparison of DNA methylation profiles of human embryos cultured in either uninterrupted or interrupted incubators [0.03%]
在连续培养或间断培养孵育的人胚胎DNA甲基化谱的对比分析
Ling Zhu,Xi Zeng,Weiwei Liu et al.
Ling Zhu et al.
Purpose: We aimed to compare the DNA methylation profiles of human embryos cultured in uninterrupted or interrupted incubators. Methods: ...
PGT-A is associated with reduced cumulative live birth rate in first reported IVF stimulation cycles age ≤ 40: an analysis of 133,494 autologous cycles reported to SART CORS [0.03%]
PGT-A与≤40岁女性首次报道的IVF刺激周期中的累计活产率降低有关：对报告给SART CORS的133,494个自体周期的分析
Alexander Kucherov,Melissa Fazzari,Harry Lieman et al.
Alexander Kucherov et al.
Purpose: To evaluate the impact of preimplantation genetic testing for aneuploidy (PGT-A) on cumulative live birth rate (CLBR) in IVF cycles. Methods: ...
David F Albertini
David F Albertini
The diagnostic experience of women with fragile X-associated primary ovarian insufficiency (FXPOI) [0.03%]
脆性X相关原发卵巢功能不全(FXPOI)患者的诊断体验
Bonnie Poteet,Nadia Ali,Cecelia Bellcross et al.
Bonnie Poteet et al.
Purpose: The fragile X premutation occurs when there are 55-200 CGG repeats in the 5' UTR of the FMR1 gene. An estimated 1 in 148 women carry a premutation, with 20-30% of these individuals at risk for fragile X-associate...
Brooke Cherven,Erin Kelling,Rebecca Williamson Lewis et al.
Brooke Cherven et al.
Purpose: Cancer survivors with a history of gonadotoxic treatment are at risk for future infertility and reproductive concerns, including worry about infertility. The purpose of this study was to describe factors associat...
Chromosomal segregation analysis and HOST-based sperm selection in a complex reciprocal translocation carrier [0.03%]
染色体分离分析和基于HOST的精子选择在复杂相互易位携带者中的应用
Capucine Rossi,Jean-Pierre Siffroi,Léa Ruosso et al.
Capucine Rossi et al.
Introduction: Complex chromosomal rearrangements (CCRs) involve two or more chromosomes and at least three breakpoints. Due to their complexity, they are associated with a high number of unbalanced gametes, whose fertiliz...
Inspection depth of uterine lumen measured by transvaginal ultrasound is associated with the success of IVF: a prospective longitudinal cohort study in China [0.03%]
经阴道超声测量的子宫腔检查深度与IVF的成功率有关：中国前瞻性纵向队列研究
Na Zuo,Sitong Dong,Da Li et al.
Na Zuo et al.
Objective: To measure the inspection depth of uterine lumen by transvaginal ultrasound and assess the association between the inspection depth and pregnancy outcomes in IVF-ET. ...
Risk of thrombosis in women with cancer undergoing controlled ovarian hyperstimulation for fertility preservation [0.03%]
癌症女性控制性超排卵保存生育力的血栓风险
Valeria D Melo,Olivia Y Liseth,Walker M Schmidt et al.
Valeria D Melo et al.
Purpose: The study aims to evaluate the risk factors and incidence of thromboembolic events among adult women with cancer who underwent controlled ovarian hyperstimulation (COH) for fertility preservation. ...