Shortened vitrification and warming improve survival and accelerate meiotic resumption in human germinal vesicle oocytes compared with standard protocols [0.03%]
短化玻璃化冷冻和解冻可提高人类生发泡卵子的存活率并加速成熟启动(与标准方案相比)
Alessandro Bartolacci,Arianna Frezza,Sofia de Girolamo et al.
Alessandro Bartolacci et al.
Purpose: Do shortened vitrification and warming (S-V/W) protocols achieve similar survival rates and meiotic resumption compared with standard protocols in human germinal vesicle (GV) oocytes? ...
Comment on "Live birth after oocyte donation in women with Turner syndrome compared with other causes of premature ovarian insufficiency: a retrospective cohort study" [0.03%]
特纳综合征女性与其它早发性卵巢功能不全女性在接受卵子捐赠后的活产结果比较:一项回顾性队列研究的述评
Madhuri Tribhuvan,Shashikant N Phatke
Madhuri Tribhuvan
Restoration of spermatogenesis in a male with prolactinoma-induced hypogonadotropic hypogonadism using follitropin delta and recombinant choriogonadotropin alfa: a case report [0.03%]
使用曲普瑞林和人絨毛膜促性腺激素治疗泌乳素瘤所致继发性性腺功能减退症的男性患者生精功能恢复一例报告
Moises Abraham Adel Domínguez,Walter D Cardona Maya,Andrés Mora Topete
Moises Abraham Adel Domínguez
Background: Follitropin delta is a recombinant human follicle-stimulating hormone (FSH) produced in the human PER.C6 cell line, approved exclusively for controlled ovarian stimulation in women. Its unique glycosylation pr...
Prevention of recurrence of severe combined immunodeficiency through preimplantation genetic testing: a case study of a novel IL2RG variant and confirmed maternal somatic mosaicism in Thailand [0.03%]
通过植入前遗传学检测预防泰国一例新型IL2RG变异和母体嵌合体严重联合免疫缺陷的复发:病例报告
Rattanamon Koonthaweelab,Napadon Yaibuates,Pongpet Benjaponwattana et al.
Rattanamon Koonthaweelab et al.
Research question: Can preimplantation genetic testing for monogenic disorders (PGT-M) be effectively implemented to prevent recurrence of X-linked severe combined immunodeficiency (X-SCID) caused by a novel IL2RG variant...
MAFF promotes decidual stromal cell senescence by suppressing NRF2-mediated antioxidant responses in recurrent pregnancy loss [0.03%]
MAFF通过抑制NRF2介导的抗氧化反应促进复发性妊娠丢失中的蜕膜基质细胞衰老
Weihua He,Yue Jin,Lijun Yin et al.
Weihua He et al.
Objective: Recurrent pregnancy loss (RPL) affects approximately 1-5% of couples, yet its underlying causes remain poorly understood. Aberrant cellular senescence in the decidua has been implicated in pregnancy loss, but t...
The effect of embryo vitrification duration on frozen-thawed transfer outcomes: the key moderating role of age-a retrospective cohort study of 13,054 cycles [0.03%]
胚胎玻璃化的持续时间对冻融移植结局的影响及年龄的调节作用:一项关于13054个治疗周期的研究
Yongxuan Ji,Ying Zhang,Huanze Cao et al.
Yongxuan Ji et al.
Purpose: To investigate how embryo vitrification duration affects frozen-thawed transfer outcomes, focusing on the interaction between age (at transfer and at freezing) and storage time. ...
Report of two patients with variants in FOXL2 and KASH5 and review of gestational trophoblastic neoplasia after recurrent moles [0.03%]
FOXL2和KASH5变异患者的报告及重复性摩鳞后妊娠滋养细胞肿瘤的回顾分析
Ankur Saharan,Reda Hemida,Maude Lefebvre et al.
Ankur Saharan et al.
Purpose: To elucidate possible genetic etiology in two patients with recurrent hydatidiform moles (RHM). Methods: Whole exome sequencin...
Developmental trajectories from day 2 to day 3 refine ranking and selection of cleavage-stage embryos [0.03%]
从第2天到第3天的发育轨迹可优化分裂期胚胎的选择和排名
Wen-Jie Huo,Fei Peng,Chen Luo et al.
Wen-Jie Huo et al.
Purpose: To determine whether day 2 to day 3 developmental trajectories improve day 3 embryo ranking and selection compared with day 3 cell number alone, thereby offering better prognostic information for cleavage-stage e...
Use of a sperm FcR assay in intracytoplasmic sperm injection improves day 5 good quality blastocyst yield [0.03%]
精子FcR检测在胞浆内精子注射中的应用可提高第5天优质囊胚的产率
Rebecca Holmes,Nadir Ciray,Kristy Savage et al.
Rebecca Holmes et al.
Purpose: The Kinetix FcR binding assay results correlate to male fertility in intrauterine insemination. Kinetix measures temporal expression of a sperm Fc receptor as sperm capacitate and become fertile, which in healthy...
Extended embryo culture and cumulative live birth in patients with limited embryos [0.03%]
胚胎扩展培养及有限胚胎数患者的累积活产率
Huizi Jin,Wenju Peng,Jiejun Luo et al.
Huizi Jin et al.
Purpose: Among IVF/ICSI patients with only 2-4 Day 3 embryos, which embryo culture strategy is associated with the highest cumulative live birth rate (CLBR): cleavage-stage transfer, blastocyst-stage transfer, or a mixed ...