A comparison between the Felix™ electrophoretic system of sperm isolation and conventional density gradient centrifugation: a multicentre analysis [0.03%]
Felix™精子分离电泳系统与常规密度梯度离心法的比较:多中心分析
Farnaz Shapouri,Tara Mahendran,Mirudhubashini Govindarajan et al.
Farnaz Shapouri et al.
Purpose: Developing optimized techniques for the isolation of human spermatozoa possessing low levels of DNA damage is an important objective for the ART industry. The purpose of this study was to compare a novel electrop...
Identification of novel biallelic LRRC6 variants in male Chinese patients with primary ciliary dyskinesia and infertility [0.03%]
具有原发性纤毛运动障碍和不育症的中国男性患者中新型双等位基因LRRC6变异的识别
Yunhao Li,Yong Li,Ying Wang et al.
Yunhao Li et al.
Purpose: The aim of this study is to identify the genetic cause of primary ciliary dyskinesia (PCD) and male infertility in two unrelated Han Chinese families. ...
LncRNA IGF2-AS promotes endometriosis progression through targeting miR-370-3p/IGF2 axis and activating PI3K/AKT/mTOR signaling pathway [0.03%]
长链非编码RNA IGF2-AS通过调控miR-370-3p/IGF2轴及激活PI3K/AKT/mTOR信号通路促进子宫内膜异位症进程
Xiaoyan Jin,Jingjing Feng,Xiao Cheng
Xiaoyan Jin
Purpose: Endometriosis, a gynecological disease, is difficult to be cured. Currently, to identify more potential biomarkers for the early diagnosis of endometriosis is urgently needed. Insulin like growth factor 2 (IGF2) ...
Modeling methods for busulfan-induced oligospermia and asthenozoospermia in mice: a systematic review and meta-analysis [0.03%]
用于研究小鼠马利兰所致的少精子症和弱精子症的模型方法:系统评价及荟萃分析
Ruiyang Pu,Jing Liu,Aiping Zhang et al.
Ruiyang Pu et al.
Objective: Modeling methods for busulfan-induced oligoasthenozoospermia are controversial. We aimed to systematically review the modeling method of busulfan-induced oligospermia and asthenozoospermia, and analyze changes ...
MicroRNAs: key regulators of the trophoblast function in pregnancy disorders [0.03%]
微RNA:妊娠疾病中滋养层功能的关键调节者
Lingli Liang,Yanjun Chen,Chunyan Wu et al.
Lingli Liang et al.
The placenta is essential for a successful pregnancy and healthy intrauterine development in mammals. During human pregnancy, the growth and development of the placenta are inseparable from the rapid proliferation, invasion, and migration o...
Preimplantation genetic testing for aneuploidy: helpful but not a first choice [0.03%]
胚胎植入前遗传学检测非整倍体:有用但不是首选方法
Sachiko Ohishi,Tetsuo Otani
Sachiko Ohishi
Purpose: This retrospective cohort study aimed to assess and compare the outcomes between cumulative live birth of patients with and without PGT-A and also between prior unsuccessful IVF cycles and PGT-A cycles among pati...
A novel homozygous C-terminal deletion in BTG4 causes zygotic cleavage failure and female infertility [0.03%]
BTG4基因新型纯合C末端缺失导致受精卵分裂失败和女性不育症
Yufeng Wang,Qingtao Qin,Yang Yang et al.
Yufeng Wang et al.
Purpose: We aimed to identify pathogenic variants in a female patient with primary infertility and recurrent failure of in vitro fertilization with zygotic cleavage failure. ...
Influence of climatic conditions in the mesothermal climate area on pregnancies following elective fresh single blastocyst transfer [0.03%]
中温带气候条件下选择性新鲜单囊胚移植后妊娠的影响
Hiroshi Matsumoto,Shu Hashimoto,Satoshi Mizuno et al.
Hiroshi Matsumoto et al.
Purpose: To investigate the effect of climatic parameters in the mesothermal climate area on clinical pregnancy and live birth following fresh single blastocyst transfer. ...
CircSTAM inhibits migration and invasion of trophoblast cells by regulating miR-148a-5p/PTEN axis [0.03%]
通过调节miR-148a-5p/PTEN轴 CircSTAM抑制滋养层细胞的迁移和侵袭
Lingfeng Chen,Jinyu Yan,Haiyan Zhang et al.
Lingfeng Chen et al.
Background: The mechanisms underlying the pathogenesis of preeclampsia (PE) remains unclear. Exploring the molecular players in PE progression can provide insights into targeted therapy. ...
A comprehensive investigation of human endogenous retroviral syncytin proteins and their receptors in men with normozoospermia and impaired semen quality [0.03%]
综合研究人类内源性逆转录病毒融膜蛋白和其在精子正常和精液质量异常的男性中的受体
Gizem Gamze Tas,Bikem Soygur,Omer Kutlu et al.
Gizem Gamze Tas et al.
Purpose: The study aims to investigate first the presence of Syncytin 2 and its receptor, MFSD2, in human sperm, and second whether the expressions of Syncytin 1, Syncytin 2, and their receptors, SLC1A5 and MFSD2, differ ...