Effect of peroxiredoxin 1 on the regulation of trophoblast function by affecting autophagy and oxidative stress in preeclampsia [0.03%]
过氧化氢酶1通过影响滋养细胞自噬和氧化应激在子痫前期滋养细胞功能调控中的作用研究
Meijuan Zhou,Junjun Guo,Shuxian Li et al.
Meijuan Zhou et al.
Purpose: PE is a pregnancy-specific syndrome and one of the main causes of maternal, fetal, and neonatal mortality. PRDX1 is an antioxidant that regulates cell proliferation, differentiation, and apoptosis. The aim of thi...
ART outcomes in lean compared to obese phenotypes of polycystic ovarian syndrome [0.03%]
苗条型和肥胖型多囊卵巢综合征患者的辅助生育结局比较研究
Yuval Fouks,Werner Neuhausser,David Ryley et al.
Yuval Fouks et al.
Research question: To investigate differences in reproductive outcomes among IVF patients with lean compared to obese polycystic ovarian syndrome (PCOS) phenotypes. ...
Oocyte secreted factors control genes regulating FSH signaling and the maturation cascade in cumulus cells: the oocyte is not in a hurry [0.03%]
卵子分泌因子控制累加细胞中调节FSH信号和成熟的基因：卵子不着急
Jose Buratini,Thaisy Tino Dellaqua,Paula Fernanda de Lima et al.
Jose Buratini et al.
Purpose: To assess the effects of the oocyte on mRNA abundance of FSHR, AMH and major genes of the maturation cascade (AREG, EREG, ADAM17, EGFR, PTGS2, TNFAIP6, PTX3, and HAS2) in bovine cumulus cells. ...
miR-4433a-3p promotes granulosa cell apoptosis by targeting peroxisome proliferator-activated receptor alpha and inducing immune cell infiltration in polycystic ovarian syndrome [0.03%]
miR-4433a-3p通过靶向过氧化物酶体增殖激活受体α并诱导免疫细胞浸润促进多囊卵巢综合征颗粒细胞凋亡
Lin Zhu,Xi Yao,Ying Mo et al.
Lin Zhu et al.
Background: Granulosa cell (GC) proliferation and apoptosis are critical events of the ovum energy supply, which lead to follicular growth retardation or atresia, and various ovulatory obstacles, eventually resulting in t...
Continuing the search for sperm-based determinants of early mammalian development [0.03%]
继续寻找基于精子决定哺乳动物早期发育的因素
David F Albertini
David F Albertini
Chunlei Guo,Xuejing Yin,Shuiping Yao
Chunlei Guo
Background: Although the importance of miRNA variants in female reproductive disorders has been frequently reported, the association between miRNA polymorphisms and recurrent pregnancy loss (RPL) has been poorly studied. ...
Surrogates' experience during the COVID-19 pandemic: mental health, social support, and relationship with intended parents [0.03%]
代孕者在COVID-19大流行期间的经历：心理健康、社会支持与与委托父母的关系
Samantha Yee,Jacob L Fine,Emma A Lindsay et al.
Samantha Yee et al.
Purpose: To examine surrogates' mental health, social support, and relationship with intended parents (IPs) during the COVID-19 pandemic from March 2020 to February 2022. ...
Endoplasmic reticulum in oocytes: spatiotemporal distribution and function [0.03%]
卵母细胞中的内质网：时空分布和功能
Xin Kang,Jing Wang,Liying Yan
Xin Kang
The storage and release of calcium ions (Ca2 +) in oocyte maturation and fertilization are particularly noteworthy features of the endoplasmic reticulum (ER). The ER is the largest organelle in the cell composed of rough ER, smooth ER, and ...
Kathryn J Go,Cynthia Hudson
Kathryn J Go
Cryopreservation, for many reasons, has assumed a central role in IVF treatment cycles, which has resulted in rapidly expanding cryopreserved oocyte and embryo inventory of IVF clinics. We aspire to consider how and with what resources and ...
Identification of novel candidate genes associated with meiotic aneuploidy in human embryos by whole-exome sequencing [0.03%]
通过全外显子组测序鉴定与人类胚胎减数分裂异常相关的新型候选基因
B Lledo,A Marco,R Morales et al.
B Lledo et al.
Purpose: To identify novel genetic variants responsible for meiotic embryonic aneuploidy. Methods: A prospective observational cohort s...