The dynamics of DNA methylation, histone methylation and acetylation during oocyte aging in mammalian species and possible interventions to regulate them [0.03%]
哺乳动物卵母细胞衰老过程中DNA甲基化、组蛋白甲基化和乙酰化的动态变化及可能的干预方式
Saffet Ozturk
Saffet Ozturk
Oocyt e development from non-growing to metaphase II (MII) stages is largely dependent on timely and correctly controlling gene expression. During the process of biological or postovulatory aging, the epigenetic mechanisms, particularly DNA...
Changes in sequencing technology used for preimplantation genetic testing for aneuploidy [0.03%]
胚胎植入前染色体异常遗传学检测中测序技术的应用进展
Vivianne Elizabeth Oltramare,Catherine McDermott,Paul Joseph Dunn
Vivianne Elizabeth Oltramare
The continued development of assisted reproductive technologies has aimed to improve pregnancy outcomes through screening methods for the identification of embryos with monogenic disorders, chromosomal aneuploidy or structural abnormalities...
Time-series clustering of the migration speed of nucleolus-precursor bodies in human zygotes and live birth following assisted reproductive technology [0.03%]
人囊胚前核体迁移速度的时间序列聚类及辅助生殖技术后的活产事件
Taketo Inoue,Sayumi Taguchi,Mikiko Uemura et al.
Taketo Inoue et al.
Purpose: Nucleolus-precursor body (NPB) migration speed in human zygotes predicts live birth after assisted reproduction. However, the impact of changes in NPB migration speed on live births was unclear. This study invest...
Live birth and other reproductive outcomes of mosaic and euploid embryos: a systematic review and meta-analysis [0.03%]
镶嵌型和正常嵌合胚胎的活产和其他生殖结果：系统回顾和荟萃分析
Eloiza Adriane Dal Molin,Gabriel Natan Pires,Virgínia Meneghini Lazzari
Eloiza Adriane Dal Molin
Advances in preimplantation genetic testing for aneuploidy (PGT-A) have improved embryo selection in assisted reproductive technologies (ART). However, the clinical significance of mosaic embryos remains uncertain. This systematic review an...
Virtual reality-based intervention to improve pre-operative anxiety in patients undergoing planned oocyte cryopreservation: a randomized clinical trial [0.03%]
基于虚拟现实的干预改善计划性卵泡冷冻保存患者术前焦虑的临床研究
Yael Suissa-Cohen,Rachelle Frenkel,Lea Nevo et al.
Yael Suissa-Cohen et al.
Purpose: To investigate the impact of virtual reality (VR) exposure on anxiety levels in patients undergoing planned oocyte cryopreservation. Methods: ...
Successful assisted reproduction treatment and its psychological outcomes for parents and children: a systematic review and meta-analysis [0.03%]
辅助生殖治疗的成功及其对父母和儿童的心理学影响：系统回顾及meta分析
Julia Jeannine Schmid,Ulrike Ehlert
Julia Jeannine Schmid
Purpose: Overcoming infertility through assisted reproductive technology (ART) is stressful and requires a high level of investment. Infertility, ART, and associated stress may continue to affect the family even after bir...
The obstetrical and infant outcomes of trophectoderm biopsy on preimplantation genetic testing embryos after frozen single embryo transfer cycles [0.03%]
胚胎植前遗传诊断囊胚期活检后冻融单囊胚移植的围产期结局分析
Rui Yang,Jiaxiang Wang,Chang Gao et al.
Rui Yang et al.
Purpose: To investigate if trophectoderm (TE) biopsy on preimplantation genetic testing (PGT) increases the risk of obstetrical and infant outcomes after frozen single blastocyst transfer cycles. ...
A novel targeted long-read sequencing-based preimplantation genetic testing method for α-thalassemia (tlrPGT-α-thal) [0.03%]
一种针对α-地中海贫血的新型靶向长读取测序基于植入前遗传学检测方法(tlrPGT-α-thal)
Qiuwen Shi,Tiantian Xie,Jianmin Li et al.
Qiuwen Shi et al.
Purpose: The purpose is to develop a preimplantation genetic testing (PGT) method for α-thalassemia in one reaction, without requiring a proband, using targeted long-range polymerase chain reaction (LR-PCR) followed by l...
Exposure to nanoscale graphene oxide deteriorates the quality of porcine oocytes via induction of oxidative stress and the apoptosis [0.03%]
纳米级石墨烯氧化物通过诱导氧化应激和凋亡恶化猪卵母细胞的质量
Yang Gao,Fuziaton Baharudin,Yunhai Zhang et al.
Yang Gao et al.
Purpose: Nano graphene oxide (nGO), as a type of engineered carbon nanomaterial, has witnessed significant growth in biomedical applications. Given the likelihood of accumulation of these materials in human tissues or org...
Successful pre-implantation genetic testing for autosomal recessive cutis laxa: clinical utility of a multidisciplinary team approach [0.03%]
植入前遗传学检测成功阻断常染色体隐性松弛皮肤综合征（cutis laxa）家系子代发病：多学科协作模式的临床意义
Qiuxiang Huang,Xiurong Yu,Lihua Mao et al.
Qiuxiang Huang et al.
Purpose: Pre-implantation genetic testing for monogenic disorders (PGT-M) enables couples at risk of transmitting serious genetic disorders to their offspring to give birth to healthy children. Here, we present an illustr...