Is a day 7 blastocyst predictive of the reproductive potential of sibling day 5 and day 6 blastocysts? [0.03%]
第7天囊胚能否预示其姐妹第5、6天囊胚的生殖潜能?
Jennia Michaeli,Natalie Ge,Ella Huszti et al.
Jennia Michaeli et al.
Purpose: To explore if a day 7 blastocyst is predictive of the reproductive potential of sibling day 5 or day 6 blastocysts? Methods: R...
Determinants of thermal homeostasis in the preimplantation embryo: a role for the embryo's central heating system? [0.03%]
前植入胚胎热稳态的决定因素:胚胎中央加热系统的角色?
Henry J Leese,Roger G Sturmey
Henry J Leese
A number of factors may impinge on thermal homeostasis in the early embryo. The most obvious is the ambient temperature in which development occurs. Physiologically, the temperature in the lumen of the female tract is typically lower than t...
LncRNA-NEAT1 blocks the Wnt/β-catenin signaling pathway by targeting miR-217 to inhibit trophoblast cell migration and invasion [0.03%]
长链非编码RNA-NEAT1通过靶向miR-217抑制Wnt/β-catenin信号通路从而抑制滋养细胞迁移侵袭性
Ling-Ling Jiang,Dan-Lin Yang,Qing Han et al.
Ling-Ling Jiang et al.
Objective: This study aimed to study the correlation between preeclampsia (PE) and lncRNA nuclear paraspeckle assembly transcript 1 (NEAT1), and to examine the molecular mechanisms behind the development of PE. ...
Obstetrical and neonatal outcomes after vitrified-warmed blastocyst transfer in day 1 rescue intracytoplasmic sperm injection cycles: a retrospective cohort study [0.03%]
单精子注射补救周期中解冻移植囊胚的围产期和新生儿结局:回顾性队列研究
Ming Li,Nan Zhang,Jin Huang et al.
Ming Li et al.
Background: Fertilization failure often occurs in conventional IVF cycles, and day 1 rescue ICSI is frequently recommended. In this study, the effect of rescue ICSI on obstetrical and neonatal outcomes after a single blas...
In cases with raised sperm DNA fragmentation, can sperm selection by magnetic-activated cell sorting or testicular sperm aspiration help improve reproductive outcomes? [0.03%]
磁激活细胞排序或睾丸精子抽吸挑选能否改善输精DNA片段升高病例的生育结局?
Krishna Chaitanya Mantravadi,Durga Rao
Krishna Chaitanya Mantravadi
Purpose: To evaluate the efficacy of magnetic-activated cell sorting (MACS) or testicular sperm aspiration (TESA) to improve reproductive outcomes in cases with elevated sperm DNA fragmentation undergoing assisted reprodu...
Randomized Controlled Trial
Journal of assisted reproduction and genetics. 2024 Jun;41(6):1507-1515. DOI:10.1007/s10815-024-03128-3 2024
Stringent criteria needed for germline genome editing of human IVF embryos [0.03%]
人类IVF胚胎的体细胞基因组编辑需要严格的标准
Alexis Heng Boon Chin,Jean-Didier Bosenge Nguma,Mohd Faizal Ahmad
Alexis Heng Boon Chin
Germline genome editing of IVF embryos is controversial because it is not directly health or lifesaving but is intended to prevent genetic diseases in yet-unborn future offspring. The following criteria are thus proposed for future clinical...
Evaluation of telomere length and telomerase activity on predicting in vitro fertilization treatment outcomes [0.03%]
端粒长度和端粒酶活性对体外受精治疗效果预测价值的评估
Persefoni Fragkiadaki,Elisavet Kouvidi,Anna Angelaki et al.
Persefoni Fragkiadaki et al.
The current article is a literature review aiming to provide an overview of the existing knowledge on the association between telomere length and telomerase activity and in vitro fertilization. Recently, telomeres have been used as an effec...
Bioinformatic analysis of the role of immune checkpoint genes and immune infiltration in the pathogenesis and development of premature ovarian insufficiency [0.03%]
免疫检查点基因及免疫浸润在卵巢早衰发病机制中的生物信息学分析
Xiyan Zhang,Ling Wang,Tongkun Yang et al.
Xiyan Zhang et al.
Purpose: With advances in immunology, increasing evidence suggests that immunity is involved in premature ovarian insufficiency (POI) pathogenesis. This study investigated the roles of immune checkpoint genes and immune c...
The effect of bariatric surgery on polycystic ovary syndrome patients' obstetric and neonatal outcomes: a population-based study [0.03%]
代谢手术对多囊卵巢综合征患者妊娠及新生儿结局的影响:基于人群的队列研究
Alyssa Hochberg,Mohammed S Bazarah,Haitham A Baghlaf et al.
Alyssa Hochberg et al.
Purpose: To examine the effect of bariatric surgery (BS) on obstetric and neonatal outcomes in patients with polycystic ovary syndrome (PCOS). Methods: ...
Fertility preservation in males with cancer of trends, region development, and efficacy in mainland China from 16 regions Chinese sperm banks [0.03%]
中国16个地区精子库的男性癌症生育力保存现状、地域发展及成效分析
Xiao Liu,Qiling Wang,Huiqiang Sheng et al.
Xiao Liu et al.
Purpose: Male cancer survivors experience confusion about fertility following cancer treatment. The aims of this study were to evaluate survivors' semen quality in different tumor type groups in China and to analyze the c...