Chemical reversion of age-related oocyte dysfunction fails to enhance embryo development in a bovine model of postovulatory aging [0.03%]
化学逆转年龄相关卵母细胞功能障碍无法提高牛排卵后衰老模型胚胎的发育能力
Ana Filipa Ferreira,Juliana Machado-Simões,Inês Moniz et al.
Ana Filipa Ferreira et al.
Purpose: There are no clinical treatments to prevent/revert age-related alterations associated with oocyte competence decline in the context of advanced maternal age. Those alterations have been attributed to oxidative st...
The relationship between Toll-like receptor-4 genes and preeclampsia outcomes [0.03%]
TLR4基因多态性与子痫前期妊娠结局的关系研究
Almagul Kurmanova,Gulfairuz Urazbayeva,Damilya Salimbayeva et al.
Almagul Kurmanova et al.
Purpose: The study aimed to analyse the relationship of the rs4986790 locus of the TLR4 gene with the overall risk of preeclampsia, including both its early and late forms. ...
Development of a machine learning-based prediction model for clinical pregnancy of intrauterine insemination in a large Chinese population [0.03%]
基于机器学习的预测模型在较大中国人群中宫腔内人工授精临床妊娠的预测研究
Jialin Wu,Tingting Li,Linan Xu et al.
Jialin Wu et al.
Purpose: This study aimed to evaluate the effectiveness of a random forest (RF) model in predicting clinical pregnancy outcomes from intrauterine insemination (IUI) and identifying significant factors affecting IUI pregna...
Rescue in vitro maturation using ovarian support cells of human oocytes from conventional stimulation cycles yields oocytes with improved nuclear maturation and transcriptomic resemblance to in vivo matured oocytes [0.03%]
使用体外常规刺激周期的卵巢支持细胞进行体外成熟救援可改善卵子核成熟并使其转录组更接近体内成熟的卵子
Bruna Paulsen,Sabrina Piechota,Ferran Barrachina et al.
Bruna Paulsen et al.
Purpose: Determine if the gene expression profiles of ovarian support cells (OSCs) and cumulus-free oocytes are bidirectionally influenced by co-culture during in vitro maturation (IVM). ...
The pregnancy outcomes among women receiving individualized algorithm dosing with follitropin delta: a systematic review of randomized controlled trials [0.03%]
Follicle 激素Delta个体化算法剂量对妊娠结局影响的系统评价及meta分析
Bogdan Doroftei,Ovidiu-Dumitru Ilie,Ana-Maria Dabuleanu et al.
Bogdan Doroftei et al.
Purpose: To investigate whether the ovarian stimulation with follitropin delta in an individualized algorithm-based manner is inferior to recombinant human-follicle stimulating's follitropin alfa or follitropin beta conve...
Kisspeptin expression during menstruation in PCOS patients undergoing ovulation induction and the correlation with early pregnancy [0.03%]
多囊卵巢综合征患者促排卵过程中经期 kisspeptin 表达及早孕期水平与妊娠的相关性研究
Qiao Peng,Siting Lv,Yidi Wen et al.
Qiao Peng et al.
Purpose: To examine the pattern of kisspeptin expression throughout the menstrual cycle in polycystic ovary syndrome (PCOS) patients under the ovulation induction and identify any possible associations with early pregnanc...
Supplementation with autologous adipose stem cell-derived mitochondria can be a safe and promising strategy for improving oocyte quality [0.03%]
自体脂肪干细胞来源的线粒体补充改善卵子质量的安全性和有效性研究
Sanath Udayanga Kankanam Gamage,Shu Hashimoto,Yuki Miyamoto et al.
Sanath Udayanga Kankanam Gamage et al.
Purpose: In our previous study, we confirmed that the supplementation of vitrified-warmed murine oocytes with autologous adipose stem cell (ASC)-derived mitochondria during intracytoplasmic sperm injection enhances post-f...
Identification of a novel CFAP61 homozygous splicing variant associated with multiple morphological abnormalities of the flagella [0.03%]
识别与多种鞭毛形态异常相关的新型CFAP61同种交配剪接变异体
Anne-Laure Barbotin,Angèle Boursier,Anne-Sophie Jourdain et al.
Anne-Laure Barbotin et al.
In this study, we investigated the role of a newly identified homozygous variant (c.1245 + 6T > C) in the CFAP61 gene in the development of multiple morphologically abnormal flagella (MMAF) in an infertile patient. Using exome sequencing, w...
Exposure to the reproductive endocrinology subspecialty among obstetrics and gynecology residency programs [0.03%]
妇产科住院医师项目中接触生殖内分泌学亚专业的情况
Rebecca Zeidman,Eve C Feinberg,MaryEllen Pavone
Rebecca Zeidman
Purpose: Prior studies found that Ob-gyn trainees believe they have inadequate experience in the REI subspecialty. We evaluated the amount of time devoted to REI within the 4-year rotation schedule of ACGME-accredited Ob-...
PDLIM3 knockdown promotes ferroptosis in endometriosis progression via inducing Gli1 degradation and blocking Hedgehog signaling pathway [0.03%]
PDLIM3敲低通过诱导Gli1降解和阻断Hedgehog信号通路促进子宫内膜异位症的铁死亡发展
Mingwei Liu,Xianxian Wang,Jiannan Zhu
Mingwei Liu
Aims: Current evidence suggests that there is no completely effective method for endometriosis (EMS) without trauma due to diverse adverse effects. Reliable evidence illustrates that inhibiting ferroptosis is a potential ...