A systematic review on the role of paternal factors in human placental development, function, and pregnancy-related disorders [0.03%]
关于父系因素在人类胎盘发育、功能及妊娠相关疾病中作用的系统评价
Jeslin Johnson,Sweta Nair,Dipty Singh et al.
Jeslin Johnson et al.
Background: The human placenta plays an important role in pregnancy and offspring health. The paternal genome contributes significantly to placental growth and development. While the maternal factors affecting gestational...
Embryo division timings and top-quality embryo rates in GnRH-Antagonist ICSI cycles: a comparison of hCG and dual trigger methods [0.03%]
黄体生成素释放激素拮抗剂ICSI周期中胚胎分割时间及优质胚胎率的比较:hCG扳机与双扳机方案
Nir Kugelman,Wisam Assaf,Idit Blais et al.
Nir Kugelman et al.
Purpose: To evaluate the impact of trigger types in Gonadotropin-releasing hormone (GnRH) antagonist IVF-ICSI cycles on embryo morphokinetics and top-quality embryo production. ...
Fertility treatments in transgender individuals: trends, clinical outcomes, and impact of testosterone on ovarian stimulation [0.03%]
性别重置者生育治疗的临床结局及睾丸激素对促排卵影响的研究趋势
Mireia Florensa,Mónica Galdú,Agustín Ballesteros et al.
Mireia Florensa et al.
Purpose: To describe the transgender population attending our clinics, the treatments of choice, and their clinical outcomes. To evaluate whether gender-affirming hormone therapy (GAHT) with testosterone in transmen affec...
Treatment with isotretinoin can improve de novo sperm production in nonobstructive azoospermia or cryptozoospermia [0.03%]
依西美坦治疗可改善非梗阻性无精子症或微量精子症的新生精子生成
Catherine Molly Jessup,John K Amory,Paul J Turek
Catherine Molly Jessup
Purpose: Retinoic acid (RA), a metabolite of vitamin A, is required for mammalian spermatogenesis. Clinically, intratesticular RA concentrations are lower in infertile men. In pilot studies, RA treatment is associated wit...
Expression of marker genes to assess the spermatogenic capacity in patients with idiopathic non-obstructive azoospermia [0.03%]
标记基因表达产物的检测在特发性非梗阻性无精子症患者中的应用价值分析
Shu Ding,Yangyi Fang,Li Zhang et al.
Shu Ding et al.
Purpose: To develop a robust quantitative method for assessing testicular spermatogenic capacity in patients with idiopathic non-obstructive azoospermia (iNOA), leveraging single-cell RNA sequencing to enhance diagnostic ...
Disparities in referrals to fertility preservation services for a pediatric and adolescent population [0.03%]
儿科和青少年群体中生育力保存服务转诊的差异性分析
Erin Isaacson,Susan J Woolford,Cheyney Dobson et al.
Erin Isaacson et al.
Purpose: This study aimed to determine if clinicians who provide potential gonadotoxic medications refer pediatric patients differently for a fertility preservation (FP) consultation based on race, ethnicity, socioeconomi...
Sperm and egg donors' views on identity release, donor offspring information and genetic testing [0.03%]
捐精者与捐卵者的观点:身份披露、后代信息及基因检测
Guido Pennings,Emilie Lassen,Josephine G Lemmen et al.
Guido Pennings et al.
Purpose: The study intended to find out whether sperm and egg donors hold different views on identifiability, information about donor offspring, genetic testing, and extended carrier screening. ...
Evaluating non-invasive Preimplantation Genetic Testing for Aneuploidy (niPGT-A) from spent culture medium: prolonged embryo culture to day 6 increases informativity without negatively impacting quality and live birth rates [0.03%]
无创囊胚培养液植入前非整倍体筛查:延长培养周期至第6天可提高检出率而不影响胚胎质量和活产率
Maria Banti,Mira Al Bishtawi,Estee Van Zyl et al.
Maria Banti et al.
Purpose: Embryos release cell-free DNA into spent culture medium (SCM), mostly from day 5 to day 6, making extended culture to day 6 (something done in IVF only for slow embryos) a preferred option in non-invasive preimpl...
Identification of Fowler syndrome (hydrocephaly-hydranencephaly proliferative vasculopathy) in a pregnancy following single euploid embryo transfer [0.03%]
单胚胎移植妊娠中福勒综合征(脑积水-无脑回症增生性血管病)的识别
Victoria Lazarov,Atoosa Ghofranian,Daniela Wilner et al.
Victoria Lazarov et al.
Background: Genetic carrier screening is a useful tool for couples looking to understand the genetic risk profile of their offspring. However, this method is limited in identifying rare genetic variants. ...
Placental miRNA profiling in assisted reproductive technology (ART) pregnancies [0.03%]
辅助生殖技术妊娠的胎盘miRNA谱分析
Deepali Sundrani,Sucheta Patil,Aishwarya Kapare et al.
Deepali Sundrani et al.
Purpose: Assisted reproductive technology (ART) procedures are associated with placental dysfunction involving dysregulation of several molecular factors and pathways. MicroRNAs (miRNAs) are crucial epigenetic regulators ...