Wen Chen,Li Dong,Chaofeng Wei et al.
Wen Chen et al.
Diminished ovarian reserve (DOR) is characterized by a decrease in the number and quality of oocytes, with its incidence increasing annually. Its pathogenesis remains unclear, making it one of the most challenging problems in the field of a...
Novel variants in PADI6 genes cause female infertility due to early embryo arrest [0.03%]
PADI6基因新变异导致早期胚胎停育型女性不孕症
Juepu Zhou,Ruolin Mao,Limin Gao et al.
Juepu Zhou et al.
Purpose: Early embryo arrest is characterized by premature termination of development in preimplantation embryos. Human subcortical maternal complex (SCMC) is a protein complex that is specifically expressed in mammalian ...
Greater PGT-A utilization in IVF clinics does not improve live birth rates but relates to IVF center ownership: a preliminary report [0.03%]
PGT-A在体外受精诊所中的使用增加并不能提高活产率但与IVF中心的所有权有关:初步报告
Pasquale Patrizio,Sarah Darmon,David H Barad et al.
Pasquale Patrizio et al.
This study aims to assess whether increased utilization for preimplantation genetic testing for aneuploidy (PGT-A) relates to improved live birth rates in IVF and whether IVF clinic ownership relates to PGT-A utilization. In a retrospective...
Women's healthcare providers' knowledge and practices surrounding fragile-X associated primary ovarian insufficiency (FXPOI) [0.03%]
脆性X染色体相关原发性卵巢功能不全(FXPOI)的女性医护提供者及其诊治知识和行为调查研究
Alexandra L Singleton,Heather S Hipp,Nadia Ali et al.
Alexandra L Singleton et al.
Purpose: This study investigates the knowledge gaps about fragile X-associated primary ovarian insufficiency (FXPOI) among women's healthcare providers. Previous research highlighted a lack of awareness regarding FXPOI as...
Clinical utilization and outcomes over eight consecutive years following oocyte cryopreservation [0.03%]
卵子冷冻八年临床应用及结局回顾性研究
Gayathree Murugappan,Mark Sikder,Sergio Vaccari et al.
Gayathree Murugappan et al.
Objective: To compare embryologic and clinical outcomes following oocyte cryopreservation (OC) and immediate fertilization for embryo cryopreservation (EC) in non-infertile patients. ...
Pathogenesis of testicular dysfunction in diabetes: exploring the mechanism and therapeutic interventions [0.03%]
糖尿病所致睾丸功能障碍的发病机制及干预措施研究进展
Olabimpe Caroline Badejogbin,Ojichukwuka Ebere Chijioke-Agu,Makinde Vincent Olubiyi et al.
Olabimpe Caroline Badejogbin et al.
Diabetes mellitus is a global epidemic contributing to the rising male infertility rates. Addressing testicular dysfunction in diabetic patients requires a multimodal strategy encompassing medication, lifestyle changes, early diagnosis, and...
Embryology outcomes of a device-based sperm separation technique compared to density gradient centrifugation using thawed spermatozoa-a sibling donor oocyte study [0.03%]
一种基于设备的精子分离技术与解冻精子密度梯度离心法的胚胎学结果比较——同捐卵供体研究
Eleftherios Gavriil,Anastasia Desli,Vasileios Geladaris et al.
Eleftherios Gavriil et al.
Objective: To evaluate whether the ZyMōt™ Multi 850 μl sperm separation device (SSD) effectively recovers motile spermatozoa from cryopreserved ejaculates and compare its effect on key embryology outcomes including fer...
Delays in the final stages of fertilization are strongly associated with trichotomous cytokinesis and cleavage arrest [0.03%]
晚期卵子受精障碍与三元细胞分裂和卵裂停滞密切相关
Giovanni Coticchio,Lorena Marchio,Alessandro Bartolacci et al.
Giovanni Coticchio et al.
Purpose: Recent evidence showed that the phase between pronuclear fading and the first cleavage is a perilous bridge connecting the zygote and the embryo. Indeed, delay in the short interval between pronuclear breakdown (...
The impact of Duostim protocol on pregnancy outcomes in infertile patients: A meta-analysis comparing single and double conventional stimulation cycles [0.03%]
双周期促排卵方案对不孕患者妊娠结局影响的系统评价和 Meta 分析
Youman Zeng,Weiwu Liu,Yudi Luo et al.
Youman Zeng et al.
Background: The DuoStim protocol has been proposed as an alternative to conventional single and double stimulation cycles in the treatment of infertility. However, its efficacy in improving pregnancy outcomes remains unce...