Novel STAG3 variant causes oligoasthenoteratozoospermia with high sperm aneuploidy rate [0.03%]
新型STAG3变异导致少弱畸精症伴高比例精子染色体非整倍体
Polina N Tsabai,Nadezhda S Pavlova,Taras V Shatylko et al.
Polina N Tsabai et al.
Purpose: Premature ovarian insufficiency (POI) and non-obstructive azoospermia (NOA) are the most severe forms of infertility. Pathogenic variants in a number of genes cause both disorders in siblings. One of them is STAG...
Genetic insights into non-obstructive azoospermia: Implications for diagnosis and TESE outcomes [0.03%]
非梗阻性无精子症的基因学见解：对诊断和睾丸精子抽取结果的意义
Shahrashoub Sharifi,Murat Dursun,Ayla Şahin et al.
Shahrashoub Sharifi et al.
Background: Non-obstructive azoospermia (NOA) is considered one of the most severe forms of male infertility. Despite the limited range of testicular phenotypes, NOA exhibits considerable genetic heterogeneity. The aim of...
Patient perspectives after receiving simulated preconception polygenic risk scores (PRS) for family planning [0.03%]
接受模拟孕前多基因风险评分(PRS)的患者的家庭规划视角
Maria Katz,Noor Siddiqui,Barry Behr et al.
Maria Katz et al.
Purpose: The study investigates patient perspectives on the use of Preimplantation Genetic Testing for Polygenic disease (PGT-P) to select embryos with lower risks for common polygenic diseases. Participant responses and ...
Spermatozoa centriole quality determined by FRAC may correlate with zygote nucleoli polarization-a pilot study [0.03%]
弗拉克法检测精子中心粒质量可能与受精卵核仁极性相关——一项初步研究
Derek F Kluczynski,Ankit Jaiswal,Min Xu et al.
Derek F Kluczynski et al.
Purpose: Spermatozoa centriolar defects can result in abnormal zygote functions. Recently, a method to quantify spermatozoa centriolar defects was developed named Fluorescence-Based Ratiometric Analysis of Sperm Centriole...
Analysis of Tanner stage in children conceived after the diagnosis of infertility: the DESCRT study [0.03%]
DESCRT研究中的儿童生殖能力分析
Jane Y Liu,Richard Hu,Robert H Lustig et al.
Jane Y Liu et al.
Purpose: Use of assisted reproductive technology (ART) could lead to abnormal pubertal development in children. We compared pubertal development in children conceived using ART to non-in vitro fertilization fertility trea...
Unveiling clinic variation in utilization of ICSI, PGT, and blastocyst transfer: a comprehensive study using the SART database (2014-2020) [0.03%]
基于SART数据库（2014-2020）的ICSI、PGT和囊胚移植使用情况的全面研究
Andrew Claffey,Anh Ngo,Donald McIntire et al.
Andrew Claffey et al.
Purpose: Many national recommendations have been made regarding practice patterns of assisted reproductive technology utilization (intracytoplasmic sperm injection (ICSI), preimplantation genetic testing (PGT), and blasto...
A rare viable delivery of a 45,X/46,XY mosaicism female with complete gonadal dysgenesis after receiving oocyte donation and overcoming multiple pregnancy complications [0.03%]
一位接受卵子捐赠并克服多次妊娠并发症后成功分娩的45,X/46,XY嵌合体完全gonadal发育不全女性的罕见存活案例
Yingliu Luo,Xi Liao,Juan Wen et al.
Yingliu Luo et al.
Purpose: Reporting a rare viable delivery of a 45,X/46,XY mosaicism female with complete gonadal dysgenesis (CGD) after receiving hormone replacement therapy (HRT), oocyte donation, and overcoming multiple pregnancy compl...
The relevance of female overweight in infertility treatment: a position statement of the Italian Society of Fertility and Sterility and Reproductive Medicine (SIFES-MR) [0.03%]
意大利生育与不育治疗学会(SIFES-MR)关于女性超重在不孕症治疗中的相关性的立场声明
Andrea Roberto Carosso,Alessandro Conforti,Danilo Cimadomo et al.
Andrea Roberto Carosso et al.
Purpose: Obesity is increasingly at the center of modern international healthcare systems. This is a position statement of the Italian Society of Fertility and Sterility and Reproductive Medicine (SIFES-MR) aimed at evalu...
Long-term outcomes and re-intervention rates in women undergoing mri-guided focused ultrasound (mrgfus) for uterine fibroids: a 7-year follow-up study [0.03%]
一项为期7年的随访研究：接受磁共振引导聚焦超声治疗子宫肌瘤女性患者的长期结局和再次干预率
Yael Inbar,Jaron Rabinovici,Rachael Sverdlove et al.
Yael Inbar et al.
Purpose: To assess the long-term outcomes of MR-guided focused ultrasound (MRgFUS) for treating uterine fibroids, focusing on re-intervention rates, pregnancy outcomes, and the onset of menopause over a 7-year follow-up p...
Clomiphene citrate throughout the duration of ovarian stimulation in patients with diminished ovarian reserve: an approach to decrease costs, reduce injection burden, and prevent premature ovulation [0.03%]
氯米芬柠檬酸在整个卵巢刺激期间用于卵巢功能减退患者的治疗：减少费用、降低注射负担和防止提前排卵的一种方法
Rachel S Mandelbaum,Samuel Melville,Aaron Masjedi et al.
Rachel S Mandelbaum et al.
Purpose: Clomiphene citrate (CC) is often utilized as an adjunct in in vitro fertilization (IVF) protocols during the first 5 days of stimulation for endogenous FSH release. However, due to its antiestrogenic mechanism of...