From within and without the gonadal niche: Capably capacitating a gamete's destiny [0.03%]
来自生殖器官微环境内外：有能力决定一个配子的最终命运
David F Albertini
David F Albertini
Laura Krygere,Ruta Bartasiene,Agne Kozlovskaja-Gumbriene et al.
Laura Krygere et al.
Purpose: To highlight the successful use of assisted reproductive technologies in achieving pregnancy and healthy childbirth in a woman with Swyer syndrome, a rare disorder of sex development characterized by gonadal dysg...
m6A RNA methylation dynamics during in vitro maturation of cumulus-oocyte complexes derived from adult or prepubertal sheep [0.03%]
成年和青春期前母羊卵丘-卵母细胞复合体体外成熟过程中的m6A RNA甲基化动态变化
Chiara Cosseddu,Sara Succu,Adele Frau et al.
Chiara Cosseddu et al.
Purpose: N6-methyladenosine (m6A) is the most prevalent base epigenetic modification within eukaryotic mRNAs. It participates in post-transcriptional regulation, including maternal RNA maintenance and decay in mouse oocyt...
Mitochondrial FIS1 level in cumulus cells correlates with morphological grades of human cleavage-stage embryos [0.03%]
人类裂殖期胚胎形态等级与卵丘细胞中线粒体FIS1水平相关联
Yizhen Sima,Sanbao Shi,Zhunyuan Min et al.
Yizhen Sima et al.
Purpose: Advanced-age women have a lower good-quality embryo rate (GQER) compared to young women. However, GQER varies widely within the same age group, suggesting that factors beyond age influence embryo quality. Mitocho...
Preimplantation genetic testing and disorders of placental implantation: a systematic review and meta-analysis [0.03%]
种植前遗传学检测和胎盘植入异常：系统评价和荟萃分析
Isaac J Chamani,Lauren L Taylor,Hailie Ciomperlik et al.
Isaac J Chamani et al.
Purpose: To evaluate whether embryo biopsy for preimplantation genetic testing (PGT) during in vitro fertilization (IVF) increases the risk of disorders related to abnormal placental implantation. ...
IVF success rates in individuals accessing preimplantation genetic testing for monogenic conditions (PGT-M): a single centre retrospective cohort study of 572 IVF cycles [0.03%]
对单基因疾病进行移植前遗传学检测的个体 vitro受精的成功率：一项关于572个 vitro受精周期的单一中心回顾性队列研究
Alice Poulton,Melody Menezes,Tristan Hardy et al.
Alice Poulton et al.
Purpose: To evaluate live birth rates per embryo transfer where the primary indication for assisted reproduction was preimplantation genetic testing for monogenic conditions. ...
A novel homozygous frameshift mutation in MCM8 causes primary gonadal dysgenesis in both genders [0.03%]
MCM8基因新的纯合移码突变导致两性原发性性腺发育不全
Jie Dong,Zhichuan Zou,Wenhua Wang et al.
Jie Dong et al.
Purpose: We aimed to demonstrate the genetic factors of primary gonadal dysgenesis in a consanguineous family characterized by underdeveloped testes and non-obstructive azoospermia (NOA) in a male and primary amenorrhoea ...
Analysis of pregnancy outcomes in patients with unexplained recurrent miscarriage assisted by IVF/ICSI with or without PGT-A [0.03%]
辅助IVF/ICSI并有或没有PGT-A的不明原因反复流产患者的妊娠结局分析
Ninghua Xu,Yulin Du,Zhuolun Su et al.
Ninghua Xu et al.
Purpose: The objective of this study was to evaluate the efficacy of preimplantation genetic testing for aneuploidy (PGT-A) in reducing the incidence of early miscarriage among patients diagnosed with unexplained recurren...
Perspectives and clinical practices on fertility preservation for young hematologic patients: a qualitative study of healthcare providers across multiple hospitals in China [0.03%]
中国多医院血液科医护人员对年轻患者生育力保存的看法和临床实践：一项定性研究
Li Wang,Jianfang Li,Tiexia Lu et al.
Li Wang et al.
Purpose: This study aims to understand healthcare providers' (HCPs) perspective and clinical practices regarding fertility preservation in young hematologic patients, particularly from hematology, reproductive medicine, a...
A diluted one-step warming protocol: survival of vitrified blastocyst [0.03%]
稀释一步升温方案对玻璃化冷冻囊胚存活率的影响
Emanuele Licata,Matthew VerMilyea,Brooke Ducote et al.
Emanuele Licata et al.
Purpose: The objective of this study was to compare the effects of two warming protocols (three step vs. one-step) on re-expansion and post-warming survival of human blastocysts previously vitrified using the standard vit...