Identification of candidate genes associated with mitotic-origin aneuploidy: a genome-wide association study [0.03%]
全基因组关联研究鉴定出与有丝分裂来源的非整倍体相关的候选基因
Zhengxin Lyu,Jianting An,Shi Song et al.
Zhengxin Lyu et al.
Purpose: Aneuploidy is the most common genetic abnormality in human embryos and is one of the leading causes of embryo transfer failure. We aimed to identify candidate genes linked to mitotic-origin aneuploidy. ...
Follicular fluid SCUBE1 as a novel angiogenesis-associated biomarker in women undergoing ART: a pilot study reflecting the follicular vascular microenvironment [0.03%]
一项关于卵泡血管微环境的初步研究：作为辅助生殖技术中与新生血管生成相关生物标志物的卵泡液SCUBE1
Yusuf Ziya Kizildemir,Hacer Uyanikoglu,Mehmet Incebiyik et al.
Yusuf Ziya Kizildemir et al.
Objective: To evaluate follicular fluid (FF) SCUBE1 levels as a novel angiogenesis-associated biomarker and investigate its role in reflecting the follicular vascular microenvironment and predicting ovarian response in wo...
Epigenetic sperm quality testing for predicting fertility treatment success: a real-world and multi-site analysis [0.03%]
表观遗传精子质量检测预测辅助生育治疗成功：基于真实世界和多中心数据分析
Kristin Brogaard,Susan Hudson,Carrie Bedient et al.
Kristin Brogaard et al.
Purpose: Infertility affects 1 in 6 couples, yet male fertility assessments often rely on semen analysis alone, which has limited predictive value for treatment success. This study evaluates an epigenetic tool for assessi...
Zeev Shoham,Yuval Or
Zeev Shoham
Homozygous C12orf40 variant contributes to severe oligoasthenoteratozoospermia and sperm sex chromosome aneuploidy [0.03%]
C12orf40同合子变异可导致严重的少弱畸形精子症及精子性染色体非整倍体变异
Yixin Chen,Jing Guo,Jing Wang et al.
Yixin Chen et al.
Purpose: Recurrent pregnancy loss (RPL) is frequently associated with embryonic aneuploidy, yet paternal genetic contributors remain poorly understood. In this study, we investigated the genetic cause of a couple with oli...
Heterogeneous offspring growth in spontaneous versus in vitro fertilization pregnancies: a retrospective cohort study [0.03%]
一项回顾性队列研究：自然受孕与体外受精受孕的后代生长存在异质性
Xiaoxi Li,Yang Ye,Na Li et al.
Xiaoxi Li et al.
Purpose: Observational studies suggest that children conceived via in vitro fertilization and embryo transfer (IVF-ET) may exhibit altered growth patterns compared to spontaneously conceived children. This study aimed to ...
Preimplantation genetic testing-M for pathogenic variant in CTC1 gene causing cerebroretinal microangiopathy [0.03%]
胚胎植入前遗传学检测-M即针对CTC1致病突变导致脑视网膜微血管病变的检测
Hongbin Zhou,Han Zhang,Huakun Zhang et al.
Hongbin Zhou et al.
Purpose: Cerebroretinal microangiopathy with calcifications and cysts (CRMCC) is an autosomal recessive genetic and multisystem disorder characterized by extensive intracranial calcifications, leukoencephalopathy, and ret...
What are the indirect costs of pursuing fertility care? A pilot survey study [0.03%]
辅助生育的间接成本有哪些？一项调查研究
Christopher Arkfeld,Stylianos Vagios,Victoria Fitz
Christopher Arkfeld
Purpose: It is widely accepted that pursuing fertility treatment is a costly endeavor, however, there are limited reports on the indirect costs of pursuing treatment-including the impact on professional careers, and costs...
Fertility preservation in turner syndrome: a case report integrating clinical presentation with genomic and molecular mechanistic analyses [0.03%]
特纳综合征的生育力保存：结合临床表现与基因组和分子机制分析的病例报告
Guosheng Deng,Donghua Zhang,Yuqing Lai et al.
Guosheng Deng et al.
Objective: This study aimed to explore the fertility potential in Turner syndrome through a detailed multidisciplinary analysis of a 45,X patient who achieved a successful live birth via IVF, integrating clinical, genetic...