Cohort profile: Copenhagen Hospital Biobank-chronic inflammatory disease-inflammatory bowel disease (CHB-CID:IBD) genetic cohort [0.03%]
哥本哈根医院生物样本库-慢性炎症性疾病：炎症性肠病（CHB-CID：IBD）遗传队列
Behrooz Darbani,Thorsten Brodersen,Anette Liljensøe et al.
Behrooz Darbani et al.
The Copenhagen Hospital Biobank-chronic inflammatory disease-inflammatory bowel disease (CHB-CID: IBD) cohort contributes to genetic research in inflammatory bowel disease, including Crohn's disease and ulcerative colitis. Of the 327,084 en...
Search for common genetic variants to allow reliable Mendelian randomization investigations into ketone metabolism [0.03%]
寻找酮体代谢的共同遗传变异以允许可靠的孟德尔随机化研究
Zhu Liduzi Jiesisibieke,Héléne Toinét Cronjé,C Mary Schooling et al.
Zhu Liduzi Jiesisibieke et al.
Ketogenic diets are popular among people aiming for weight management. Ketone supplementation has been linked to improved cognitive performance and increased risk of insulin resistance. We aim to identify common genetic variants that allow ...
Yi-Jiun Pan,Mei-Chen Lin,Chi-Fung Cheng et al.
Yi-Jiun Pan et al.
Infections in utero and early childhood are associated with an increased epilepsy risk; however, confounding by familial predisposition has not been adequately accounted for in previous studies. We aimed to assess the epilepsy risk attribut...
All-cause and cause-specific mortality in individuals with COPD in China: a 16-year follow-up cohort study [0.03%]
中国慢阻肺患者全因及各类死亡率的队列研究（16年随访）
Yalei Ke,Yuxuan Zhao,Dianjianyi Sun et al.
Yalei Ke et al.
The prevalence of chronic obstructive pulmonary disease (COPD) is rising in China, yet population-based evidence on COPD-related mortality risk remains limited. This study examined the association between prevalent COPD and all-cause and ca...
Non-linear Mendelian randomization: evaluation of effect modification in the residual and doubly-ranked methods with simulated and empirical examples [0.03%]
非线性孟德尔随机化：剩余法和双排序法效应修饰作用的评估——基于模拟数据集和实证数据集的研究
Fergus W Hamilton,David A Hughes,Tianyuan Lu et al.
Fergus W Hamilton et al.
Non-linear Mendelian randomisation (NLMR) is a relatively recently developed approach to estimate the causal effect of an exposure on an outcome where this is expected to be non-linear. Two commonly used techniques-based on stratifying the ...
The contribution of education-specific mortality trends to the life expectancy stagnation in England & Wales [0.03%]
英国和威尔士教育专属性死亡率趋势对预期寿命停滞不前的贡献
Jesús-Daniel Zazueta-Borboa,Leo van Wissen,Alison Sizer et al.
Jesús-Daniel Zazueta-Borboa et al.
The increase in life expectancy at birth (e0) has stagnated since 2011 in England & Wales (E&W). Prior research hypothesized that the stagnation is related to increasing austerity measures and widening socio-economic inequalities. We formal...
Re: The associations of long-term physical activity in adulthood with later biological aging and all-cause mortality- a prospective twin study [0.03%]
长期的体育锻炼与以后的生物衰老和全因死亡率的关系——一项前瞻性双胞胎研究
Yiwen Zhang,Edward L Giovannucci
Yiwen Zhang
What can be learned when multiple analysts arrive at different estimates [0.03%]
多个分析师得出不同估计时可以得到什么教训
Julia M Rohrer,George Davey Smith,Marcus Munafò
Julia M Rohrer
Dietary polyunsaturated fatty acid and risk of gout: a cohort study integrating genetic predisposition and metabolomics [0.03%]
饮食中的多不饱和脂肪酸与痛风风险的关系：一项整合遗传易感性和代谢组学的队列研究
Li Chen,Tianqi Tan,Qi Wu et al.
Li Chen et al.
Objectives: Gout is the most common inflammatory arthritis and affects quality of life. Dietary polyunsaturated fatty acids (PUFAs) have protective effects against various diseases, but its role in gout remains uncertain....
Postdiagnosis physical activity and dietary inflammatory and insulinemic potential with overall survival in men with nonmetastatic prostate cancer [0.03%]
前列腺癌诊断后的身体活动与饮食炎症和胰岛素潜能对无转移性前列腺癌男性患者总体生存率的影响
Dong Hoon Lee,Leandro F M Rezende,Gerson Ferrari et al.
Dong Hoon Lee et al.
Inflammation and insulin resistance are associated with increased mortality in the general population. However, it remains unclear how physical activity and proinflammatory/hyperinsulinemic diets influence overall survival in prostate cance...