Low-level exposure to arsenic in drinking water and risk of type 2 diabetes: a systematic review and meta-analysis [0.03%]
饮用水中低水平砷暴露与2型糖尿病发病风险的关联：系统评价和meta分析
Paolo Boffetta,Giulia Collatuzzo,K M Venkat Narayan
Paolo Boffetta
The association between diabetes and low-level arsenic exposure in drinking water has not been adequately investigated. We conducted a two-stage meta-analysis of dose-response relationships from studies reporting incidence or prevalence of ...
Counting sheep: Louis Pasteur and the first registered public vaccine trial [0.03%]
数羊去吧：路易·巴斯德与第一例注册公开疫苗试验
Cassandra Freitas,James A Hanley
Cassandra Freitas
During the COVID-19 pandemic, vaccine development took center stage in the media and minds of the global community. This same daily scrutiny was also applied to the first public registered vaccine trial of anthrax prevention among livestock...
Moving beyond risk ratios in sibling analysis: estimating clinically useful measures from family-based analysis [0.03%]
超越风险比的亲缘关系分析：基于家庭的分析中如何估计具有临床实用价值的指标
Viktor H Ahlqvist,Hugo Sjöqvist,Arvid Sjölander et al.
Viktor H Ahlqvist et al.
Findings from family-based analyses, such as sibling comparisons, are often reported using only odds ratios or hazard ratios. We demonstrate how this can be improved upon by applying the marginalized between-within framework. We provide an ...
Blood lipids and the risk of aortic aneurysm: results from the UK Biobank study and a systematic review and meta-analysis of cohort studies [0.03%]
英国生物银行研究和队列研究系统性回顾及合并分析结果：血脂与主动脉瘤风险的关系
Estelle Ioannidou,Dagfinn Aune,Ioannis Theodosopoulos et al.
Estelle Ioannidou et al.
Circulating lipids are potentially modifiable risk factors for aortic aneurysm, however, associations between levels of specific lipids and aortic aneurysm are unclear. We analysed associations between blood lipids and aortic aneurysm in th...
The multistep pathogenic hypothesis of amyotrophic lateral sclerosis is incompatible with the epidemiological data [0.03%]
多步骤致病假说与肌萎缩侧索硬化流行病学数据不符
Guglielmo Foffani,Daniele Urso,Josh Hiller et al.
Guglielmo Foffani et al.
Amyotrophic lateral sclerosis (ALS) is a multifactorial neurodegenerative disease whose incidence increases with age. According to the gene-time-environment hypothesis, ALS onset occurs through the interaction between genes and environmenta...
Emilio A L Gianicolo,Maria Blettner,Andreas Stang
Emilio A L Gianicolo
Social determinants disadvantage score and liver health in the All of Us Research Program [0.03%]
社会决定因素不利得分与“全民参与研究计划”的肝健康之间的关系
Xinyuan Zhang,Longgang Zhao,Kai Zhang et al.
Xinyuan Zhang et al.
Social determinants of health (SDOH) are crucial in shaping liver health outcomes, yet comprehensive assessments that span key SDOH domains are lacking. To address this knowledge gap, we developed a Social Determinants Disadvantage Score (S...
DiNetxify-a python package for three‑dimensional disease network analysis based on electronic health record data [0.03%]
基于电子健康记录数据的三维疾病网络分析的Python包DiNetxify
Can Hou,Haowen Liu,Viktor H Ahlqvist et al.
Can Hou et al.
The rapid expansion of large-scale electronic health record (EHR) data has underscored the necessity for advanced analytical methods, such as disease network analyses, to comprehensively identify and interpret multimorbidity patterns and di...
Can too much exercise kill you? A systematic review of the risk of a cardiovascular event or death from long term strenuous exercise [0.03%]
长期过度锻炼会致命吗？一项关于终身高强度锻炼引发心血管事件或死亡风险的系统性综述
Aleksandra Saulicz,David Abernethy,Darren Wraith
Aleksandra Saulicz
A considerable number of studies have highlighted that engaging in physical activity (PA) improves health and reduces risk of mortality. But is there a limit? Some evidence suggests a U-shaped exposure-response in which the protective benef...
Lifestyle factors and all-cause mortality in long-term cancer survivors: a population-based prospective cohort study [0.03%]
生活方式因素与长期癌症生存者的全因死亡率：一项基于人群的前瞻性队列研究
Chunsu Zhu,Melissa S Y Thong,Daniela Doege et al.
Chunsu Zhu et al.
The association between healthy lifestyles and mortality in cancer survivors remains inconclusive with few evidence among long-term cancer survivors (LTCS, survived ≥ 5 years post-diagnosis). Our study aims to investigate the association b...