Genetic risk score to enhance glaucoma case detection: a prospective double-blind screening study (EyeLife) in the population-based Lifelines cohort [0.03%]
增强青光眼病例检出的基因风险评分：一项在基于人群的Lifelines队列中开展的前瞻性双盲筛查研究（EyeLife）
Anna Neustaeter,Ilja M Nolte,Harold Snieder et al.
Anna Neustaeter et al.
Early detection of glaucoma prevents blindness but its low population-based prevalence impedes cost-effective screening. We investigated whether genetic pre-screening could increase the prior probability. Design, methods, and primary analys...
Different risks, same causes: educational attainment influences when, not from what, we die [0.03%]
同样的原因导致不同的风险：教育水平影响的是生命的何时而非如何落幕
Marie-Pier Bergeron-Boucher,Cosmo Strozza
Marie-Pier Bergeron-Boucher
Education is a well-established determinant of lifespan and mortality risk. Individuals with lower education levels experience higher mortality from nearly all causes. Yet since everyone ultimately dies from some condition, how does educati...
Loneliness around the world: patterns, predictors, and well-being implications [0.03%]
全球孤独状况：模式、预测因素及其对幸福感的影响
David Leblang,Dennis Wesselbaum
David Leblang
Loneliness is increasingly recognized as a global public health concern, yet cross-national evidence remains limited. Using data from the 2023-2024 Gallup World Poll, this study provides a globally representative description of loneliness a...
Cohort profile: Swiss personalized health network cohort consortium [0.03%]
人群队列概况：瑞士个性化健康网络队列 Consortium
Murielle Bochud,Samuel El Bouzaïdi Tiali,Jan Armida et al.
Murielle Bochud et al.
Swiss cohort studies provide high-quality longitudinal data, but finding and comparing relevant studies across cohorts has historically been challenging. The Swiss Personalized Health Network Cohort Consortium (SPHN-CC) was established to a...
The SINTER study: a recall-by-genotype design with multidimensional musculoskeletal phenotyping across internal-medicine outpatient clinics [0.03%]
SINTER研究：一种基于基因型的回溯设计，在内科门诊中进行多维度肌肉骨骼表型研究
Kirsty Huininga,Fjorda Koromani,Siwen Li et al.
Kirsty Huininga et al.
Bone mineral density (BMD) measured by DXA remains the clinical standard for diagnosing osteoporosis, but fails to capture the heterogeneity of skeletal fragility, particularly in patients with chronic diseases. We hereby describe the desig...
SARS-CoV-2 infection as a trigger of type 2 diabetes in adults: a population-based cohort study in Sweden using a double negative control design [0.03%]
瑞典基于人群的队列研究：新冠肺炎感染与成人2型糖尿病发病之间的关联——采用双重阴性对照设计的研究
Josefine Andreasson,Louise Bennet,Jonas Björk et al.
Josefine Andreasson et al.
Previous studies suggest an increased risk of new-onset type 2 diabetes (T2D) following SARS-CoV-2 infection, which may be subject to detection bias from increased health care contacts among the infected. We aimed to assess the causal effec...
Cohort profile: transformative research on equity and social determinants to uplift resilience and empower LGBTQ+ health in China (TREASURE) [0.03%]
研究概要：旨在提升中国LGBTQ+人群韧性及健康权的变革性研究（珍宝计划）
Peipei Zhao,Jingli Yang,Jialing Mu et al.
Peipei Zhao et al.
The Transformative Research on Equity And Social determinants to Uplift Resilience and Empower LGBTQ+ Health in China (TREASURE) is the first large-scale cohort study designed to investigate health conditions and social determinants of heal...
Adherence to the Mediterranean diet and risk of pancreatic cancer: an analysis of 2.3 million participants in the Pooling Project of Prospective Studies of Diet and Cancer (DCPP) [0.03%]
地中海饮食依从性与胰腺癌风险的关系：来自膳食和癌症前瞻性研究合并项目（DCPP）的230万参与者的分析结果
Qinting Shen,Claire Mobley,Molin Wang et al.
Qinting Shen et al.
Pancreatic cancer incidence is rising, yet few modifiable risk factors have been identified. The Mediterranean diet, which lowers inflammation and improves healthy weight maintenance and insulin control, may lower pancreatic cancer risk, ye...
Marta Ponzano,Stefano Renzetti,Chris Gennings et al.
Marta Ponzano et al.
Weighted Quantile Sum (WQS) regression is a statistical method for quantifying the association between multiple possibly correlated predictors and a health outcome, estimating both the joint effect of the predictors as well as their individ...
Dynamics of infection, vaccination and excess mortality during the COVID-19 pandemic among older individuals-a nationwide analysis [0.03%]
新冠肺炎疫情下我国老年人感染、疫苗接种和超额死亡的流行病学特征分析
Eva A S Koster,Marije H Sluiskes,Hein Putter et al.
Eva A S Koster et al.
The Coronavirus Diseases (COVID-19) pandemic led to excess mortality in many countries, i.e., to more deaths than expected. Older individuals generally had higher absolute risks of excess death. The complex dynamics of infection, vaccinatio...