Sabine Naudin,Joshua N Sampson,Steven C Moore et al.
Sabine Naudin et al.
Pancreatic ductal carcinoma (PDAC) is highly fatal with limited understanding of mechanisms underlying its carcinogenesis. We comprehensively investigated whether lipidomic measures were associated with PDAC in two prospective studies. We m...
Maryam S Daneshpour,Mahdi Akbarzadeh,Hossein Lanjanian et al.
Maryam S Daneshpour et al.
The Tehran cardiometabolic genetic study (TCGS) is a large population-based cohort study that conducts periodic follow-ups. TCGS has created a comprehensive database comprising 20,367 participants born between 1911 and 2015 selected from fo...
The association of a combined healthy lifestyle with the risk of postmenopausal breast cancer subtypes in the Netherlands Cohort Study [0.03%]
荷兰协作队列研究中健康生活方式与绝经后乳腺癌亚型风险之间的关联性分析
Piet A van den Brandt
Piet A van den Brandt
The association between combined healthy lifestyle and postmenopausal breast cancer risk has been studied in various cohort studies, but only few evaluated the association with estrogen/progesterone (ER/PR) receptor subtypes of breast cance...
Leveraging family history data to disentangle time-varying effects on disease risk using lifecourse mendelian randomization [0.03%]
利用家族历史数据解开生命历程梅涅尔随机化对疾病风险的时变效应
Tom G Richardson,Helena Urquijo,Michael V Holmes et al.
Tom G Richardson et al.
Lifecourse Mendelian randomization is a causal inference technique which harnesses genetic variants with time-varying effects to develop insight into the influence of age-dependent lifestyle factors on disease risk. Here, we apply this appr...
Dietary patterns, brain morphology and cognitive performance in children: Results from a prospective population-based study [0.03%]
饮食模式、大脑形态和儿童认知表现：一项前瞻性人群研究的结果
Yuchan Mou,Elisabet Blok,Monica Barroso et al.
Yuchan Mou et al.
Dietary patterns in childhood have been associated with child neurodevelopment and cognitive performance, while the underlying neurobiological pathway is unclear. We aimed to examine associations of dietary patterns in infancy and mid-child...
Vitamin D status during pregnancy: a role in intergenerational reproductive health? [0.03%]
维生素D与母胎健康及跨世代生殖健康的关系探究
Alexandra C Purdue-Smithe,Christine R Langton,JoAnn E Manson
Alexandra C Purdue-Smithe
Kjetil Bjornevik,Alberto Ascherio
Kjetil Bjornevik
Age-specific effects of weight-based body size on fracture risk in later life: a lifecourse Mendelian randomisation study [0.03%]
基于体重的体型对晚年骨折风险的影响具有年龄特异性：一种生命周期孟德尔随机化研究
Grace Marion Power,Jonathan H Tobias,Timothy M Frayling et al.
Grace Marion Power et al.
Musculoskeletal conditions, including fractures, can have severe and long-lasting consequences. Higher body mass index in adulthood is widely acknowledged to be protective for most fracture sites. However, sources of bias induced by confoun...
Plant-based dietary patterns and the risk of digestive system cancers in 3 large prospective cohort studies [0.03%]
基于植物的膳食模式与三大前瞻性队列研究中消化系统癌症风险的关系
Jihye Kim,Jaewon Khil,Hanseul Kim et al.
Jihye Kim et al.
Little is known about the relation between plant-based dietary patterns and digestive system cancers. This study investigated the prospective association between 3 pre-defined indices of plant-based dietary pattern and risk of digestive sys...
Sarah Bauermeister,Mukta Phatak,Kelly Sparks et al.
Sarah Bauermeister et al.
Data discovery, the ability to find datasets relevant to an analysis, increases scientific opportunity, improves rigour and accelerates activity. Rapid growth in the depth, breadth, quantity and availability of data provides unprecedented o...