The influence of growth and sex hormones on risk of alzheimer's disease: a mendelian randomization study [0.03%]
生长和性激素与阿尔茨海默病发病风险的关联：孟德尔随机化研究
Chris Ho Ching Yeung,Shiu Lun Au Yeung,Man Ki Kwok et al.
Chris Ho Ching Yeung et al.
Alzheimer's disease is more prevalent in women, possibly due to sex or growth hormones but existing evidence is inconclusive. We investigated whether genetically predicted sex and growth hormones are associated with risk of Alzheimer's dise...
Synergistic effect of non-alcoholic fatty liver disease and history of gestational diabetes to increase risk of type 2 diabetes [0.03%]
非酒精性脂肪肝病与妊娠糖尿病史的协同作用增加2型糖尿病风险
Yoosun Cho,Yoosoo Chang,Seungho Ryu et al.
Yoosun Cho et al.
Whether non-alcoholic fatty liver disease (NAFLD) improves risk prediction for subsequent type 2 diabetes mellitus (T2DM) in women with prior gestational diabetes mellitus (pGDM) is uncertain. We examined the combined effects of NAFLD and p...
Falsification of the instrumental variable conditions in Mendelian randomization studies in the UK Biobank [0.03%]
英国生物样本库中孟德尔随机化研究中的工具变量条件伪造问题
Kelly Guo,Elizabeth W Diemer,Jeremy A Labrecque et al.
Kelly Guo et al.
Mendelian randomization (MR) is an increasingly popular approach to estimating causal effects. Although the assumptions underlying MR cannot be verified, they imply certain constraints, the instrumental inequalities, which can be used to fa...
Residential proximity to petrol stations and risk of childhood leukemia [0.03%]
居住环境靠近加油站与儿童期白血病的发病风险的关系研究
Marcella Malavolti,Carlotta Malagoli,Tommaso Filippini et al.
Marcella Malavolti et al.
Petrol stations emit benzene and other contaminants that have been associated with an increased risk of childhood leukemia. We carried out a population-based case-control study in two provinces in Northern Italy. We enrolled 182 cases of ch...
Lympho-hematopoietic malignancies risk after exposure to low dose ionizing radiation during cardiac catheterization in childhood [0.03%]
童年时期在接受心脏导管插管过程中接触微剂量电离辐射后患淋巴和血液系统恶性肿瘤的风险
Kossi D Abalo,Sophie Malekzadeh-Milani,Sébastien Hascoët et al.
Kossi D Abalo et al.
Pediatric patients with congenital heart disease (CHD) often undergo low dose ionizing radiation (LDIR) from cardiac catheterization (CC) for the diagnosis and/or treatment of their disease. Although radiation doses from a single CC are usu...
COVID-19 mortality and use of intensive care among ethnic minorities - a national register-based Danish population study [0.03%]
新冠肺炎死亡率和重症监护使用情况的族裔差异——一项基于全国登记册的丹麦人口研究
Marie Norredam,Sabrina Islamoska,Jørgen Holm Petersen et al.
Marie Norredam et al.
Migrants and ethnic minorities are disproportionately affected by the Coronavirus Disease 2019 (COVID-19) pandemic compared to the majority population. Therefore, we studied mortality and use of mechanical ventilation (MV) by country of bir...
The role of environmental factors on sporadic Creutzfeldt-Jakob disease mortality: evidence from an age-period-cohort analysis [0.03%]
环境因素在散发性克雅氏病死亡率中的作用：来自年龄-时期-队列分析的证据
Angéline Denouel,Jean-Philippe Brandel,Danielle Seilhean et al.
Angéline Denouel et al.
Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common form of prion diseases. The causes of sCJD are still unknown and exogenous factors may play a role. Worldwide, the number of patients with sCJD has progressively increased over ti...
Diabetes mellitus, prediabetes and the risk of Parkinson's disease: a systematic review and meta-analysis of 15 cohort studies with 29.9 million participants and 86,345 cases [0.03%]
糖尿病、前期糖尿病与帕金森病风险：一项包含2990万参与人群和86345例患者的15项队列研究的系统综述及荟萃分析
Dagfinn Aune,Sabrina Schlesinger,Yahya Mahamat-Saleh et al.
Dagfinn Aune et al.
A diagnosis of diabetes mellitus and prediabetes has been associated with increased risk of Parkinson's disease (PD) in several studies, but results have not been entirely consistent. We conducted a systematic review and meta-analysis of co...
Domantas Jasilionis,Alyson A van Raalte,Sebastian Klüsener et al.
Domantas Jasilionis et al.
This article contributes to the discussion on the determinants of diverging life expectancy in high-income countries, with a focus on Germany. To date, much of this discourse has centered around the social determinants of health, issues of ...