Incidence, prevalence and mortality of chronic liver diseases in Sweden between 2005 and 2019 [0.03%]
2005年至2019年瑞典慢性肝病的发病率、患病率和死亡率
Patrik Nasr,Erik von Seth,Raphaela Mayerhofer et al.
Patrik Nasr et al.
Background: Updated data on the incidence, prevalence, and regional differences of chronic liver disease are missing from many countries. In this study, we aimed to describe time trends, incidence, prevalence, and mortali...
Observational Study
European journal of epidemiology. 2023 Sep;38(9):973-984. DOI:10.1007/s10654-023-01028-x 2023
How hazardous are hazard ratios? An empirical investigation of individual patient data from 27 large randomized clinical trials [0.03%]
风险比有多大的危害？对来自27项大型随机临床试验的个体患者数据的经验研究
Alexandra Strobel,Andreas Wienke,Oliver Kuss
Alexandra Strobel
The use of hazard ratios as the standard treatment effect estimators for randomized trials with time-to-event outcomes has been the subject of repeated criticisms in recent years, e.g., for its non-collapsibility or with respect to (causal)...
Drinking alcohol in moderation is associated with lower rate of all-cause mortality in individuals with higher rather than lower educational level: findings from the MORGAM project [0.03%]
适度饮酒与较高的教育水平相关的全因死亡率较低：MORGAM项目的结果
Augusto Di Castelnuovo,Marialaura Bonaccio,Simona Costanzo et al.
Augusto Di Castelnuovo et al.
The association between socioeconomic status (SES) and alcohol-related diseases has been widely explored. Less is known, however, on whether the association of moderate drinking with all-cause mortality is modified by educational level (EL)...
Genome-wide epistasis study highlights genetic interactions influencing severity of COVID-19 [0.03%]
全基因组表型相关分析揭示影响COVID-19严重性遗传因素间的相互作用
Shiqi Lin,Xingjian Gao,Frauke Degenhardt et al.
Shiqi Lin et al.
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to life-threatening respiratory symptoms. Understanding the genetic basis of the prognosis of COVID-19 is important for ...
About the associations of vitamin D deficiency and biomarkers of systemic inflammatory response with all-cause and cause-specific mortality in a general population sample of almost 400,000 UK Biobank participants [0.03%]
关于维生素D缺乏与全身炎症反应生物标志物在近40万英国生物样本库受试者中的相关性及全因死亡率和病因而死的死亡率研究
Sha Sha,Tafirenyika Gwenzi,Li-Ju Chen et al.
Sha Sha et al.
It is unknown whether the well-known association between vitamin D deficiency and mortality could be explained by the immune system modulating effects of vitamin D, which may protect from a systemic inflammatory response (SIR) to adverse he...
Genetic variants in the adenosine triphosphate-binding cassette transporter A1 and risk of age-related macular degeneration [0.03%]
腺苷三磷酸结合盒转运蛋白A1基因变异与年龄相关性黄斑变性的发病风险关系研究
Liv Tybjærg Nordestgaard,Mette Christoffersen,Shoaib Afzal et al.
Liv Tybjærg Nordestgaard et al.
Genetic variants in ABCA1 are associated with higher concentrations of high-density lipoprotein (HDL) cholesterol. Higher HDL cholesterol concentrations are observationally and genetically associated with higher risk of age-related macular ...
Randomized controlled trials insufficiently focus on reducing medical overuse [0.03%]
随机对照试验不足以减少过度医疗现象
Jasper M Kampman,Oren Turgman,Ward H van der Ven et al.
Jasper M Kampman et al.
Target trial emulation of aspirin after diagnosis of colorectal polyps [0.03%]
确诊结肠直肠息肉后的阿司匹林靶标试验模拟研究
Louise Emilsson,Mingyang Song,Jonas F Ludvigsson
Louise Emilsson
Backgound and aims: Previous research on the potential chemoprotective effect of aspirin for colorectal cancer (CRC) shows conflicting results. We aimed to emulate a trial of aspirin intiation in individuals with incident...
Influence of analytic methods, data sources, and repeated measurements on the population attributable fraction of lifestyle risk factors [0.03%]
分析方法、数据来源和重复测量对生活方式危险因素人群归因分数的影响
You Wu,Hanseul Kim,Kai Wang et al.
You Wu et al.
Population attributable risk (PAR%) reflects the preventable fraction of disease. However, PAR% estimates of cancer have shown large variation across populations, methods, data sources, and timing of measurements. Three statistical methods ...
Bruce M Psaty,Ramachandran S Vasan
Bruce M Psaty
In this commentary, the authors discuss the potential mechanisms for the finding of an association between myocardial infarction and cancer incidence. ...