Can too much exercise kill you? A systematic review of the risk of a cardiovascular event or death from long term strenuous exercise [0.03%]
长期过度锻炼会致命吗？一项关于终身高强度锻炼引发心血管事件或死亡风险的系统性综述
Aleksandra Saulicz,David Abernethy,Darren Wraith
Aleksandra Saulicz
A considerable number of studies have highlighted that engaging in physical activity (PA) improves health and reduces risk of mortality. But is there a limit? Some evidence suggests a U-shaped exposure-response in which the protective benef...
Lifestyle factors and all-cause mortality in long-term cancer survivors: a population-based prospective cohort study [0.03%]
生活方式因素与长期癌症生存者的全因死亡率：一项基于人群的前瞻性队列研究
Chunsu Zhu,Melissa S Y Thong,Daniela Doege et al.
Chunsu Zhu et al.
The association between healthy lifestyles and mortality in cancer survivors remains inconclusive with few evidence among long-term cancer survivors (LTCS, survived ≥ 5 years post-diagnosis). Our study aims to investigate the association b...
Early-onset colorectal cancer is associated with metabolic disorders: a systematic review and meta-analysis [0.03%]
代谢性疾病与早期结直肠癌的关联：一项系统综述和荟萃分析
Jacques Hilbert,Fernando Topfstedt,Laura Matuschik et al.
Jacques Hilbert et al.
Early-onset colorectal cancer (eoCRC), defined by diagnosis before age 50, is increasing worldwide. Metabolic disorders are suspected contributors. We performed a systematic review and meta-analysis to quantify associations between eoCRC an...
COVID-19 vaccination and short-term mortality risk: a nationwide self-controlled case series study in The Netherlands [0.03%]
荷兰全国自我控制病例系列研究中的Covid-19疫苗接种与短期死亡风险的关系
Isabel A L Slurink,Annemarijn R de Boer,Marc J M Bonten et al.
Isabel A L Slurink et al.
Excess mortality during the COVID-19 pandemic partly exceeded COVID-19-related deaths, indicating that other causes may have contributed. We conducted a retrospective data-linkage study including all Dutch inhabitants to investigate the imp...
Academic impact and research data utilisation of the clinical practice research datalink: scientometric analyses [0.03%]
基于科学计量分析的临床实践研究数据链的学术影响力及科研数据利用状况调查研究
Marta Pineda-Moncusí,Maria Rahman,Eleanor L Axson et al.
Marta Pineda-Moncusí et al.
Since its establishment in the late 1980s, the UK Clinical Practice Research Datalink (CPRD) has become one of the most widely utilised data resources in both national and international research. Its value lies in the richness, scale and qu...
Quantifying the contribution of social disconnection to the mortality gap associated with mental disorders: a decomposition analysis [0.03%]
量化社会隔离在精神障碍相关死亡率差距中的作用：分解分析
Lisbeth Mølgaard Laustsen,Linda Ejlskov,Danni Chen et al.
Lisbeth Mølgaard Laustsen et al.
Individuals with mental disorders face a substantially higher risk of mortality and are more likely to be lonely, socially isolated, and with low social support compared to those without mental disorders. We aimed to quantify the extent to ...
Yong-Qiao He,Wen-Qiong Xue,Hua Diao et al.
Yong-Qiao He et al.
The global rise of non-communicable diseases (NCDs) presents an urgent public health challenge, particularly in regions undergoing rapid economic and demographic transitions. Guangdong Province, China's most populous and economically advanc...
Air pollutants, genetic susceptibility, and the risk of age-related macular degeneration: a large prospective cohort study [0.03%]
空气污染、遗传易感性和年龄相关性黄斑变性的风险：一项大型前瞻性队列研究
Shengli Chen,Gongyue Wang,Xin Guan et al.
Shengli Chen et al.
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss worldwide. However, evidence regarding the relationship between air pollution and AMD is limited, and the modifying effect of genetic susceptibility on th...
Why do women live longer than men, but spend more time in poor health? A decomposition analysis of the gender gap in unhealthy life years across Europe [0.03%]
为何女性寿命长于男性，但不健康的生命年份却更多？欧洲各国预期无健康生命年的性别差距分解分析
Magdalena Muszynska-Spielauer,Paola Di Giulio,Yuka Minagawa et al.
Magdalena Muszynska-Spielauer et al.
This study tests the "longevity hypothesis," which posits that women's greater number of years spent in poor health is primarily a direct consequence of their longer survival. We analyse gender differences in unhealthy life years (ULY) at a...
Maternal hormonal contraception use and childhood cancer risk: a systematic review and meta-analysis [0.03%]
母亲使用避孕药与儿童患癌症风险的关系：系统评价和meta分析
Sif E Carlsen,Emily Jarden,Caroline H Hemmingsen et al.
Sif E Carlsen et al.
Observational studies have linked maternal hormonal contraception use to childhood cancer risk, but findings are inconsistent. A systematic review was conducted of this potential relationship. A systematic search was performed in PubMed, Em...