TMEM205 promotes M2-like macrophage polarization and advances the progression of triple-negative breast cancer [0.03%]
TMEM205通过促进M2型巨噬细胞极化来推进三阴性乳腺癌进展
Yining Zhang,Jing Peng,Teng Ma et al.
Yining Zhang et al.
Introduction: Triple-negative breast cancer (TNBC) is a highly aggressive subtype and lacks effective targeted therapies. Transmembrane protein 205 (TMEM205) has been implicated in tumor progression and immune resistance,...
Prognostic and predictive performance of PREDICT 2.1, PREDICT v3, and RSClin in node-negative early breast cancer: a TEAM pathology substudy [0.03%]
PREDICT 2.1、PREDICT v3和RSClin在淋巴结阴性早期乳腺癌中的预后及预测性能：TEAM病理学亚组研究
Andréanne Leblanc,Ana-Alicia Beltran-Bless,Gregory R Pond et al.
Andréanne Leblanc et al.
Background: Despite widespread use of clinico-pathologic and genomic risk scores in early breast cancer (EBC), questions remain as to whether they are predictive, prognostic, or both. We evaluated risk score performance w...
Refined risk stratification in residual triple-negative breast cancer after neoadjuvant therapy using residual cancer burden class and lymphovascular invasion [0.03%]
新辅助治疗后三阴性乳腺癌残留病灶的精细化风险分层研究——残余肿瘤负荷分级与淋巴管血管浸润联合评估模型
Tae Hoon Lee,Hyunwoo Lee,Jeong Yun Jang et al.
Tae Hoon Lee et al.
Purpose: This study aimed to identify prognostic factors and to stratify recurrence risk using a prognostic model incorporating the identified factors in patients with residual triple-negative breast cancer (TNBC) followi...
Diagnostic accuracy of tumor bed biopsy for predicting pathological complete response in breast cancer patients achieving clinical complete response after neoadjuvant chemotherapy: a meta-analysis [0.03%]
新辅助化疗后临床完全缓解的乳腺癌患者中肿瘤床活检预测病理完全缓解的诊断准确性：一项系统综述和荟萃分析
Garvit Garg,S Bharath,Abhishek Krishna et al.
Garvit Garg et al.
Purpose: With growing interest in surgical de-escalation for breast cancer, tumor bed biopsy (TBB) after neoadjuvant chemotherapy (NACT) has been proposed as a tool to predict pathological complete response (pCR). This me...
Postoperative complications after salvage mastectomy and repeat breast-conserving surgery in patients with IBTR after previous breast-conserving surgery: a multicenter, retrospective cohort study [0.03%]
先前接受过保乳手术(IBTR)后行挽救性乳房切除术与重复保乳手术患者的术后并发症：一项多中心回顾性队列研究
Laura M Tiels,Coco J E F Walstra,Adri C Voogd et al.
Laura M Tiels et al.
Background: In patients with ipsilateral breast tumor recurrence (IBTR) previously treated with breast-conserving surgery (BCS) followed by radiotherapy, salvage mastectomy (SM) is still considered standard of care. Curre...
Multicenter Study
Breast cancer research and treatment. 2026 Feb 4;215(3):71. DOI:10.1007/s10549-026-07908-6 2026
The relationship between impaired upper-body function, quality of life and breast cancer-related lymphoedema: results from a prospective, population-based cohort study [0.03%]
关于上肢功能障碍、生活质量以及乳腺癌相关淋巴水肿关系的结果：一项前瞻性人群队列研究
Hildegard M Reul-Hirche,Matthew R Dunn,Melanie L Plinsinga et al.
Hildegard M Reul-Hirche et al.
Purpose: To describe upper-body function in women after breast cancer treatment; and to explore the relationship between upper-body function, quality of life and breast cancer- related lymphoedema up to 7-years post-diagn...
Exercise training decreases Neuregulin-1 concentrations in HER2-positive breast cancer patients undergoing adjuvant trastuzumab: the CARDAPAC study [0.03%]
运动训练可降低赫赛汀治疗阳性乳腺癌患者中神经调节蛋白-1的浓度：来自CARDAPAC研究的结果
Quentin Jacquinot,Gaël Ennequin,Antoine Falcoz et al.
Quentin Jacquinot et al.
Purpose: Trastuzumab used for the treatment of patients with HER2-positive breast cancer induces cardiotoxicity. The NRG1/HER pathway plays a central role in human cardiovascular physiology; however, the link between exer...
Randomized Controlled Trial
Breast cancer research and treatment. 2026 Feb 4;215(3):69. DOI:10.1007/s10549-026-07903-x 2026
Oncologic safety of prophylactic nipple-sparing mastectomy: Outcomes of 1,255 cases exceeding a 6-year median follow-up [0.03%]
预防性保留乳头乳腺切除术的肿瘤安全性：中位随访超过6年的1255例结果分析
Thomas Amburn,Fatemeh P Parvin-Nejad,Varadan Sevilimedu et al.
Thomas Amburn et al.
Background: Prophylactic nipple-sparing mastectomy (PNSM) is performed to prevent the development of breast cancer. Despite the increasing usage of PNSM, large-cohort, long-term follow-up data is lacking. We aim to review...
Association of low muscle mass and obesity with mortality and cardiovascular outcomes in breast cancer: a population-based study [0.03%]
肌少症和肥胖与乳腺癌患者死亡率及心血管结局的关系：基于人口的队列研究
Sohyun Chun,Han Rim Lee,Jin-Hyung Jung et al.
Sohyun Chun et al.
Purpose: Obesity and low muscle mass (LMM) have been associated with adverse outcomes in cancer population. However, their individual and combined effects on long-term mortality and cardiovascular disease (CVD) outcomes i...
Fertility preservation in breast cancer patients: a systematic review and summary of current evidence and recommendations [0.03%]
乳腺癌患者的生育力保存：当前证据和建议的系统性回顾总结
Yaxin Chen,Ruirui Wang,Lei Wu et al.
Yaxin Chen et al.
Background: With the rising survival rates of breast cancer, fertility preservation has become a paramount concern for young patients throughout their anticancer treatment. We conducted a systematic review to assess and s...