Inhibition of Angiopoietin-2 rescues sporadic brain arteriovenous malformations by reducing pericyte loss [0.03%]
血管生成素-2抑制通过减少周细胞丢失来拯救散发性脑动静脉畸形
Tianqi Tu,Shikun Zhang,Jingwei Li et al.
Tianqi Tu et al.
Brain arteriovenous malformations (bAVMs) are a major cause of hemorrhagic stroke in children and young adults. These lesions are thought to result from somatic KRAS/BRAF mutations in brain endothelial cells (bECs). In this study, we introd...
Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) drives abnormal pericyte-rich vasculature in triple-negative breast cancer [0.03%]
细胞外烟酰胺单核苷酸磷酸 ribose 转移酶（eNAMPT）驱动三阴性乳腺癌中异常的周细胞血管生成
Marianna Moro,Federica Carolina Balestrero,Giorgia Colombo et al.
Marianna Moro et al.
Tumour angiogenesis supports malignant cells with oxygen and nutrients to promote invasion and metastasis. A number of cytokines released in situ participate in the recruitment of endothelial cells and pericytes to trigger the formation of ...
Study on mitogenic activity of serum from patients with total coronary occlusions: relation to duration of occlusion [0.03%]
完全闭塞患者血清促有丝分裂活性的研究-与闭塞持续时间的关系
V Tchaikovski,G S Werner,M Fritzenwanger et al.
V Tchaikovski et al.
In contrast to the extensive evidence from animal studies, only few human data are available on the relation of vascular growth factors and collateral function as well as on the conditions which may modify their release or function. In 31 p...
Retinal pigment epithelial cells reduce vascular leak and proliferation in retinal neovessels [0.03%]
视网膜色素上皮细胞减少视网膜新生血管的渗漏和增殖
Simone Tzaridis,Edith Aguilar,Michael I Dorrell et al.
Simone Tzaridis et al.
In multiple neurodegenerative diseases, including age-related macular degeneration, retinitis pigmentosa, and macular telangiectasia type 2 (MacTel), retinal pigment epithelial (RPE)-cells proliferate and migrate into the neuroretina, formi...
Correction: Mitochondrial control of hypoxia-induced pathological retinal angiogenesis [0.03%]
纠正：线粒体调控缺氧诱导的病理性视网膜新生血管形成
Hitomi Yagi,Myriam Boeck,Shen Nian et al.
Hitomi Yagi et al.
Published Erratum
Angiogenesis. 2024 Nov;27(4):701-702. DOI:10.1007/s10456-024-09952-6 2024
Dymonn Johnson,Sarah Colijn,Jahmiera Richee et al.
Dymonn Johnson et al.
Dynein cytoplasmic 1 light intermediate chain 1 (LIC1, DYNC1LI1) is a core subunit of the dynein motor complex. The LIC1 subunit also interacts with various cargo adaptors to regulate Rab-mediated endosomal recycling and lysosomal degradati...
Similarities and differences between brain and skin GNAQ p.R183Q driven capillary malformations [0.03%]
脑和皮肤GNAQ p.R183Q驱动的毛细血管畸形的相似性和差异性
Sana Nasim,Colette Bichsel,Anna Pinto et al.
Sana Nasim et al.
Capillary malformations (CM) are congenital vascular irregularities of capillary and venous blood vessels that appear in the skin, leptomeninges of the brain, and the choroid of the eye in the disorder known as Sturge Weber Syndrome (SWS). ...
Ryan D Makin,Ivana Apicella,Roshni Dholkawala et al.
Ryan D Makin et al.
Inflammasome activation is implicated in diseases of aberrant angiogenesis such as age-related macular degeneration (AMD), though its precise role in choroidal neovascularization (CNV), a characteristic pathology of advanced AMD, is ill-def...
Timed topical dexamethasone eye drops improve mitochondrial function to prevent severe retinopathy of prematurity [0.03%]
定时给予糖皮质激素滴眼液可改善早产儿视网膜病变的线粒体功能以预防增生性视网膜病变
Hitomi Yagi,Myriam Boeck,Mariya Petrishka-Lozenska et al.
Hitomi Yagi et al.
Pathological neovascularization in retinopathy of prematurity (ROP) can cause visual impairment in preterm infants. Current ROP treatments which are not preventative and only address late neovascular ROP, are costly and can lead to severe c...
The influences of ApoE isoforms on endothelial adherens junctions and actin cytoskeleton responding to mCRP [0.03%]
载脂蛋白E亚型影响mCRP诱导的血管内皮细胞黏着带和肌动蛋白细胞骨架重构的作用机制研究
Zhengrong Zhang,Weiwei Lin,Qini Gan et al.
Zhengrong Zhang et al.
Apolipoprotein E4 (ApoE4) plays an important role responding to monomeric C-reactive protein (mCRP) via binding to CD31 leading to cerebrovascular damage and Alzheimer's disease (AD). Using phosphor-proteomic profiling, we found altered cyt...