ApoM-bound S1P acts via endothelial S1PR1 to suppress choroidal neovascularization and vascular leakage [0.03%]
ApoM结合的S1P通过内皮细胞S1PR1抑制脉络膜新生血管和血管渗漏作用
Bongnam Jung,Hitomi Yagi,Andrew Kuo et al.
Bongnam Jung et al.
Neovascular age-related macular degeneration (nAMD) is a major cause of vision loss worldwide. Current standard of care is repetitive intraocular injections of vascular endothelial growth factor (VEGF) inhibitors, although responses may be ...
Endothelial USP11 drives VEGFR2 signaling and angiogenesis via PRDX2/c-MYC axis [0.03%]
内皮USP11通过PRDX2/c-MYC轴调控VEGFR2信号通路及促进血管生成
Can Chen,Zilong Chen,Ruijie Luo et al.
Can Chen et al.
Angiogenesis is a crucial component of various physiological and pathological processes, including embryonic development, ischemic diseases, and tumor progression. Recent studies have highlighted the importance of ubiquitinases in angiogene...
Endothelial transcriptomic, epigenomic and proteomic data challenge the proposed role for TSAd in vascular permeability [0.03%]
内皮转录组，表观基因组和蛋白质组数据挑战TSAd在血管通透性中的假定作用
James T Brash,Guillermo Diez-Pinel,Luca Rinaldi et al.
James T Brash et al.
The vascular endothelial growth factor VEGF drives excessive vascular permeability to cause tissue-damaging oedema in neovascular and inflammatory diseases across multiple organs. Several molecular pathways have been implicated in VEGF-indu...
Isolated human adipose microvessels retain native microvessel structure and recapitulate sprouting angiogenesis [0.03%]
人源性隔离脂肪微血管保持原有的微血管结构并再现了出芽型血管生成过程
Sarah M Moss,Thomas Gerton,Hannah A Strobel et al.
Sarah M Moss et al.
With interest growing in modeling more complex aspects of human disease in the laboratory, the need for effectively vascularizing human tissue models is becoming paramount. However, fully recreating human tissue microvasculatures is challen...
Immune-privileged cord blood-derived endothelial colony-forming cells: advancing immunomodulation and vascular regeneration [0.03%]
具有免疫特免优势的脐带血来源的内皮集落形成细胞：推动免疫调节与血管再生的发展
David M Smadja,Yanis Berkane,Nun K Bentounes et al.
David M Smadja et al.
Cord blood-derived endothelial colony-forming cells (CB-ECFCs) hold significant promise for regenerative medicine due to their unique vasculogenic and immunomodulatory properties. These cells exhibit a superior proliferative capacity, robus...
Correction: CCL4 contributes to aging related angiogenic insufficiency through activating oxidative stress and endothelial inflammation [0.03%]
纠正：CCL4通过激活氧化应激和内皮炎症而导致与年龄相关的血管生成不足
Ting-Ting Chang,Liang-Yu Lin,Ching Chen et al.
Ting-Ting Chang et al.
Published Erratum
Angiogenesis. 2025 Feb 28;28(2):18. DOI:10.1007/s10456-024-09964-2 2025
Cxcl9 modulates aging associated microvascular metabolic and angiogenic dysfunctions in subcutaneous adipose tissue [0.03%]
CXCL9调节皮下脂肪组织中与衰老相关的代谢和血管生成功能障碍
Xin Fu,Yu Zhao,Xiwei Cui et al.
Xin Fu et al.
Microvascular aging, predominantly driven by endothelial cells (ECs) dysfunction, is a critical early event in cardiovascular diseases. However, the specific effects of aging on ECs across the microvascular network segments and the associat...
Correction: Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions [0.03%]
Correction：神经纤毛蛋白-1通过相邻调节内皮细胞黏着带调控血管通透性
Sagnik Pal,Yangyang Su,Emmanuel Nwadozi et al.
Sagnik Pal et al.
Published Erratum
Angiogenesis. 2025 Feb 4;28(2):16. DOI:10.1007/s10456-024-09968-y 2025
From bench to bedside: murine models of inherited and sporadic brain arteriovenous malformations [0.03%]
从实验台到病床：遗传性和散发性脑动静脉畸形的小鼠模型
Ashely R Ricciardelli,Gael Genet,Nafiisha Genet et al.
Ashely R Ricciardelli et al.
Brain arteriovenous malformations are abnormal vascular structures in which an artery shunts high pressure blood directly to a vein without an intervening capillary bed. These lesions become highly remodeled over time and are prone to ruptu...