Tingting Yu,Qihang Yang,Bo Peng et al.
Tingting Yu et al.
Vascularized organoid-on-a-chip (VOoC) models achieve substance exchange in deep layers of organoids and provide a more physiologically relevant system in vitro. Common designs for VOoC primarily involve two categories: self-assembly of end...
2-Desaza-annomontine (C81) impedes angiogenesis through reduced VEGFR2 expression derived from inhibition of CDC2-like kinases [0.03%]
2-脱氮-annomontine（C81）通过抑制CDC2样激酶减少VEGFR2表达来阻碍血管生成
T J Zech,A Wolf,M Hector et al.
T J Zech et al.
Angiogenesis is a crucial process in the progression of various pathologies, like solid tumors, wet age-related macular degeneration, and chronic inflammation. Current anti-angiogenic treatments still have major drawbacks like limited effic...
Evidence of premature vascular dysfunction in young adults who regularly use e-cigarettes and the impact of usage length [0.03%]
定期使用电子烟的青年人早期血管功能障碍的证据及其使用时长的影响
Chloe Matheson,Tijana Simovic,Allison Heefner et al.
Chloe Matheson et al.
Background: Electronic (e-) cigarettes are increasingly popular tobacco products on the US market. Traditional tobacco products are known to cause vascular dysfunction, one of the earliest indicators of cardiovascular dis...
Sarah Dobner,Fanni Tóth,Laura P M H de Rooij
Sarah Dobner
Vascular endothelial cell (EC) aging has a strong impact on tissue perfusion and overall cardiovascular health. While studies confined to the investigation of aging-associated vascular readouts in one or a few tissues have already drastical...
People with a connective tissue disorder may be especially vulnerable to the endothelial damage that characterizes long COVID due to the fragility of their vasculature and slow wound healing [0.03%]
结缔组织疾病患者由于血管脆弱和伤口愈合缓慢，可能特别容易受到长COVID所导致的内皮损伤的影响。
Jeffrey Lubell
Jeffrey Lubell
A growing body of evidence documents the central role that endothelial damage plays in the pathophysiology of long COVID. But it remains unclear why only certain people get Long COVID and why recovery times are so long for many affected ind...
Impact of heterozygous ALK1 mutations on the transcriptomic response to BMP9 and BMP10 in endothelial cells from hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension donors [0.03%]
ALK1杂合突变对来自遗传性出血性动静脉畸形和肺动脉高压供体的内皮细胞中BMP9和BMP10转录组反应的影响
T Al Tabosh,H Liu,D Koça et al.
T Al Tabosh et al.
Heterozygous activin receptor-like kinase 1 (ALK1) mutations are associated with two vascular diseases: hereditary hemorrhagic telangiectasia (HHT) and more rarely pulmonary arterial hypertension (PAH). Here, we aimed to understand the impa...
Role of endothelial PDGFB in arterio-venous malformations pathogenesis [0.03%]
内皮细胞PDGFB在动静脉畸形发病机制中的作用
Yanzhu Lin,Johannes Gahn,Kuheli Banerjee et al.
Yanzhu Lin et al.
Arterial-venous malformations (AVMs) are direct connections between arteries and veins without an intervening capillary bed. Either familial inherited or sporadically occurring, localized pericytes (PCs) drop is among the AVMs' hallmarks. W...
Circulating Von Willebrand factor: a consistent biomarker predicting in-hospital mortality across different waves of the COVID-19 pandemic [0.03%]
循环Von Willebrand因子：一个在不同新冠疫情波次中持续预测住院死亡率的生物标志物
David M Smadja,Anne-Sophie Jannot,Aurélien Philippe et al.
David M Smadja et al.
Multimodality imaging reveals angiogenic evolution in vivo during calvarial bone defect healing [0.03%]
多模式影像学揭示颅骨缺损修复过程中新生血管的演变规律
Yunke Ren,Xinying Chu,Janaka Senarathna et al.
Yunke Ren et al.
The healing of calvarial bone defects is a pressing clinical problem that involves the dynamic interplay between angiogenesis and osteogenesis within the osteogenic niche. Although structural and functional vascular remodeling (i.e., angiog...
Correction: The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells [0.03%]
纠正：在内皮细胞中，血管发生抑制基因AKAP12处于HDAC7的表观遗传调控之下
Andrei Turtoi,Denis Mottet,Nicolas Matheus et al.
Andrei Turtoi et al.
Published Erratum
Angiogenesis. 2024 Feb;27(1):121-122. DOI:10.1007/s10456-023-09898-1 2024