Thirteenth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer [0.03%]
第十三届ENBDC研讨会：乳腺生物学和乳腺癌研究方法
Alecia-Jane Twigger,Jakub Sumbal,Mohamed Bentires-Alj et al.
Alecia-Jane Twigger et al.
The thirteenth annual workshop of the European Network for Breast Development and Cancer (ENBDC) Laboratories Annual Workshop took place on the 28-30 April 2022 in Weggis, Switzerland and focused on methods in mammary gland biology and brea...
Comparative Analysis of microRNAs that Stratify in vitro Mammary stem and Progenitor Activity Reveals Functionality of Human miR-92b-3p [0.03%]
通过比较体内乳腺干细胞和前体细胞活性分层的microRNAs揭示人类miR-92b-3p的功能性
James L Miller,Matt Kanke,Gat Rauner et al.
James L Miller et al.
Mammary stem/progenitor cells are fundamental for mammary gland development and function. However, much remains to be elucidated regarding their function in mammals beyond the traditionally studied rodents, human, and to a lesser extent, ru...
Comparative analysis of the molecular subtype landscape in canine and human mammary gland tumors [0.03%]
犬和人类乳腺肿瘤分子亚型谱系的比较分析
Helga Bergholtz,Tonje Lien,Frode Lingaas et al.
Helga Bergholtz et al.
Breast cancers in humans belong to one of several intrinsic molecular subtypes each with different tumor biology and different clinical impact. Mammary gland tumors in dogs are proposed as a relevant comparative model for human breast cance...
Induced mammary cancer in rat models: pathogenesis, genetics, and relevance to female breast cancer [0.03%]
大鼠乳腺癌模型的病因、遗传和女性乳腺癌的相关性
James L Miller,Arianna P Bartlett,Rebecca M Harman et al.
James L Miller et al.
Mammary cancer, or breast cancer in women, is a polygenic disease with a complex etiopathogenesis. While much remains elusive regarding its origin, it is well established that chemical carcinogens and endogenous estrogens contribute signifi...
Correction to: In Vivo Modeling of Human Breast Cancer Using Cell Line and Patient-Derived Xenografts [0.03%]
Correction to: 用人源性细胞系和患者来源的异种移植瘤开展活体人类乳腺癌模型研究
Eric P Souto,Lacey E Dobrolecki,Hugo Villanueva et al.
Eric P Souto et al.
Protein Tyrosine Phosphatase SHP2 Controls Interleukin-8 Expression in Breast Cancer Cells [0.03%]
蛋白酪氨酸磷酸酶SHP2调控乳腺癌细胞中的IL-8表达
Romain J Amante,Priska Auf der Maur,Veronica Richina et al.
Romain J Amante et al.
Treatment of metastasis remains a clinical challenge and the majority of breast cancer-related deaths are the result of drug-resistant metastases. The protein tyrosine phosphatase SHP2 encoded by the proto-oncogene PTPN11 promotes breast ca...
In Vivo Modeling of Human Breast Cancer Using Cell Line and Patient-Derived Xenografts [0.03%]
利用细胞系和患者来源的异种移植在体内模拟人类乳腺癌
Eric P Souto,Lacey E Dobrolecki,Hugo Villanueva et al.
Eric P Souto et al.
Historically, human breast cancer has been modeled largely in vitro using long-established cell lines primarily in two-dimensional culture, but also in three-dimensional cultures of varying cellular and molecular complexities. A subset of c...
Sodium Acetate and Sodium Butyrate Differentially Upregulate Antimicrobial Component Production in Mammary Glands of Lactating Goats [0.03%]
乙酸钠和丁酸钠差异性诱导泌乳山羊乳腺抗菌成分合成
Yusaku Tsugami,Naoki Suzuki,Takahiro Nii et al.
Yusaku Tsugami et al.
Short-chain fatty acids activate antimicrobial component production in the intestine. However, their effects on mammary glands remain unclear. We investigated the effects of acetate and butyrate on antimicrobial component production in mamm...
Adverse Effects of High Temperature On Mammary Alveolar Development In Vitro [0.03%]
高温对乳泡发育的不利影响（体外）
Haruka Wakasa,Yusaku Tsugami,Taku Koyama et al.
Haruka Wakasa et al.
In the mammary glands during pregnancy, the alveolar buds are first branched from the mammary ducts after which they form the alveolar luminal structure for milk production postparturition. Body temperature could increase for several reason...
Ductal Carcinoma in Situ: Molecular Changes Accompanying Disease Progression [0.03%]
导管原位癌的分子改变及其伴随疾病的进展
Gemma M Wilson,Phuong Dinh,Nirmala Pathmanathan et al.
Gemma M Wilson et al.
Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive ductal carcinoma (IDC), whereby if left untreated, approximately 12% of patients develop invasive disease. The current standard of care is surgical removal of the lesio...