FGFR2 Controls Growth, Adhesion and Migration of Nontumorigenic Human Mammary Epithelial Cells by Regulation of Integrin β1 Degradation [0.03%]
FGFR2通过调控整合素β1降解来控制非致瘤性人类乳腺上皮细胞的生长、粘附和迁移能力
Kamil Mieczkowski,Marta Popeda,Dagmara Lesniak et al.
Kamil Mieczkowski et al.
The role of fibroblast growth factor receptor 2 (FGFR2), an important mediator of stromal paracrine and autocrine signals, in mammary gland morphogenesis and breast cancer has been extensively studied over the last years. However, the funct...
Culture Models to Investigate Mechanisms of Milk Production and Blood-Milk Barrier in Mammary Epithelial Cells: a Review and a Protocol [0.03%]
用于研究乳腺上皮细胞产乳机制及血乳屏障的培养模型:综述与方案
Ken Kobayashi
Ken Kobayashi
Mammary epithelial cells (MECs) are the only cell type that produces milk during lactation. MECs also form less-permeable tight junctions (TJs) to prevent the leakage of milk and blood components through the paracellular pathway (blood-milk...
The Serotonergic System and Bone Metabolism During Pregnancy and Lactation and the Implications of SSRI Use on the Maternal-Offspring Dyad [0.03%]
妊娠和哺乳期血清素系统与骨代谢以及选择性5-羟色胺再摄取抑制剂使用对母子对的影响
Hannah P Fricke,Laura L Hernandez
Hannah P Fricke
Lactation is a physiological adaptation of the class Mammalia and is a product of over 200 million years of evolution. During lactation, the mammary gland orchestrates bone metabolism via serotonin signaling in order to provide sufficient c...
Associations Between Dog Breed and Clinical Features of Mammary Epithelial Neoplasia in Bitches: an Epidemiological Study of Submissions to a Single Diagnostic Pathology Centre Between 2008-2021 [0.03%]
2008年至2021年单个诊断病理中心提交的母狗乳腺上皮肿瘤与犬品种和临床特征的流行病学研究
Grace Edmunds,Sam Beck,Kedar Umakant Kale et al.
Grace Edmunds et al.
Mammary cancer is one of the most common neoplasms of dogs, primarily bitches. While studies have been carried out identifying differing risk of mammary neoplasia in different dog breeds, few studies have reported associations between dog b...
Correction to: Rank ectopic expression in the presence of Neu and PyMT oncogenes alters mammary epithelial cell populations and their tumorigenic potential [0.03%]
纠正:Rank异位表达在Neu和PyMT致癌基因存在下改变乳腺上皮细胞群体及其致瘤潜能
Alex Cordero,Patricia G Santamaría,Eva González-Suárez
Alex Cordero
Correction to: Valine Treatment Enhances Antimicrobial Component Production in Mammary Epithelial Cells and the Milk of Lactating Goats Without Influencing the Tight Junction Barrier [0.03%]
题为“缬氨酸处理增强山羊乳导管上皮细胞抗菌组分的生成而不影响紧密连接屏障”的正文的更正
Yusaku Tsugami,Takahiro Nii,Naoki Isobe
Yusaku Tsugami
Rank ectopic expression in the presence of Neu and MMTV oncogenes alters mammary epithelial cell populations and their tumorigenic potential [0.03%]
排名异位表达在神经和MMTV致癌基因存在下改变乳腺上皮细胞群体及其致瘤潜能
Alex Cordero,Patricia G Santamaría,Eva González-Suárez
Alex Cordero
Determination of the mammary epithelial cell that serves as the cell of origin for breast cancer is key to understand tumor heterogeneity and clinical management. In this study, we aimed to decipher whether Rank expression in the presence o...
Valine Treatment Enhances Antimicrobial Component Production in Mammary Epithelial Cells and the Milk of Lactating Goats Without Influencing the Tight Junction Barrier [0.03%]
缬氨酸处理可增强乳腺上皮细胞和泌乳山羊乳中抗菌组分的产生而不影响紧密连接屏障
Yusaku Tsugami,Takahiro Nii,Naoki Isobe
Yusaku Tsugami
The production of antimicrobial components and the formation of less-permeable tight junctions (TJs) are important in the defense system of lactating mammary glands and for safe dairy production. Valine is a branched-chain amino acid that i...
Characterization of Hyaluronan Localization in the Developing Mammary Gland and Mammary Tumors [0.03%]
透明质酸在发育期乳腺及乳腺肿瘤中的定位研究
Patrice M Witschen,Alexis K Elfstrum,Andrew C Nelson et al.
Patrice M Witschen et al.
The extracellular matrix (ECM) is biochemically and biomechanically important for the structure and function of the mammary gland, which undergoes vast structural changes throughout pubertal and reproductive development. Although hyaluronan...
Protein Expression of PI3K/AKT/mTOR Pathway Targets Validated by Gene Expression and its Correlation with Prognosis in Canine Mammary Cancer [0.03%]
PI3K/AKT/mTOR途径靶点的蛋白质表达及其基因表达与犬乳腺癌预后的相关性研究
Isabela F S Perossi,Mylena M Saito,Giovanna Rossi Varallo et al.
Isabela F S Perossi et al.
Mammary cancer is the main type of neoplasia in female dogs and is considered an adequate model for the biological and therapeutic study of cancer in women. The PIK3CA/AKT/mTOR pathway plays a central role in cellular homeostasis and is oft...