TGFß1 Stimulates Lymphatic Endothelial Cells to Produce IL7 and IL15, Which Act as Chemotactic Factors for Breast Cancer Cells with Mesenchymal Properties [0.03%]
TGFβ1刺激淋巴内皮细胞产生IL7和IL15，从而作为间质型乳腺癌细胞的趋化因子
Nikolina Giotopoulou,Wenyang Shi,Malgorzata Maria Parniewska et al.
Nikolina Giotopoulou et al.
The lymphatic system is a major gateway for tumor cell dissemination but the mechanisms of how tumor cells gain access to lymphatic vessels are not completely understood. Breast cancer cells undergoing epithelial-mesenchymal transition (EMT...
Marleen T Aarts,Muriel Wagner,Tanne van der Wal et al.
Marleen T Aarts et al.
Progesterone receptor (PR) signaling is required for mammary gland development and homeostasis. A major bottleneck in studying PR signaling is the lack of sensitive assays to measure and visualize PR pathway activity both quantitatively and...
High-fat diet, but not duration of lactation, increases mammary gland lymphatic vessel function and subsequent growth of inflammatory breast cancer cells [0.03%]
高脂肪饮食而非哺乳期的长短可增加乳腺淋巴管功能并促进炎性乳腺癌细胞随后生长
Wintana Balema,Janelle Morton,Richard A Larson et al.
Wintana Balema et al.
Inflammatory breast cancer (IBC) presents as rapid-onset swelling and breast skin changes caused by tumor emboli in the breast and breast skin lymphatics. IBC has been linked with obesity and duration of breastfeeding, but how these factors...
Fourteenth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer [0.03%]
第十四届ENBDC研讨会：乳腺生物学和乳腺癌研究方法
Silke Blair Chalmers,Tanne van der Wal,Silvia Fre et al.
Silke Blair Chalmers et al.
The fourteenth annual workshop of the European Network for Breast Development and Cancer (ENBDC) on Methods in Mammary Gland Biology and Breast Cancer was held on April 26th - 29th in Weggis, Switzerland. For the first time, early career re...
Non-Linear Lymphatic Anatomy in Breast Cancer Patients Prior to Axillary Lymph Node Dissection: A Risk Factor For Lymphedema Development [0.03%]
乳腺癌患者腋窝淋巴结活检前的非线性淋巴解剖结构是发生淋巴水肿的风险因素
JacqueLyn R Kinney,Rosie Friedman,Erin Kim et al.
JacqueLyn R Kinney et al.
Immediate lymphatic reconstruction (ILR) at the time of axillary lymph node dissection (ALND) has become increasingly utilized for the prevention of breast cancer related lymphedema. Preoperative indocyanine green (ICG) lymphography is rout...
Distinct Requirements for Adaptor Proteins NCK1 and NCK2 in Mammary Gland Development [0.03%]
NCK1和NCK2在乳腺发育中具有不同作用
Adam P Golding,Benjamin Ferrier,Laura A New et al.
Adam P Golding et al.
The adaptor proteins NCK1 and NCK2 are well-established signalling nodes that regulate diverse biological processes including cell proliferation and actin dynamics in many tissue types. Here we have investigated the distribution and functio...
Gestational Breast Cancer - a Review of Outcomes, Pathophysiology, and Model Systems [0.03%]
妊娠期乳腺癌——结局、病理生理和模型系统的综述
Mackenzie K Callaway,Camila O Dos Santos
Mackenzie K Callaway
The onset of pregnancy marks the start of offspring development, and represents the key physiological event that induces re-organization and specialization of breast tissue. Such drastic tissue remodeling has also been linked to epithelial ...
Studying Mammary Physiology and Pathology in Domestic Species Benefits Both Humans and Animals [0.03%]
家畜乳腺生理和病理学的研究造福人类和动物健康
Katherine Hughes
Katherine Hughes
Imagine beyond: recent breakthroughs and next challenges in mammary gland biology and breast cancer research [0.03%]
展望超越：乳腺生物学和乳腺癌研究中的近期突破及未来挑战
Renée van Amerongen,Mohamed Bentires-Alj,Antonius L van Boxtel et al.
Renée van Amerongen et al.
On 8 December 2022 the organizing committee of the European Network for Breast Development and Cancer labs (ENBDC) held its fifth annual Think Tank meeting in Amsterdam, the Netherlands. Here, we embraced the opportunity to look back to ide...
SFRP1 Expression is Inversely Associated With Metastasis Formation in Canine Mammary Tumours [0.03%]
SFRP1的表达与犬乳腺肿瘤转移形成的负相关关系
Judith Seitz,Alan Bilsland,Chloé Puget et al.
Judith Seitz et al.
Background: Canine mammary tumours (CMTs) are the most frequent tumours in intact female dogs and show strong similarities with human breast cancer. In contrast to the human disease there are no standardised diagnostic or...