Protocols for Co-Culture Phenotypic Assays with Breast Cancer Cells and THP-1-Derived Macrophages [0.03%]
乳腺癌细胞和THP-1来源的巨噬细胞共培养表型测定的protocol
Alicja Mazan,Anna A Marusiak
Alicja Mazan
Tumor mass comprises not only cancer cells but also heterogeneous populations of immune and stromal cells, along with the components of the extracellular matrix, collectively called the tumor microenvironment (TME). This diverse population ...
Fast Ultrasound Scanning is a Rapid, Sensitive, Precise and Cost-Effective Method to Monitor Tumor Grafts in Mice [0.03%]
快速超声扫描是一种监测小鼠肿瘤移植物的快速，敏感，精确和经济的方法
Sébastien Molière,Arthur Martinet,Amélie Jaulin et al.
Sébastien Molière et al.
In preclinical studies, accurate monitoring of tumor dynamics is crucial for understanding cancer biology and evaluating therapeutic interventions. Traditional methods like caliper measurements and bioluminescence imaging (BLI) have limitat...
Single-Cell Transcription Mapping of Murine and Human Mammary Organoids Responses to Female Hormones [0.03%]
小鼠和人乳腺类器官对雌性激素反应的单细胞转录图谱
Jenelys Ruiz Ortiz,Steven M Lewis,Michael Ciccone et al.
Jenelys Ruiz Ortiz et al.
During female adolescence and pregnancy, rising levels of hormones result in a cyclic source of signals that control the development of mammary tissue. While such alterations are well understood from a whole-gland perspective, the alteratio...
Toward Characterizing Lymphatic Vasculature in the Mammary Gland During Normal Development and Tumor-Associated Remodeling [0.03%]
正常发育和肿瘤相关重塑期间乳腺淋巴管结构的表征研究进展
Petra Dahms,Traci R Lyons
Petra Dahms
Lymphatic vasculature has been shown to promote metastatic spread of breast cancer. Lymphatic vasculature, which is made up of larger collecting vessels and smaller capillaries, has specialized cell junctions that facilitate cell intravasat...
Single-cell Analysis Reveals Inter- and Intratumour Heterogeneity in Metastatic Breast Cancer [0.03%]
单细胞分析揭示乳腺癌转移灶中瘤内和瘤间异质性
Baptiste Hamelin,Milan M S Obradović,Atul Sethi et al.
Baptiste Hamelin et al.
Metastasis is the leading cause of cancer-related deaths of breast cancer patients. Some cancer cells in a tumour go through successive steps, referred to as the metastatic cascade, and give rise to metastases at a distant site. We know tha...
TGFß1 Stimulates Lymphatic Endothelial Cells to Produce IL7 and IL15, Which Act as Chemotactic Factors for Breast Cancer Cells with Mesenchymal Properties [0.03%]
TGFβ1刺激淋巴内皮细胞产生IL7和IL15，从而作为间质型乳腺癌细胞的趋化因子
Nikolina Giotopoulou,Wenyang Shi,Malgorzata Maria Parniewska et al.
Nikolina Giotopoulou et al.
The lymphatic system is a major gateway for tumor cell dissemination but the mechanisms of how tumor cells gain access to lymphatic vessels are not completely understood. Breast cancer cells undergoing epithelial-mesenchymal transition (EMT...
Marleen T Aarts,Muriel Wagner,Tanne van der Wal et al.
Marleen T Aarts et al.
Progesterone receptor (PR) signaling is required for mammary gland development and homeostasis. A major bottleneck in studying PR signaling is the lack of sensitive assays to measure and visualize PR pathway activity both quantitatively and...
High-fat diet, but not duration of lactation, increases mammary gland lymphatic vessel function and subsequent growth of inflammatory breast cancer cells [0.03%]
高脂肪饮食而非哺乳期的长短可增加乳腺淋巴管功能并促进炎性乳腺癌细胞随后生长
Wintana Balema,Janelle Morton,Richard A Larson et al.
Wintana Balema et al.
Inflammatory breast cancer (IBC) presents as rapid-onset swelling and breast skin changes caused by tumor emboli in the breast and breast skin lymphatics. IBC has been linked with obesity and duration of breastfeeding, but how these factors...
Fourteenth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer [0.03%]
第十四届ENBDC研讨会：乳腺生物学和乳腺癌研究方法
Silke Blair Chalmers,Tanne van der Wal,Silvia Fre et al.
Silke Blair Chalmers et al.
The fourteenth annual workshop of the European Network for Breast Development and Cancer (ENBDC) on Methods in Mammary Gland Biology and Breast Cancer was held on April 26th - 29th in Weggis, Switzerland. For the first time, early career re...
Non-Linear Lymphatic Anatomy in Breast Cancer Patients Prior to Axillary Lymph Node Dissection: A Risk Factor For Lymphedema Development [0.03%]
乳腺癌患者腋窝淋巴结活检前的非线性淋巴解剖结构是发生淋巴水肿的风险因素
JacqueLyn R Kinney,Rosie Friedman,Erin Kim et al.
JacqueLyn R Kinney et al.
Immediate lymphatic reconstruction (ILR) at the time of axillary lymph node dissection (ALND) has become increasingly utilized for the prevention of breast cancer related lymphedema. Preoperative indocyanine green (ICG) lymphography is rout...