Anthony J Wilby,Sara Cabral,Nastaran Zoghi et al.
Anthony J Wilby et al.
Improved screening and treatment have decreased breast cancer mortality, although incidence continues to rise. Women at increased risk of breast cancer can be offered risk reducing treatments, such as tamoxifen, but this has not been shown ...
Kirsty Luo-Yng Tay,George Cowan,Subarnarekha Chatterji et al.
Kirsty Luo-Yng Tay et al.
How cancer patterns in humans compare to those of other species remains largely unknown and there is an even bigger knowledge gap for rare cancers like male breast cancer. One Health is a convergence of human and animal healthcare that enco...
Gat Rauner
Gat Rauner
This article offers a comprehensive perspective on the transformative role of organoid technology on mammary gland biology research across a diverse array of mammalian species.The mammary gland's unique development and regenerative capabili...
Traci R Lyons,Esta Sterneck
Traci R Lyons
Spatial Engineering of Mammary Epithelial Cell Cultures with 3D Bioprinting Reveals Growth Control by Branch Point Proximity [0.03%]
通过3D生物打印构建的乳腺上皮细胞培养的空间工程揭示了分支点 proximity 的生长控制
Leena M Koskinen,Lari Nieminen,Antti Arjonen et al.
Leena M Koskinen et al.
The three-dimensional (3D) structure of the ductal epithelium and the surrounding extracellular matrix (ECM) are integral aspects of the breast tissue, and they have important roles during mammary gland development, function and malignancy....
Protocols for Co-Culture Phenotypic Assays with Breast Cancer Cells and THP-1-Derived Macrophages [0.03%]
乳腺癌细胞和THP-1来源的巨噬细胞共培养表型测定的protocol
Alicja Mazan,Anna A Marusiak
Alicja Mazan
Tumor mass comprises not only cancer cells but also heterogeneous populations of immune and stromal cells, along with the components of the extracellular matrix, collectively called the tumor microenvironment (TME). This diverse population ...
Fast Ultrasound Scanning is a Rapid, Sensitive, Precise and Cost-Effective Method to Monitor Tumor Grafts in Mice [0.03%]
快速超声扫描是一种监测小鼠肿瘤移植物的快速，敏感，精确和经济的方法
Sébastien Molière,Arthur Martinet,Amélie Jaulin et al.
Sébastien Molière et al.
In preclinical studies, accurate monitoring of tumor dynamics is crucial for understanding cancer biology and evaluating therapeutic interventions. Traditional methods like caliper measurements and bioluminescence imaging (BLI) have limitat...
Single-Cell Transcription Mapping of Murine and Human Mammary Organoids Responses to Female Hormones [0.03%]
小鼠和人乳腺类器官对雌性激素反应的单细胞转录图谱
Jenelys Ruiz Ortiz,Steven M Lewis,Michael Ciccone et al.
Jenelys Ruiz Ortiz et al.
During female adolescence and pregnancy, rising levels of hormones result in a cyclic source of signals that control the development of mammary tissue. While such alterations are well understood from a whole-gland perspective, the alteratio...
Toward Characterizing Lymphatic Vasculature in the Mammary Gland During Normal Development and Tumor-Associated Remodeling [0.03%]
正常发育和肿瘤相关重塑期间乳腺淋巴管结构的表征研究进展
Petra Dahms,Traci R Lyons
Petra Dahms
Lymphatic vasculature has been shown to promote metastatic spread of breast cancer. Lymphatic vasculature, which is made up of larger collecting vessels and smaller capillaries, has specialized cell junctions that facilitate cell intravasat...
Single-cell Analysis Reveals Inter- and Intratumour Heterogeneity in Metastatic Breast Cancer [0.03%]
单细胞分析揭示乳腺癌转移灶中瘤内和瘤间异质性
Baptiste Hamelin,Milan M S Obradović,Atul Sethi et al.
Baptiste Hamelin et al.
Metastasis is the leading cause of cancer-related deaths of breast cancer patients. Some cancer cells in a tumour go through successive steps, referred to as the metastatic cascade, and give rise to metastases at a distant site. We know tha...