Johanna Englund,Zuzana Sumbalova Koledova
Johanna Englund
The collection on Methods and Models in Mammary Gland Biology and Breast Cancer Research showcases recent advances in tools and models that enhance our understanding of mammary gland development and breast cancer. This collection includes s...
Itamar Barash
Itamar Barash
Tumorigenesis in mammals is driven by inherited genetic variants, environmental factors and random errors during normal DNA replication that lead to cancer-causing mutations. These factors initiate uncontrolled cellular proliferation and di...
Recurrent Nipple Duct Obstruction in Two Breastfeeding Patients: A Case Report and Discussion of the Underlying Pathophysiology [0.03%]
两例哺乳期反复性乳管阻塞的病例报告及对潜在病理生理机制的讨论
Anna Sadovnikova,Susan Greenman,Bridget Young et al.
Anna Sadovnikova et al.
Nipple pain is a common reason for premature breastfeeding cessation. There exists anecdotal evidence that one cause of lactational nipple pain is a ductal obstruction, but there is no published literature describing this phenomenon. Herein...
Defective Mammary Epithelial Outgrowth in Transgenic EKAREV-NLS Mice: Correction via Estrogen Supplementation and Genetic Background Modification [0.03%]
转基因乳头状多瘤病毒EKA REV-NLS小鼠上皮外植体生成缺陷及通过雌激素补充和遗传背景改良进行纠正
Matea Brezak,Zuzana Sumbalova Koledova
Matea Brezak
Fluorescent biosensors offer a powerful tool for tracking and quantifying protein activity in living systems with high temporospatial resolution. However, the expression of genetically encoded fluorescent proteins can interfere with endogen...
Transcription Impairment of TMEM208 by ZBTB14 Suppresses Breast cancer Radiotherapy Resistance [0.03%]
TMEM208转录抑制剂ZBTB14可降低乳腺癌的放疗耐受性
Yan Li,Lili Liang
Yan Li
Zinc finger and BTB domain-containing protein (ZBTB) proteins have been implicated in different cellular processes, including DNA damage responses and cell cycle progression. However, the mechanism by which ZBTB14 modulates radiotherapy (RT...
15th Annual ENBDC Meeting: How do Cellular Potency, Microenvironment and Natural Rhythms Influence Mammary Gland Biology and Breast Cancer? [0.03%]
第十五届ENBDC会议：细胞活力，微环境和自然节律如何影响乳腺生物学和乳腺癌？
Maria Rafaeva,Beata Kaczyńska,Jaime Redondo-Pedraza et al.
Maria Rafaeva et al.
Following previous editions, the fifteenth annual workshop of the European Network for Breast Development and Cancer (ENBDC) on Methods in Mammary Gland Biology and Breast Cancer was held from the 2nd to the 4th of May in Weggis, Switzerlan...
Gestational breast cancer: distinctive molecular and clinico-epidemiological features [0.03%]
妊娠期乳腺癌：独特的分子和临床流行病学特征
J R de la Haba-Rodríguez,P Mínguez,F Rojo et al.
J R de la Haba-Rodríguez et al.
Gestational breast cancer (GBC), defined as breast cancer (BC) diagnosed during pregnancy or the first-year post-partum, accounts for 6-15% of BC cases in women aged 20-44 years. GBC has worse prognosis than non-GBC, but reasons behind are ...
Observational Study
Journal of mammary gland biology and neoplasia. 2024 Nov 8;29(1):18. DOI:10.1007/s10911-024-09571-3 2024
Maia N Machiela,Russell C Hovey
Maia N Machiela
Thymidine analogs such as ethynyl deoxyuridine (EdU) or bromodeoxyuridine (BrdU) can be used to label mitosis of mammary epithelial cells (MEC) and to quantify their proliferation. However, labeling cells in larger animals requires consider...
Ramiah Vickers,Weston Porter
Ramiah Vickers
Postpartum breast cancer (PPBC) is a unique subset of breast cancer, accounting for nearly half of the women diagnosed during their postpartum years. Mammary gland involution is widely regarded as being a key orchestrator in the initiation ...
Perimenopausal and Menopausal Mammary Glands In A 4-Vinylcyclohexene Diepoxide Mouse Model [0.03%]
4-乙烯基环己烯二氧模型小鼠围绝经期及绝经期乳腺的形态学变化
Kohei Saeki,Desiree Ha,Gregory Chang et al.
Kohei Saeki et al.
As both perimenopausal and menopausal periods are recognized critical windows of susceptibility for breast carcinogenesis, development of a physiologically relevant model has been warranted. The traditional ovariectomy model causes instant ...