Carlos Ronchi,Giovanna Ambrosini,Flavia Hughes et al.
Carlos Ronchi et al.
Developmental Regulation of circRNAs in Normal and Diseased Mammary Gland: A Focus on circRNA-miRNA Networks [0.03%]
正常和病变乳腺中circRNAs的发育调控：重点关注circRNA-miRNA网络
Sarah Marei,Nour Maatouk,Mounir AbouHaidar et al.
Sarah Marei et al.
Circular RNAs (circRNAs) have emerged as critical regulators in various biological processes including diseases. In the mammary gland (MG), which undergoes most of its development postnatally, circRNAs play pivotal roles in both physiologic...
Disease-Associated Mutations of the STAT5B SH2 Domain Regulate Cytokine-Driven Enhancer Function and Mammary Development [0.03%]
与疾病相关的STAT5B SH2结构域突变可调节细胞因子驱动的增强子功能和乳腺发育
Hye Kyung Lee,Jakub Jankowski,Chengyu Liu et al.
Hye Kyung Lee et al.
Mammary gland development during pregnancy is controlled by lactogenic hormones via the JAK2-STAT5 pathway. Gene deletion studies in mice have revealed the crucial roles of both STAT5A and STAT5B in establishing the genetic programs necessa...
Association of ESR1, HER1, and HER2 Polymorphisms with Breast Cancer Risk in the KP Population, A Case-Control Study [0.03%]
ESR1、HER1和HER2基因多态性与KP人群乳腺癌易感性的关联病例对照研究
Najeeb Ullah Khan,Hamza Khan,Abdullah R Alanzi et al.
Najeeb Ullah Khan et al.
Breast cancer is a complex disease characterized by the uncontrolled growth of breast cells. Genetic variants in ESR1, HER1, and HER2 have been associated with breast cancer risk across different populations, with varying results. This stud...
Buenos Aires Breast Cancer Symposium (BA-BCS 2024) A Second Successful "Trial" for Bringing Together both World Hemispheres To Debate the Future of Translational Breast Cancer Research [0.03%]
布宜诺斯艾利斯乳腺癌研讨会（BA-BCS 2024）：将全球两大半球聚集在一起，讨论乳腺癌转化研究未来的第二次成功“尝试”
Claudia Lanari,Virginia Novaro,Mario Rossi et al.
Claudia Lanari et al.
The second edition of the Buenos Aires Breast Cancer Symposium (BA-BCS), the first held in person, took place from September 3rd to 6th in Buenos Aires, Argentina. This report provides an overview of the talks delivered as individual lectur...
Johanna Englund,Zuzana Sumbalova Koledova
Johanna Englund
The collection on Methods and Models in Mammary Gland Biology and Breast Cancer Research showcases recent advances in tools and models that enhance our understanding of mammary gland development and breast cancer. This collection includes s...
Itamar Barash
Itamar Barash
Tumorigenesis in mammals is driven by inherited genetic variants, environmental factors and random errors during normal DNA replication that lead to cancer-causing mutations. These factors initiate uncontrolled cellular proliferation and di...
Recurrent Nipple Duct Obstruction in Two Breastfeeding Patients: A Case Report and Discussion of the Underlying Pathophysiology [0.03%]
两例哺乳期反复性乳管阻塞的病例报告及对潜在病理生理机制的讨论
Anna Sadovnikova,Susan Greenman,Bridget Young et al.
Anna Sadovnikova et al.
Nipple pain is a common reason for premature breastfeeding cessation. There exists anecdotal evidence that one cause of lactational nipple pain is a ductal obstruction, but there is no published literature describing this phenomenon. Herein...
Defective Mammary Epithelial Outgrowth in Transgenic EKAREV-NLS Mice: Correction via Estrogen Supplementation and Genetic Background Modification [0.03%]
转基因乳头状多瘤病毒EKA REV-NLS小鼠上皮外植体生成缺陷及通过雌激素补充和遗传背景改良进行纠正
Matea Brezak,Zuzana Sumbalova Koledova
Matea Brezak
Fluorescent biosensors offer a powerful tool for tracking and quantifying protein activity in living systems with high temporospatial resolution. However, the expression of genetically encoded fluorescent proteins can interfere with endogen...
Transcription Impairment of TMEM208 by ZBTB14 Suppresses Breast cancer Radiotherapy Resistance [0.03%]
TMEM208转录抑制剂ZBTB14可降低乳腺癌的放疗耐受性
Yan Li,Lili Liang
Yan Li
Zinc finger and BTB domain-containing protein (ZBTB) proteins have been implicated in different cellular processes, including DNA damage responses and cell cycle progression. However, the mechanism by which ZBTB14 modulates radiotherapy (RT...