CCND1 Amplification in Breast Cancer -associations With Proliferation, Histopathological Grade, Molecular Subtype and Prognosis [0.03%]
乳腺癌中CCND1拷贝数增加与增殖、组织病理学分级、分子亚型和预后之间的关系
Marit Valla,Elise Klæstad,Borgny Ytterhus et al.
Marit Valla et al.
CCND1 is located on 11q13. Increased CCND1 copy number (CN) in breast cancer (BC) is associated with high histopathological grade, high proliferation, and Luminal B subtype. In this study of CCND1 in primary BCs and corresponding axillary l...
Circ_0008500 Knockdown Improves Radiosensitivity and Inhibits Tumorigenesis in Breast Cancer Through the miR-758-3p/PFN2 Axis [0.03%]
circ_0008500通过miR-758-3p/PFN2轴提高乳腺癌放射敏感性并抑制肿瘤发生
Deyou Kong,Dongxing Shen,Zhikun Liu et al.
Deyou Kong et al.
Breast cancer is one of the most common malignancies worldwide. Circular RNAs (CircRNAs) were revealed to be implicated in the development of breast cancer. In this research, we aimed to investigate the role and underlying mechanism of circ...
Chronic Leptin Treatment Induces Epithelial-Mesenchymal Transition in MCF10A Mammary Epithelial Cells [0.03%]
慢性瘦素处理诱导MCF10A乳腺上皮细胞上皮间质转化
Juan Carlos Juárez-Cruz,Michal Okoniewski,Mónica Ramírez et al.
Juan Carlos Juárez-Cruz et al.
Leptin is a cytokine-like hormone that functions as a link between obesity and breast cancer (BC). Leptin treatment induces Epithelial to Mesenchymal Transition (EMT) in BC cell lines. In non-tumoral breast epithelial MCF10A cells, acute le...
Correction to: Peroxidasin Enhances Basal Phenotype and Inhibits Branching Morphogenesis in Breast Epithelial Progenitor Cell Line D492 [0.03%]
乳腺上皮干细胞系D492中过表达peroxidasin增强其基础表型并抑制支化形态发生（ correction ）
Anna Karen Sigurdardottir,Arna Steinunn Jonasdottir,Arni Asbjarnarson et al.
Anna Karen Sigurdardottir et al.
Decoding Insulin-Like Growth Factor Signaling Pathway From a Non-coding RNAs Perspective: A Step Towards Precision Oncology in Breast Cancer [0.03%]
从非编码RNA角度解码胰岛素样生长因子信号通路：迈向乳腺癌精准肿瘤学的一步
Yousra Ahmed ZeinElAbdeen,Amna AbdAlSeed,Rana A Youness
Yousra Ahmed ZeinElAbdeen
Breast cancer (BC) is a highly complex and heterogenous disease. Several oncogenic signaling pathways drive BC oncogenic activity, thus hindering scientists to unravel the exact molecular pathogenesis of such multifaceted disease. This high...
Short Term Changes in Dietary Fat Content and Metformin Treatment During Lactation Impact Milk Composition and Mammary Gland Morphology [0.03%]
哺乳期短期膳食脂肪含量变化和二甲双胍治疗影响乳汁组成和乳腺形态学
Zach Carlson,Hannah Hafner,Noura El Habbal et al.
Zach Carlson et al.
Maternal health and diet can have important consequences for offspring nutrition and metabolic health. During lactation, signals are communicated from the mother to the infant through milk via macronutrients, hormones, and bioactive molecul...
A CD8+ T Cell-Related Genes Expression Signature Predicts Prognosis and the Efficacy of Immunotherapy in Breast Cancer [0.03%]
一种CD8+T细胞相关基因表达谱可预测乳腺癌的预后及免疫治疗疗效
Lian-Hua Lv,Jia-Rong Lu,Tao Zhao et al.
Lian-Hua Lv et al.
Immunotherapy has been applied to patients with breast cancer. However, only part of patients benefits from the current immunotherapy. Accurate prediction of individual response to immunotherapy can be beneficial for breast cancer managemen...
Colostrogenesis: Role and Mechanism of the Bovine Fc Receptor of the Neonate (FcRn) [0.03%]
新生反刍动物肠壁上皮的发育：牛Fc受体(FcRn)的作用及其机制研究
Craig R Baumrucker,Ann L Macrina,Rupert M Bruckmaier
Craig R Baumrucker
Colostrogenesis is a separate and unique phase of mammary epithelial cell activity occurring in the weeks before parturition and rather abruptly ending after birth in the bovine. It has been the focus of research to define what controls thi...
Stromal Changes are Associated with High P4HA2 Expression in Ductal Carcinoma in Situ of the Breast [0.03%]
P4HA2在乳腺导管原位癌中的间质改变及临床意义
Marie Colombe Agahozo,Mieke van Bockstal,Pieter J Westenend et al.
Marie Colombe Agahozo et al.
Ductal carcinoma in situ (DCIS) of the breast is able to induce stromal changes, which likely reflect the crosstalk between DCIS and its microenvironment. These changes harbor prognostic information, although the interobserver variability o...
Local Heat Treatment of Goat Udders Influences Innate Immune Functions in Mammary Glands [0.03%]
山羊乳房局部热处理对其乳腺天然免疫功能的影响
Yusaku Tsugami,Yuki Ishiba,Naoki Suzuki et al.
Yusaku Tsugami et al.
Heat stress and mastitis adversely affect milk production in dairy ruminants. Although the udder temperature is elevated in both conditions, the influence of this local temperature rise on milk production and immune function of ruminant mam...