Neuroprotective Role of Morin Hydrate in Stress-Re-stress (SRS) Rat Model of PTSD: Mitigation of Cognitive Dysfunction, Anxiety, and Depression via Regulation of Oxidative Stress and Neuroinflammation [0.03%]
杨黄敏茋对PTSD应激-再应激(SRS)大鼠模型的神经保护作用：通过调节氧化应激和神经炎症缓解认知障碍、焦虑和抑郁
Sri Ram Mamidi,Ravi Chandra Sekhara Reddy Danduga
Sri Ram Mamidi
Post-traumatic stress disorder (PTSD) is a chronic psychiatric condition linked with abnormal fear responses, oxidative imbalance, inflammation, and neuronal injury. The present work examined the protective effects of morin hydrate (MH), a ...
Glibenclamide Attenuates Brain Edema After Intracerebral Hemorrhage Through Preservation of Blood-Brain Barrier Integrity and Glymphatic Function [0.03%]
格列本脲通过保存血脑屏障的完整性和胶质淋巴细胞的功能来缓解脑出血后的脑水肿
Chaonan Du,Yong Wu,Yuanming Geng et al.
Chaonan Du et al.
Astrocyte States in Brain Aging and Neurodegeneration: At the Crossroads of Senescence and Reactivity [0.03%]
星形胶质细胞在脑衰老和神经退行性疾病中的状态：衰老与反应性的交汇点
João Bastos Lima Pacca-Corrêa,Beatriz Martins Fernandes,Michele Siqueira et al.
João Bastos Lima Pacca-Corrêa et al.
Brain aging involves progressive disruption of tissue homeostasis and susceptibility to neurodegenerative disorders. Within this context, astrocytes are key determinants of region-specific physiology, given their roles in metabolic support,...
Intranasal Diazepam Outperforms Midazolam and Lorazepam in Early Seizure Control in Pilocarpine-Induced Mice Model [0.03%]
鼻用地西泮在毛果芸香碱诱导的小鼠模型中早期抗痫效能优于咪达唑仑和劳拉西epam
Anson Hei-Ka Tong,Jiajia Zhao,Jiahao Li et al.
Anson Hei-Ka Tong et al.
Epilepsy is a central nervous system disease characterized by the sudden onset of seizures, loss of consciousness, or confusion. In recent years, many non-intravenous routes of administration of benzodiazepines have been developed for seizu...
Comparative Study
Neurochemical research. 2026 Mar 5;51(2):101. DOI:10.1007/s11064-026-04720-y 2026
Antidepressant-like effect of hydroxytyrosol in a 1-methyl-4-phenylpyridinium model of Parkinson's disease in rats [0.03%]
橄榄茋在1-甲基-4-苯基吡啶
Gabriela Pérez-Barrón,Katia Sánchez-González,Silvia L Cruz et al.
Gabriela Pérez-Barrón et al.
Crocin Mitigates Glutamate Excitotoxicity and Tau Hyperphosphorylation by Modulating EAAT2 and Akt/Tau Pathway in a Scopolamine-induced Rat Model of Alzheimer's Disease [0.03%]
小活素通过调节EAAT2和Akt/Tau信号通路缓解天仙子胺诱导的阿尔茨海默病大鼠模型谷氨酸兴奋毒性及Tau蛋白过度磷酸化
Safinaz E El-Baga,Mohammed H Hassan,Eatemad A Awadalla et al.
Safinaz E El-Baga et al.
Alzheimer's disease (AD) is characterized by glutamatergic dysregulation and excitotoxicity, largely associated with impaired activity of the excitatory amino acid transporter 2 (EAAT2). Downregulation of EAAT2 results in glutamate accumula...
Analysis of Serum VCAN-AS1 Expression Level in Patients with Cerebral Infarction Secondary Epilepsy and Its Mechanism by Regulating miR-885-3p/NTNG1 [0.03%]
血管细胞粘连分子蛋白基因 antisense RNA 表达水平及其通过 miR-885-3p/NTNG1 轴调控机制在脑梗死后癫痫患者中的作用研究
Yang Lin,Kun Zhang,Meijie Zhang et al.
Yang Lin et al.
VCAN-AS1 is a novel long non-coding RNA that participates in diverse disease processes, but the mechanism of its action in cerebral infarction secondary epilepsy (CISE) is unclear. The potential action mechanism of VCAN-AS1 in CISE was expl...
Focal Estrogen Therapy in Male Rats Promotes Neuronal Survival and Reduces Denervation Atrophy After Spinal Cord Injury via Modulation of β-Catenin and NF-κB [0.03%]
雌激素焦距治疗通过调节β-连环蛋白和NF-κB促进雄性大鼠脊髓损伤后神经元存活和减少去神经萎缩
Azizul Haque,Vandana Zaman,Kelsey P Drasites et al.
Azizul Haque et al.
Berberine Attenuates Intracranial Aneurysm Formation by Activating SIRT1 to Suppress HMGB1 Acetylation and NF-κB Signaling [0.03%]
巴马汀通过激活SIRT1抑制HMGB1乙酰化和NF-κB信号通路以减少颅内动脉瘤形成
Jiacong Tan,Yanyang Zeng,Huaxin Zhu et al.
Jiacong Tan et al.
The formation of intracranial aneurysms (IAs) is linked to metabolic problems and functional abnormalities in vascular smooth muscle cells (VSMCs). Berberine (BBR), a tetracyclic alkaloid having anti-inflammatory, antioxidant, and energy me...
Single Intraperitoneal Injection of Dexamethasone Alerts Region-Specific Neurotransmitter Metabolism in Rat Brain [0.03%]
单剂量地塞米松腹腔注射引起大鼠脑区特异性神经递质代谢改变
Tatiana Valentinovna Tiutiunnik,Daria Alexeevna Obukhova,Valeria Andreevna Vilnikova et al.
Tatiana Valentinovna Tiutiunnik et al.
Synthetic glucocorticoids, such as dexamethasone, are widely used in therapy; however, their administration at high doses may be associated with effects on the central nervous system, particularly on neurotransmitter systems, yet the molecu...