The oligomeric subunit C rotor in the fo sector of ATP synthase: unresolved questions in our understanding of function [0.03%]
F1Fo-ATP合酶的Fo部分中的寡聚子C旋转环:C功能理解中悬而未决的问题
R H Fillingame,W Jiang,O Y Dmitriev
R H Fillingame
We have proposed a model for the oligomeric c-rotor of the F(o) sector of ATP synthase and its interaction with subunit a during H+-transport driven rotation. The model is based upon the solution structure of monomeric subunit c, determined...
ATP synthases in the year 2000: defining the different levels of mechanism and getting a grip on each [0.03%]
千禧年时期的ATP合成酶：界定不同层次的机制并掌握每种类型
P L Pedersen,Y H Ko,S Hong
P L Pedersen
ATP synthases are unusually complex molecules, which fractionate most readily into two major units, one a water soluble unit called F(1) and the other a detergent soluble unit called F(0). In almost all known species the F(1) unit consists ...
Proliferation of mitochondria in chronically stimulated rabbit skeletal muscle--transcription of mitochondrial genes and copy number of mitochondrial DNA [0.03%]
慢性刺激对兔骨骼肌线粒体增生的作用-线粒体基因的转录及线粒体DNA拷贝数的影响
J Schultz,R J Wiesner
J Schultz
Mitochondrial proliferation was studied in chronically stimulated rabbit skeletal muscle over a period of 50 days. After this time, subunits of COX had increased about fourfold. Corresponding mRNAs, encoded on mitochondrial DNA as well as o...
Evidence for a conformational change in subunit III of bovine heart mitochondrial cytochrome c oxidase [0.03%]
牛心线粒体细胞色素c氧化酶亚基III构象变化的证据
E O Ogunjimi,C N Pokalsky,L A Shroyer et al.
E O Ogunjimi et al.
The role of subunit III in the function of mitochondrial cytochrome c oxidase is not clearly understood. Previous work has shown that chemical modification of subunit III with N,N'-dicyclohexylcarbodiimide (DCCD) reduced the proton-pumping ...
Localization of the site of oxygen radical generation inside the complex I of heart and nonsynaptic brain mammalian mitochondria [0.03%]
心脏和非突触脑哺乳动物线粒体中复合物I内生成氧自由基位点的定位
A Herrero,G Barja
A Herrero
Mitochondrial production of oxygen radicals seems to be involved in many diseases and aging. Recent studies clearly showed that a substantial part of the free radical generation of rodent mitochondria comes from complex I. It is thus import...
Modulation at a distance of proton conductance through the Saccharomyces cerevisiae mitochondrial F1F0-ATP synthase by variants of the oligomycin sensitivity-conferring protein containing substitutions near the C-terminus [0.03%]
寡霉素敏感性传导蛋白的远距离调制作用及其C端附近含有替代物的变异体通过酵母线粒体F1F0-ATP合酶实现质子传导性调节
G M Boyle,X Roucou,P Nagley et al.
G M Boyle et al.
We have sought to elucidate how the oligomycin sensitivity-conferring protein (OSCP) of the mitochondrial F(1)F(0)-ATP synthase (mtATPase) can influence proton channel function. Variants of OSCP, from the yeast Saccharomyces cerevisiae, hav...
Characterization of channel-forming activity in muscle biopsy from a porin-deficient human patient [0.03%]
PORIN缺乏患者的肌肉活检标本的通道形成活性的特征研究
V De Pinto,A Messina,A Schmid et al.
V De Pinto et al.
A bioptic specimen from the muscles of a patient suffering from severe myopathy was inspected for the presence of human porin 31HL. Western blotting suggested that the specimen was free of the most abundant eukaryotic porin 31HL (HVDAC1). T...
Modulation of the voltage-dependent anion channel (VDAC) by glutamate [0.03%]
谷氨酸对电压依赖性阴离子通道(VDAC)的调节作用
D Gincel,S D Silberberg,V Shoshan-Barmatz
D Gincel
The voltage-dependent anion channel (VDAC), also known as mitochondrial porin, is a large channel permeable to anions, cations, ATP, and other metabolites. VDAC was purified from sheep brain synaptosomes or rat liver mitochondria using a re...
Functional characterization of the conserved "GLK" motif in mitochondrial porin from Neurospora crassa [0.03%]
模式真菌Neurospora crassa线粒体porin保守的"GLK"基序的功能分析
G Runke,E Maier,J D O&#x;Neil et al.
G Runke et al.
Mitochondrial porin facilitates the diffusion of small hydrophilic molecules across the mitochondrial outer membrane. Despite low sequence similarity among porins from different species, a "glycine-leucine-lysine" (GLK) motif is conserved i...
Occurrence of plant-uncoupling mitochondrial protein (PUMP) in diverse organs and tissues of several plants [0.03%]
几种植物的不同器官和组织中存在植物型解偶联线粒体蛋白(PUMP)
P Jezek,M Zácková,J Kosarová et al.
P Jezek et al.
The presence of plant-uncoupling mitochondrial protein (PUMP), previously described by Vercesi et al. (1995), was screened in mitochondria of various organs or tissues of several plant species. This was done functionally, by monitoring puri...