Interplay Between Autophagy, Cellular Senescence, and Brain Aging: Neuroprotective Implications of Intermittent Fasting [0.03%]
自噬、细胞衰老和大脑老化之间的相互作用及间歇性禁食的神经保护意义
Ishika Singh,Shreya Bhat,Rajesh Tamatta et al.
Ishika Singh et al.
Peripheral Inflammatory Biomarkers in Parkinson's Disease: Clinical Correlations and Stratification [0.03%]
帕金森病的外周炎性生物标志物：临床相关性和分层分析
Guo-Yun Jiang,Fan Li,Jin-Hui Yin et al.
Guo-Yun Jiang et al.
Growing evidence underscores neuroinflammation's role in Parkinson's disease (PD), with accumulating evidence suggesting a potential role for peripheral inflammation. The clinical applicability and mechanistic relevance of peripheral inflam...
Nitric Oxide Donor Alleviates Cardiac Arrest Induced Blood Brain Barrier Injury by Inhibiting HMGB1-ATG5 Mediated Endothelial [0.03%]
一氧化氮供体通过抑制HMGB1-ATG5介导的内皮细胞焦亡减轻心肺复苏后血脑屏障损伤
Pengyu Duan,Yonghong Bi,Weiyu Feng et al.
Pengyu Duan et al.
Investigating the Regulatory Mechanisms and Prognostic Significance of miR-941 Targeting the Nrf2/Keap1 Pathway in Elderly Ischemic Stroke Patients [0.03%]
miR-941靶向Nrf2/Keap1通路在老年缺血性卒中患者中的调控机制及预后意义研究
Xixia Huang,Jianpeng Gao,Rongbin Zhu et al.
Xixia Huang et al.
This study aims to explore the role and underlying correlation of miR-941 in the targeted regulation of the Keap1/Nrf2 signaling pathway in the prognosis of senile ischemic stroke (IS), providing new targets and strategies for clinical trea...
Decoding the Glioblastoma Microenvironment: AI-Driven Analysis of Cellular MRI Signatures for Targeted Therapy [0.03%]
解码胶质母细胞瘤微环境：基于人工智能的细胞MRI特征分析以实现靶向治疗
Yao Sun,Kai Wang,Tiantao Ye
Yao Sun
Glioblastoma (GB), the most aggressive primary brain tumor, is characterized by profound inter- and intratumoral heterogeneity and a highly immunosuppressive tumor microenvironment (TME), both of which contribute to its poor prognosis and r...
Sex-Dependent Dynamics of Behavioural and Neuropathological Changes in an A53T Alpha-Synuclein Mouse Model of Parkinson's Disease [0.03%]
帕金森病A53Tα-突触核蛋白小鼠模型的行为和神经病理学改变的性别依赖动力学特征研究
Maider Zubelzu,Raphaelle Bidgood,Ane Murueta-Goyena et al.
Maider Zubelzu et al.
A Dopamine D1-Like Receptor Agonist Ameliorates Traumatic Brain Injury Through its Immunosuppressive Effects [0.03%]
多巴胺D1受体激动剂通过免疫抑制作用改善创伤性脑损伤
Mohammed E Choudhury,Ayane Takenaga,Haruto Yamamoto et al.
Mohammed E Choudhury et al.
Traumatic brain injury (TBI) causes progressive nervous tissue degeneration long after the initial injury due to secondary neuroinflammatory reactions. G protein-coupled dopamine D1-like receptors, which elevate intracellular cAMP levels, h...
Neuroradiological Phenotype Expansion of the Siddiqi Syndrome: A Case Report [0.03%]
赛迪奇综合症的神经影像表型扩展：一例报道
Paula Trilla,Laia Rodriguez-Revenga,Aurora Sanchez et al.
Paula Trilla et al.
Siddiqi syndrome is a rare autosomal recessive deafness-dystonia disorder caused by pathogenic variants in the FITM2 gene. To date, only 5 unrelated families have been reported in the literature carrying loss-of-function variants in FIMT2 g...
The Double-Edged Sword Effect of the Fibrinolytic System in Alzheimer's Disease [0.03%]
纤溶系统在阿尔茨海默病中的双刃剑效应
Mingqing Tang,Meimei Liang,Xianying Zhang et al.
Mingqing Tang et al.
Alzheimer's disease (AD), the most prevalent neurodegenerative disorder, is fundamentally driven by dysregulation between amyloid-β (Aβ) production and clearance. Although multiple Aβ clearance pathways have been reported, the fibrinolyt...
D-serine: A Multitalented Neuromodulator in Brain Function, Systemic Homeostasis, and Disease [0.03%]
D-丝氨酸：一种在脑功能、全身稳态和疾病中的多功能神经调质
Jing Wang,Yujin Guo,Wenxiu Han et al.
Jing Wang et al.