Increased cerebral oxidative damage and decreased antioxidant defenses in ovariectomized and sham-operated rats supplemented with vitamin A [0.03%]
卵巢切除及假手术大鼠维生素A补充对脑氧化应激的影响研究
Guilherme Antonio Behr,Carlos Eduardo Schnorr,André Simões-Pires et al.
Guilherme Antonio Behr et al.
Previous studies have linked oxidative stress with aging and aging-related processes, including menopause. Abnormalities in the redox state similar to those observed in menopausal women can be modeled experimentally with rat ovariectomy. Th...
The multidrug resistance protein breast cancer resistance protein (BCRP) protects adipose-derived stem cells against ischemic damage [0.03%]
多药耐药蛋白乳腺癌耐药蛋白（BCRP）保护脂肪源性干细胞免受缺血损伤
A van Dijk,B A Naaijkens,W J F M Jurgens et al.
A van Dijk et al.
Adipose tissue-derived stem cells (ASCs) are promising candidates for regenerative therapy, like after myocardial infarction. However, when transplanted into the infarcted heart, ASCs are jeopardized by the ischemic environment. Interesting...
The effect of culture conditions on colony morphology and proliferative capacity in human prostate cancer cell lines [0.03%]
培养条件对人前列腺癌细胞系菌落形态和增殖能力的影响
Charlotte M Beaver
Charlotte M Beaver
Primary cultures and cell lines form three types of colonies, termed holoclones, meroclones and paraclones by Barrandon and Green (Proc Natl Acad Sci U S A 84:2302-2306, 1987). They suggested that the three types correspond to colonies deri...
The epithelial sodium channel is involved in dexamethasone-induced osteoblast differentiation and mineralization [0.03%]
上皮钠通道参与地塞米松诱导的成骨细胞分化和矿化作用
Li Lu,Liang Wu,Huanhuan Jia et al.
Li Lu et al.
Purpose: Glucocorticoids (GCs) can facilitate bone formation, but prolonged GCs exposure in vivo can lead to osteoporosis. The mechanisms underlying these reciprocal effects have not been elucidated. ...
Toll-like receptor 4 ligation confers chemoresistance to docetaxel on PC-3 human prostate cancer cells [0.03%]
TLR4介导的信号转导使前列腺癌PC-3细胞产生多西他赛耐药性
Yuntao Zhang,Yong Wang,Jianlin Yuan et al.
Yuntao Zhang et al.
Recent studies have indicated that Toll-like receptors (TLRs) are implicated in the development of chemoresistance in cancer cells. TLR4 has been shown to be highly expressed in prostate cancer cells and contributes to tumor cell survival a...
The role of ribosylated-BSA in regulating PC12 cell viability [0.03%]
ribosylated-bsa在调节PC12细胞活力中的作用
Tsun-Yung Kuo,Chuen-Lin Huang,Jung-Mou Yang et al.
Tsun-Yung Kuo et al.
Glycation, one of the post-translational modifications, is known to influence protein structure and biological function. Advanced glycation end products (AGEs) have been shown to cause pathologies of diabetes. Glycation levels in patients w...
Differential effects of Bcl-2 and caspases on mitochondrial permeabilization during endogenous or exogenous reactive oxygen species-induced cell death: a comparative study of H₂O₂, paraquat, t-BHP, etoposide and TNF-α-induced cell death [0.03%]
Bcl-2和半胱天冬酶对内源性和外源性活性氧诱导的线粒体膜通透性转换的不同作用：H₂O₂、Paraquat、t-BHP、Etoposide和TNF-α凋亡的比较研究
Vincent Rincheval,Marie Bergeaud,Lise Mathieu et al.
Vincent Rincheval et al.
In this study, we have compared several features of cell death triggered by classical inducers of apoptotic pathways (etoposide and tumour necrosis factor (TNF)-α) versus exogenous reactive oxygen species (ROS; hydrogen peroxide (H₂O₂), ...
Comparative Study
Cell biology and toxicology. 2012 Aug;28(4):239-53. DOI:10.1007/s10565-012-9219-9 2012
Differential response of three cell types to dual stress of nitric oxide and radiation [0.03%]
一氧化氮和放射联合刺激对三种细胞类型的不同响应
Fatema A Dhariwala,Himanshi Narang,Malini Krishna
Fatema A Dhariwala
The perception of toxicity to nitric oxide (NO) and irradiation (IR) by three different cell types has been studied. The three cell types are the macrophage like RAW264.7 cells, EL4 lymphoma cells, and splenocytes, which represent the diffe...
Effects of clothianidin exposure on sperm quality, testicular apoptosis and fatty acid composition in developing male rats [0.03%]
噻虫胺对大鼠睾丸脂肪酸组成和精子质量的影响及作用机制研究
Ramazan Bal,Gaffari Türk,Ökkeş Yılmaz et al.
Ramazan Bal et al.
Clothianidin (CTD) is one of the latest members of the synthetic organic insecticides, the neonicotinoids. In the present study, it was aimed to investigate if daily oral administration of CTD at low doses for 90 days has any deleterious ef...
Toshihiko Aki,Akina Nara,Koichi Uemura
Toshihiko Aki
Cytoplasmic vacuolization upon exposure to a variety of chemicals and bioactive substances has been extensively reported. Nearly 30 years have passed since the description by Nobel Laureate Christian de Duve of the mechanism underlying the ...