Activation of alternative metabolic pathways diverts carbon flux away from isobutanol formation in an engineered Escherichia coli strain [0.03%]
乙醇梭菌途径工程菌中激活替代代谢途径导致碳流量偏离异丁醇生成路径
Shalini S Deb,Shamlan M S Reshamwala,Arvind M Lali
Shalini S Deb
Objective: Metabolic engineering efforts are guided by identifying gene targets for overexpression and/or deletion. Isobutanol, a biofuel candidate, is biosynthesized using the valine biosynthesis pathway and enzymes of t...
Pseudomonas monteilii PN1: a great potential P-nitrophenol degrader with plant growth promoting traits under drought and saline-alkali stresses [0.03%]
芽孢杆菌PN1：一种具有植物生长促进性状的P-硝基苯酚降解菌，在干旱和盐碱胁迫下的巨大潜力
Yuqin Zhang,Feng Yang,Hejun Ren et al.
Yuqin Zhang et al.
Objectives: To evaluate Pseudomonas monteilii strain PN1 for the removal efficiency of P-nitrophenol (PNP) in soils and its growth promotion of maize (Zea mays L.) seedlings under drought and saline-alkali stress. ...
GC-MS based profiling of alkanes in the filamentous yeast Hyphozyma roseoniger (Moesziomyces antarcticus) [0.03%]
基于GC-MS的棒曲霉（莫兹伊丝安达弗斯棒曲霉）中烷烃定性定量分析
Efficient N Ncube,Lucia Steenkamp,Ian A Dubery
Efficient N Ncube
Objectives: Hyphozyma roseoniger, a filamentous yeast, is used as a biocatalyst in the bio-transformation of terpenoids; however, the microorganism's endogenous ability to synthesise and metabolise hydrophobic terpenes an...
MiR-499 inhibited hypoxia/reoxygenation induced cardiomyocytes injury by targeting SOX6 [0.03%]
miR-499通过靶向SOX6抑制缺氧/复氧诱导的心肌细胞损伤
Yujie Shi,Yunfeng Han,Lili Niu et al.
Yujie Shi et al.
Objective: MiR-499 has been reported to be expressed only in cardiomyocytes, and its expression would increase after acute myocardial infarction (AMI). miR-499 plays a role in the process of cardiomyocytes injury induced ...
Multiphosphorylation and cellular localization of poly(rC) binding protein 1 during mitosis in hela cell [0.03%]
HeLa细胞有丝分裂过程中poly(rC)结合蛋白1的多磷酸化及其亚细胞定位
Xiang Ma,Huicai Li,Xue Cao et al.
Xiang Ma et al.
Objective: To monitor the phosphorylation modifications and cellular localization of poly(rC)-binding protein-1 (PCBP1) during the cell cycle progression of Hela cells. ...
Pharmacological Notch pathway inhibition leads to cell cycle arrest and stimulates ascl1 and neurogenin2 genes expression in dental pulp stem cells-derived neurospheres [0.03%]
药理学诺特定向抑制导致细胞周期停滞并刺激牙髓干细胞诱导的类神经球中ascl1和neurogenin2基因表达
Ali Niapour,Hatef Ghasemi Hamidabadi,Nazila Niapour et al.
Ali Niapour et al.
Objective: Human dental pulp-derived stem cells (hDPSCs) are becoming an attractive source for cell-based neurorestorative therapies. As such, it is important to understand the molecular mechanisms that regulate the diffe...
Biocatalytic synthesis and characterization of sn-1/3 and sn-2 monoacylglycerols [0.03%]
生物催化剂合成和表征sn-1/3和sn-2单酰基甘油
Xiuwen Wang,Yang Cheng,Qingzhe Jin et al.
Xiuwen Wang et al.
Objectives: To investigate the lipase-catalyzed synthesis of high purity sn-1/3 and sn-2 monoacylglycerols (1/3-MAG and 2-MAG) of different fatty acids (FAs). ...
Precursor-feeding and altered-growth conditions reveal novel blue pigment production by Rubrivivax benzoatilyticus JA2 [0.03%]
前体补料和改变培养条件可使Rubrivivax benzoatilyticus JA2产生新型蓝色色素
Lakshmi Prasuna Mekala,Mujahid Mohammed,Sasikala Chintalapati et al.
Lakshmi Prasuna Mekala et al.
Objective: To explore the secondary metabolite biosynthetic potential of Rubrivivax benzoatilyticus JA2 using a new metabolite mining strategy. Results: ...
The impact of N-terminal nonessential domains on the enzymological properties of the pullulanase from a marine Bacillus megaterium [0.03%]
N端非本质结构域对海洋芽孢杆菌普鲁兰酶酶学性质的影响
YuLiang Jiao,Yong Wu,HongXu Chen et al.
YuLiang Jiao et al.
Objective: To determine the impact of the N-terminal nonessential domains on the enzymological properties of a pullulanase (BmP) from Bacillus megaterium strain P6. ...
Engineering CHO cells galactose metabolism to reduce lactate synthesis [0.03%]
工程改造CHO细胞半乳糖代谢以减少乳酸合成
N Jiménez,V S Martínez,Z P Gerdtzen
N Jiménez
Objective: Over-express galactokinase (Galk1) in tissue plasminogen activator (tPA) producing CHO cells as a potential strategy to improve cell growth and product synthesis. ...