NMR structure note: repetitive domain of aciniform spidroin 1 from Nephila antipodiana [0.03%]
重复域的核磁共振结构注释：来自Nephilafantipodiana的AciniformSpidroin1蛋白质
Shujing Wang,Weidong Huang,Daiwen Yang
Shujing Wang
Accuracy and precision of protein-ligand interaction kinetics determined from chemical shift titrations [0.03%]
化学位移滴定确定的蛋白质-配体相互作用动力学的准确性和精确性
Craig J Markin,Leo Spyracopoulos
Craig J Markin
NMR-monitored chemical shift titrations for the study of weak protein-ligand interactions represent a rich source of information regarding thermodynamic parameters such as dissociation constants (K ( D )) in the micro- to millimolar range, ...
Spectral editing of two-dimensional magic-angle-spinning solid-state NMR spectra for protein resonance assignment and structure determination [0.03%]
用于蛋白质共振赋值和结构测定的二维魔角旋转固态NMR谱的光谱编辑
K Schmidt-Rohr,K J Fritzsching,S Y Liao et al.
K Schmidt-Rohr et al.
Several techniques for spectral editing of 2D (13)C-(13)C correlation NMR of proteins are introduced. They greatly reduce the spectral overlap for five common amino acid types, thus simplifying spectral assignment and conformational analysi...
Cell signaling, post-translational protein modifications and NMR spectroscopy [0.03%]
细胞信号转导、蛋白质修饰和核磁共振光谱技术
Francois-Xavier Theillet,Caroline Smet-Nocca,Stamatios Liokatis et al.
Francois-Xavier Theillet et al.
Post-translationally modified proteins make up the majority of the proteome and establish, to a large part, the impressive level of functional diversity in higher, multi-cellular organisms. Most eukaryotic post-translational protein modific...
Improved chemical shift prediction by Rosetta conformational sampling [0.03%]
通过Rosetta构象采样改进化学位移预测能力
Ye Tian,Stanley J Opella,Francesca M Marassi
Ye Tian
Chemical shift frequencies represent a time-average of all the conformational states populated by a protein. Thus, chemical shift prediction programs based on sequence and database analysis yield higher accuracy for rigid rather than flexib...
NMR characterization of the C-terminal tail of full-length RAGE in a membrane mimicking environment [0.03%]
全长度RAGE在模拟膜环境中的C端尾部的NMR表征
Valentina Borsi,Linda Cerofolini,Marco Fragai et al.
Valentina Borsi et al.
Targeting the receptor for the advanced glycation endproducts (RAGE) signalling has a potential for the prevention and treatment of several pathologies. Extracellular activation of RAGE triggers the interactions of the RAGE cytoplasmic tail...
The description of protein internal motions aids selection of ligand binding poses by the INPHARMA method [0.03%]
描述蛋白质内部运动有助于INPHARMA方法选择配体结合构象
Benjamin Stauch,Julien Orts,Teresa Carlomagno
Benjamin Stauch
Protein internal motions influence observables of NMR experiments. The effect of internal motions occurring at the sub-nanosecond timescale can be described by NMR order parameters. Here, we report that the use of order parameters derived f...
Solid-state NMR analysis of membrane proteins and protein aggregates by proton detected spectroscopy [0.03%]
利用氢检测固态NMR分析膜蛋白和蛋白质聚集体
Donghua H Zhou,Andrew J Nieuwkoop,Deborah A Berthold et al.
Donghua H Zhou et al.
Solid-state NMR has emerged as an important tool for structural biology and chemistry, capable of solving atomic-resolution structures for proteins in membrane-bound and aggregated states. Proton detection methods have been recently realize...
NMR structure note: solution structure of human Miz-1 zinc fingers 8 to 10 [0.03%]
人源Miz-1锌指8到10的溶液结构注解
Mikaël Bédard,Loïka Maltais,Marie-Eve Beaulieu et al.
Mikaël Bédard et al.
CING: an integrated residue-based structure validation program suite [0.03%]
CING：一个集成的基于残基的结构验证程序套件
Jurgen F Doreleijers,Alan W Sousa da Silva,Elmar Krieger et al.
Jurgen F Doreleijers et al.
We present a suite of programs, named CING for Common Interface for NMR Structure Generation that provides for a residue-based, integrated validation of the structural NMR ensemble in conjunction with the experimental restraints and other i...