A Label-free Simple Biosensor for Pb2+ Detection Based on G-quadruplex DNA and Exonuclease III [0.03%]
一种基于G-四链体DNA和外切酶III的无标签Pb2+检测生物传感器
Xingping Zhang,Yu Peng,Shengxin Wen et al.
Xingping Zhang et al.
Lead ions (Pb2+), as heavy metal ions, pose significant hazards to human health. Therefore, it is of great significance to establish a simple and effective method for detecting Pb2+. In this study, a label-free Pb2+ biosensor was establishe...
From Golden Berry To Golden Nanoprobe: Sustainable Fluorescent Sensing of Torsemide For Doping Control in Athletes [0.03%]
从黄金浆果到黄金纳米探针：可持续荧光检测运动员体内托塞米的兴奋剂检测方法
Alaa Ahmed Mostafa,Soad S Abd El-Hay,Michael Gamal Fawzy et al.
Alaa Ahmed Mostafa et al.
Doping represents a critical threat to the integrity of competitive sports, with diuretics frequently misused as masking agents to facilitate the urinary excretion of other prohibited substances. Torsemide (TSD), a widely misused loop diure...
Concurrent Enhancement of Aggregation-induced Emission and Two-photon Absorption in Symmetric Naphthalimide Derivatives via Methoxy Substitution [0.03%]
通过甲氧基取代在对称萘酰亚胺衍生物中同时增强聚集诱导发光和双光子吸收性能
Xue Sun,Ying Bao,Haoran Ni et al.
Xue Sun et al.
In this work, bisNAPTPA and its derivative bisNAPTPA-OCH3 have been investigated to reveal how targeted methoxy substitution tunes the photophysical properties in symmetric naphthalimide derivatives. Combined experimental and theoretical an...
Recent Advances in the ESIPT-based Responsive Probes for the Detection of Bio-Active Molecules CO, NO and H₂S [0.03%]
近期基于ESIPT的响应型探针在检测生物活性分子CO、NO和H2S领域的进展
Hossein Roohi
Hossein Roohi
Excited-state intramolecular proton transfer (ESIPT)-based fluorescent probes have emerged as powerful tools for bioimaging and chemical sensing owing to their large Stokes shifts, dual-emission characteristics, high sensitivity, and reduce...
Engineering Mono- to Trimetallic Nanoclusters for Next-Generation Luminescence Sensing of Narcotic Drugs [0.03%]
用于下一代麻醉剂传感的单金属到三金属纳米团簇工程学
Shashikana Paria,Nijeshree Nayak,Prasenjit Maity
Shashikana Paria
Monometallic, bimetallic, and trimetallic fluorescent nanoclusters (NCs) stabilized by lysozyme (Lyz), glutathione (GSH), and 4-mercaptopropionic acid (MPA) were synthesized using gold (Au), silver (Ag), and cadmium (Cd) via a simple chemic...
Hanqing Wu,Shichang Xu,Wenxiu Wu et al.
Hanqing Wu et al.
Copper ions (Cu²⁺) are essential trace elements that play a vital role in maintaining physiological activities, while their homeostasis imbalance is associated with the pathogenesis of various diseases. Therefore, developing a highly sele...
O-acylated/alkylated-modified tetraphenylethene- triphenylamine containing chalcone type AIEgen with solid-state emission properties and cell imaging [0.03%]
含具有固態發光性能的查耳酮類AIEgens的O-酰基/烷基取代四苯乙烯-三芳胺
Kaibo Zheng,Wenlin Wu,Xueer Yang et al.
Kaibo Zheng et al.
Organic solid-state emitters are potential candidates for various optoelectronic and biomedical applications. In this manuscript, four novel O-acylated/alkylated-modified tetraphenylethene-triphenylamine containing chalcone derivatives (TCl...
Computational Density Functional Theory and Kinetic-Thermodynamic Stable Crown-Chair Conformers of Hydroxyphenyl Calix[4]resorcinarene Macrocycles: Molecular Docking, Antioxidant, Antibacterial and Photophysical Applications [0.03%]
基于理论计算的冠状-椅式羟基菲(calix[4]resorcinarene)大环共轭分子对接、抗氧化、抗菌和光物理性质研究
Kasi Sathiyaseelan,Albert Antony Muthu Prabhu
Kasi Sathiyaseelan
This study presents a multi-faceted investigation into the structural, electronic, and therapeutic profiles of the crown and chair conformers of CPRA, 2HPRA, 3HPRA, and 4HPRA macrocycles. A dispersion corrected standard density functional t...
A Fluorescent Probe for Carboxylesterases Detection in Estradiol Valerate-Treated Inflammation Alleviation [0.03%]
一种用于检测雌二醇瓦尔酸治疗下炎症缓解的羧酸酯酶荧光探针
Wenqiang Jiang,Zhenhua Zhong,Lubing Tang et al.
Wenqiang Jiang et al.
In this work, a fluorescent probe PIPM-CE was developed for the carboxylesterases (CE) detection in the estradiol valerate (EV)-treated inflammation alleviation. Under the excitation at 368 nm, the notable fluorescence signal was found at 4...
Synthesis, In Vitro Antimicrobial Assessment, and Molecular Docking Investigations of Some Derived Compounds From Porphyrins [0.03%]
基于卟啉衍生物的合成、体外抗菌评估及分子对接研究
Mondher Dhifet,Bilel Bouzayani,Hayet Edziri et al.
Mondher Dhifet et al.
Porphyrins and their derivatives constitute a class of macrocyclic compounds of major interest in chemistry, biology, and medicine due to their remarkable structural and functional properties. In this work, we describe the synthesis of thre...