Monoclonal antibody-based assay to identify compounds that inhibit Nδ-(5-hydro-4-imidazolon-2-yl)ornithine (G-H1) formation [0.03%]
一种基于单克隆抗体的测定法 可以鉴定抑制Nδ-(5-hydro-4-imidazolon-2-yl)鸟氨酸(M-H1)形成的化合物
Hikari Sugawa,Noriyoshi Manabe,Yoshitaka Hiraoka et al.
Hikari Sugawa et al.
The advanced glycation end-product Nδ-(5-hydro-4-imidazolon-2-yl)ornithine (G-H1) accumulates during the progress of atherosclerosis with type 2 diabetes. Therefore, G-H1 might serve as early diagnostic marker of atherosclerosis, and its i...
Eukaryotic expression and characterization of two α1,2-fucosyltransferase genes in the histo-blood group antigens synthesis pathway of the Pacific oyster (Crassostrea gigas) [0.03%]
太平洋牡蛎( Crassostrea gigas )组织血型抗原合成途径中两种α1,2-岩藻糖转移酶基因的真核表达与鉴定
Junxia Hu,Meng Qu,Weiran Zhang et al.
Junxia Hu et al.
Norovirus (NoV), an important cause of human viral gastroenteritis worldwide, recognizes human histo-blood group antigens (HBGAs) as receptors. Oysters are a vector of foodborne transmission of NoV, and HBGAs have been found in oyster tissu...
Advanced glycation end products (AGEs) and their role in diabetes mellitus and related complications: mechanisms and therapeutic insights [0.03%]
晚期糖基化终末产物(AGE)及其在糖尿病及并发症中的作用:机制和治疗见解
Eskandar Qaed,Waleed Aldahmash,Mueataz A Mahyoub
Eskandar Qaed
Diabetes mellitus (DM) is marked by prolonged elevated blood glucose levels, which lead to the formation of covalent adducts between glucose and plasma proteins through a non-enzymatic reaction called glycation. This biochemical process pla...
Ulises González-González,María Cristina Castañeda-Patlán,María Teresa Hernández-Huerta et al.
Ulises González-González et al.
Cancer remains one of the leading causes of death worldwide. Due to the multiple molecular mechanisms involved in cell transformation, its biology continues to be studied from different perspectives and in other research areas. A hallmark o...
Molecular expression of glycosaminoglycans modifies the plasticity of biphasic mesothelioma in favor of tumor progression [0.03%]
甘露聚糖的分子表达有利于双相型间皮瘤肿瘤进展而非良性发展
Camila Machado Baldavira,Aline Nery Qualiotto,Tabatha Gutierrez Prieto et al.
Camila Machado Baldavira et al.
The study aimed to verify whether the expression of glycosaminoglycans (GAGs) and proteoglycans (PGs) in the tumor matrix affects the plasticity of mesothelioma and its relationship with the phenotype, progression, and resistance to treatme...
Characterization of bacterial glycolipids in Pediococcus pentosaceus for fermented soybean paste (miso) and Tetragenococcus halophilus for soy sauce, in comparison with those in Lactobacillus, Streptococcus and Staphylococcus species [0.03%]
以豆豉和酱油用乳酸菌等细菌糖脂为对象的结构分析研究
Masao Iwamori,Kyoko Tanaka
Masao Iwamori
Gram-positive bacterial biomembranes are composed of phosphatidyl glycerol (PG), cardiolipin (CL), and dihexaosyl diglycerides (DH-DG) as the major lipid constituents. The carbohydrate structures of DH-DG are specific to the particular bact...
Effects of GM1 ganglioside and its derivatives on ETI-rescued F508del-CFTR maturation and host-pathogen interactions in cystic fibrosis bronchial cells [0.03%]
GM1神经节苷脂及其衍生物对囊性纤维化支气管细胞中ETI修复的F508del-CFTR成熟及宿主病原相互作用的影响
Dorina Dobi,Alessandro Rimessi,Nicoletta Loberto et al.
Dorina Dobi et al.
Cystic Fibrosis (CF), a life-threatening hereditary disease, arises from mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, which encodes a chloride-conducting channel widely expressed in epithelial cells. The...
Haoan Sun,Chunbao Xie
Haoan Sun
DDOST is an important subunit of N-glycosylated oligosaccharyltransferase and is closely related to protein N-glycosylation. Some studies have reported that abnormal expression of DDOST is associated with congenital disorders of glycosylati...
Analysis of site-dependent mucins in rat intestinal mucosa using anti-glycan monoclonal antibodies [0.03%]
采用抗糖型单克隆抗体分析大鼠肠粘膜的位点特异性黏蛋白
Makoto Kurihara,Yukinobu Goso,Rei Kawashima et al.
Makoto Kurihara et al.
Intestinal gel-forming mucins are high-molecular weight glycoproteins, and their glycan moieties vary depending on the intestinal site. Although the means of analyzing mucin glycans are limited, monoclonal antibodies are expected to be a po...
Detection of antibodies against the African parasite Trypanosoma brucei using synthetic glycosylphosphatidylinositol oligosaccharide fragments [0.03%]
利用合成糖基磷脂酰肌醇寡糖片段检测非洲锥虫泰萨雷拉布氏鞭毛虫的抗体
Maurice Michel,Benoit Stijlemans,Dana Michel et al.
Maurice Michel et al.