In Silico and in vitro evaluation of Cucurbitaceae seed lectins as promising prophylactic and therapeutic agents against SARS-CoV-2 [0.03%]
基于黄瓜科植物种子凝集素的SARS-CoV-2潜在预防和治疗分子的筛选及评估
Rumana Ahmad,Yusuf Akhter,Varsha et al.
Rumana Ahmad et al.
Concern over COVID-19 has arisen from continuous mutations in SARS-CoV-2 genome leading to emergence of novel variants. A detailed study and understanding of N-linked glycans (NAGs) of SARS-CoV-2 spike protein are key for the development of...
The effects of DPP4 inhibitors, SGLT2 inhibitors and GLP1-RA on the AGE/RAGE pathway: implications for diabetes and its complications [0.03%]
DPP4抑制剂、SGLT2抑制剂和GLP1类似物对AGE/RAGE通路的影响：糖尿病及其并发症的启示
Sajad Abolfazli,Stephen L Atkin,Tannaz Jamialahmadi et al.
Sajad Abolfazli et al.
Asparagine-linked glycosylation protein 1 (ALG1) promotes aggressive phenotypes of lung adenocarcinoma cells, A549, via modulating N-linked glycosylation and ER-Stress [0.03%]
天冬酰胺糖基转移酶1通过调节N-连接的糖基化和内质网压力促进肺腺癌A549细胞的恶性表型
Kanadit Piriyapairoje,Marta Baro,Aanchal Katoch et al.
Kanadit Piriyapairoje et al.
Glycosylation plays a critical role in various biological processes and is essential for cell survival. Aberrant glycosylation has been implicated in numerous diseases, including cancer. Lung cancer remains the leading cause of cancer-relat...
Monoclonal antibody-based assay to identify compounds that inhibit Nδ-(5-hydro-4-imidazolon-2-yl)ornithine (G-H1) formation [0.03%]
一种基于单克隆抗体的测定法 可以鉴定抑制Nδ-(5-hydro-4-imidazolon-2-yl)鸟氨酸(M-H1)形成的化合物
Hikari Sugawa,Noriyoshi Manabe,Yoshitaka Hiraoka et al.
Hikari Sugawa et al.
The advanced glycation end-product Nδ-(5-hydro-4-imidazolon-2-yl)ornithine (G-H1) accumulates during the progress of atherosclerosis with type 2 diabetes. Therefore, G-H1 might serve as early diagnostic marker of atherosclerosis, and its i...
Eukaryotic expression and characterization of two α1,2-fucosyltransferase genes in the histo-blood group antigens synthesis pathway of the Pacific oyster (Crassostrea gigas) [0.03%]
太平洋牡蛎（ Crassostrea gigas ）组织血型抗原合成途径中两种α1，2-岩藻糖转移酶基因的真核表达与鉴定
Junxia Hu,Meng Qu,Weiran Zhang et al.
Junxia Hu et al.
Norovirus (NoV), an important cause of human viral gastroenteritis worldwide, recognizes human histo-blood group antigens (HBGAs) as receptors. Oysters are a vector of foodborne transmission of NoV, and HBGAs have been found in oyster tissu...
Advanced glycation end products (AGEs) and their role in diabetes mellitus and related complications: mechanisms and therapeutic insights [0.03%]
晚期糖基化终末产物（AGE）及其在糖尿病及并发症中的作用：机制和治疗见解
Eskandar Qaed,Waleed Aldahmash,Mueataz A Mahyoub
Eskandar Qaed
Diabetes mellitus (DM) is marked by prolonged elevated blood glucose levels, which lead to the formation of covalent adducts between glucose and plasma proteins through a non-enzymatic reaction called glycation. This biochemical process pla...
Ulises González-González,María Cristina Castañeda-Patlán,María Teresa Hernández-Huerta et al.
Ulises González-González et al.
Cancer remains one of the leading causes of death worldwide. Due to the multiple molecular mechanisms involved in cell transformation, its biology continues to be studied from different perspectives and in other research areas. A hallmark o...
Molecular expression of glycosaminoglycans modifies the plasticity of biphasic mesothelioma in favor of tumor progression [0.03%]
甘露聚糖的分子表达有利于双相型间皮瘤肿瘤进展而非良性发展
Camila Machado Baldavira,Aline Nery Qualiotto,Tabatha Gutierrez Prieto et al.
Camila Machado Baldavira et al.
The study aimed to verify whether the expression of glycosaminoglycans (GAGs) and proteoglycans (PGs) in the tumor matrix affects the plasticity of mesothelioma and its relationship with the phenotype, progression, and resistance to treatme...
Characterization of bacterial glycolipids in Pediococcus pentosaceus for fermented soybean paste (miso) and Tetragenococcus halophilus for soy sauce, in comparison with those in Lactobacillus, Streptococcus and Staphylococcus species [0.03%]
以豆豉和酱油用乳酸菌等细菌糖脂为对象的结构分析研究
Masao Iwamori,Kyoko Tanaka
Masao Iwamori
Gram-positive bacterial biomembranes are composed of phosphatidyl glycerol (PG), cardiolipin (CL), and dihexaosyl diglycerides (DH-DG) as the major lipid constituents. The carbohydrate structures of DH-DG are specific to the particular bact...
Effects of GM1 ganglioside and its derivatives on ETI-rescued F508del-CFTR maturation and host-pathogen interactions in cystic fibrosis bronchial cells [0.03%]
GM1神经节苷脂及其衍生物对囊性纤维化支气管细胞中ETI修复的F508del-CFTR成熟及宿主病原相互作用的影响
Dorina Dobi,Alessandro Rimessi,Nicoletta Loberto et al.
Dorina Dobi et al.
Cystic Fibrosis (CF), a life-threatening hereditary disease, arises from mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, which encodes a chloride-conducting channel widely expressed in epithelial cells. The...