Review on macrophage polarization during visceral leishmaniasis and impact of glycoprotein [0.03%]
内脏利什曼病中巨噬细胞极化的研究进展及糖蛋白的影响
Nayanika Datta,Sajal Dasmahapatra,Madhusri Pramanik et al.
Nayanika Datta et al.
SPR interaction analysis of GM3 glycan with the integrin α5β1 head domain [0.03%]
GM3糖脂与整合素α5β1头部结构域的表面等离子体共振分析
Shinya Hanashima,Migiwa Kishi,Katsuaki Sasaki et al.
Shinya Hanashima et al.
Integrins are heterodimeric receptors involved in cell adhesion and bidirectional signaling. Ganglioside GM3 in the outer leaflet of cell membranes possibly regulates integrin activity via direct interactions; however, its specific binding ...
Integrating plasma protein-centric multi-omics to evaluate the causal effect of glycosylation on the risk of cancer [0.03%]
整合血浆蛋白中心多组学以评估糖基化对癌症风险的因果关系
Zhi Geng,Kangwei Qi,Long Yu et al.
Zhi Geng et al.
Glycosylation is a crucial post-translational modification, and numerous studies have reported its significant role in cancer progression. Nevertheless, no study has comprehensively analyzed the causal effect of glycosylation on the risk of...
Assessment of IgG N-Glycan patterns in adult patients with immune thrombocytopenia and healthy individuals [0.03%]
免疫性血小板减少症成人患者与健康人群IgG糖型谱的评估研究
Ena Ranković,Natali Nakić Bedeković,Frano Vučković et al.
Ena Ranković et al.
Mass spectrometric profiling reveals alterations in N-Glycans and O-Glycans in Tay-Sachs disease under Autophagy-Induced conditions [0.03%]
基于自噬诱导条件下的泰萨克斯病患者N-糖链和O-糖链的质谱分析
Melike Can,Hande Basirli,Chunsheng Jin et al.
Melike Can et al.
Tay-Sachs disease is a rare neurodegenerative disorder caused by mutations in the HEXA gene. The HEXA gene encodes the α-subunit of the enzyme β-hexosaminidase A, which degrades GM2 ganglioside. Previously, we identified impaired autophag...
High molecular weight fucosylated glycosaminoglycan promotes the binding of antithrombin and thrombin: a template mechanism and structure-activity relationship study [0.03%]
高分子量岩藻糖基化糖胺聚糖促进抗凝血酶与凝血酶结合：模板机制及构效关系研究
Chuang Xiao,Li Xu,Ying Cai et al.
Chuang Xiao et al.
Native fucosylated glycosaminoglycan (FG), a structurally unique polysaccharide with chondroitin sulfate like backbone and sulfated fucose side chains, has multiple anticoagulant mechanisms. Analyzing the interaction between FG and coagulat...
Identification of a distinct sialic acid (KDN) and a KDN-specific aldolase in Pacific oyster [0.03%]
太平洋牡蛎中岩藻糖基化神经节苷脂分子的鉴定及其特异性丙酮酸羧化酶的克隆与功能分析
Zi-Xuan Hu,Jia-Yu Zhang,Jitske van Ede et al.
Zi-Xuan Hu et al.
Sialic acids are a diverse family of acidic sugars typically found at the terminal positions of glycan chains, mediating key physiological and pathological processes across animals - particularly vertebrates - including cell signaling and h...
In Silico and in vitro evaluation of Cucurbitaceae seed lectins as promising prophylactic and therapeutic agents against SARS-CoV-2 [0.03%]
基于黄瓜科植物种子凝集素的SARS-CoV-2潜在预防和治疗分子的筛选及评估
Rumana Ahmad,Yusuf Akhter,Varsha et al.
Rumana Ahmad et al.
Concern over COVID-19 has arisen from continuous mutations in SARS-CoV-2 genome leading to emergence of novel variants. A detailed study and understanding of N-linked glycans (NAGs) of SARS-CoV-2 spike protein are key for the development of...
The effects of DPP4 inhibitors, SGLT2 inhibitors and GLP1-RA on the AGE/RAGE pathway: implications for diabetes and its complications [0.03%]
DPP4抑制剂、SGLT2抑制剂和GLP1类似物对AGE/RAGE通路的影响：糖尿病及其并发症的启示
Sajad Abolfazli,Stephen L Atkin,Tannaz Jamialahmadi et al.
Sajad Abolfazli et al.
Asparagine-linked glycosylation protein 1 (ALG1) promotes aggressive phenotypes of lung adenocarcinoma cells, A549, via modulating N-linked glycosylation and ER-Stress [0.03%]
天冬酰胺糖基转移酶1通过调节N-连接的糖基化和内质网压力促进肺腺癌A549细胞的恶性表型
Kanadit Piriyapairoje,Marta Baro,Aanchal Katoch et al.
Kanadit Piriyapairoje et al.
Glycosylation plays a critical role in various biological processes and is essential for cell survival. Aberrant glycosylation has been implicated in numerous diseases, including cancer. Lung cancer remains the leading cause of cancer-relat...