Adhesion forces in the self-recognition of oligosaccharide epitopes of the proteoglycan aggregation factor of the marine sponge Microciona prolifera [0.03%]
海洋海绵微孔虫(Microciona prolifera)蛋白聚糖聚集因子寡糖表位的自我识别中的粘附力
Adriana Carvalho de Souza,Dragomir N Ganchev,Margot M E Snel et al.
Adriana Carvalho de Souza et al.
Cell aggregation in the marine sponge Microciona prolifera is mediated by a multimillion molecular-mass aggregation factor, termed MAF. Earlier investigations revealed that the cell aggregation activity of MAF depends on two functional doma...
Miwa Takahashi,Toshihide Kobayashi
Miwa Takahashi
Despite a tight regulation of its intracellular content, cholesterol is found accumulated in pathological conditions such as sphingolipidosis as well as after cell treatment with drugs like hydrophobic amines. Furthermore, cellular choleste...
Biochemical characterization of human and murine isoforms of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) [0.03%]
人和鼠UDP-N-乙酰葡萄糖胺-2-差向异构酶/乙酰.manokinase(GNE)同工酶的生化特性分析
Stefan O Reinke,Colin Eidenschink,Chris M Jay et al.
Stefan O Reinke et al.
The bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) is the key enzyme for the biosynthesis of sialic acids, terminal components of glycoconjugates associated with a variety of physiological and patho...
Endothelial cell-laminin interaction: modulation of LDH expression involves alpha6beta4 integrin-FAK-p38MAPK pathway [0.03%]
内皮细胞层粘连蛋白的作用:LDH表达的调节涉及alpha6beta4整合素-FAK-p38MAPK途径
P R Sudhakaran,R I Viji,M S Kiran et al.
P R Sudhakaran et al.
One of the possible mechanisms of the angiogenic effect of laminin (Ln) involves modulation of the biological activity of VEGF by regulating poly ADP ribosylation (PAR). PAR modification of VEGF was found to be related with the changes in N...
Functional characterization of an eosinophil-specific galectin, ovine galectin-14 [0.03%]
绵羊嗜酸性粒细胞特异性半乳糖凝集素的分子克隆与功能表征:绵羊galectin-14
Anna R Young,Garry J Barcham,Joanna M Kemp et al.
Anna R Young et al.
Across mammalian species, human galectin-10 and ovine galectin-14 are unique in their expression in eosinophils and their release into lung and gastrointestinal tissues following allergen or parasite challenge. Recombinant galectin-14 is ac...
Glycosylation of human fetal mucins: a similar repertoire of O-glycans along the intestinal tract [0.03%]
人胎盘黏蛋白的糖基化:肠道全长O-连接聚糖类似组合
Catherine Robbe-Masselot,Emmanuel Maes,Monique Rousset et al.
Catherine Robbe-Masselot et al.
Intestinal mucins are very high molecular weight glycoproteins secreted by goblet cells lining the crypt and the surface of the colonic mucosa. Profound alterations of mucin O-glycans are observed in diseases such as cancer and inflammation...
Effect of capsaicin on ligand binding activity of the hippocampal serotonin1A receptor [0.03%]
辣椒素对海马5-HT1A受体配体结合活性的影响
Rajesh Prasad,Pushpendra Singh,Amitabha Chattopadhyay
Rajesh Prasad
The serotonin(1A) receptor is an important member of the G-protein coupled receptor family, and is involved in the generation and modulation of a variety of cognitive, behavioral, and developmental functions. In order to examine the role of...
Complete primary structure of a newly characterized galactose-specific lectin from the seeds of Dolichos lablab [0.03%]
完整的刀豆属植物菜豆凝集素Ⅰ型糖蛋白氨基酸序列及结构分析
Nagender Rao Rameshwaram,Narasimha Kumar Karanam,Christian Scharf et al.
Nagender Rao Rameshwaram et al.
A new unique lectin (galactose-specific) purified from the seeds of Dolichos lablab, designated as DLL-II is a heterodimer composed of closely related subunits alpha and beta. These were separated by SDS-PAGE and isolated by electroelution....
Comparative Study
Glycoconjugate journal. 2009 Feb;26(2):161-72. DOI:10.1007/s10719-008-9173-1 2009
Brain lipid composition in grey-lethal mutant mouse characterized by severe malignant osteopetrosis [0.03%]
重度恶性骨纤维硬化症灰死亡突变小鼠脑脂质组成特征分析
Alessandro Prinetti,Federica Rocchetta,Elvira Costantino et al.
Alessandro Prinetti et al.
The grey-lethal mouse (gl/gl) mutant most closely resembles the severe human malignant autosomal recessive OSTM1-dependent form of osteopetrosis that it has been described to be associated with neurological abnormalities. For this reason, w...
Structural characterization of glycosaminoglycans from zebrafish in different ages [0.03%]
不同生长阶段斑马鱼糖胺聚糖的结构特征分析
Fuming Zhang,Zhenqing Zhang,Robert Thistle et al.
Fuming Zhang et al.
The zebrafish (Danio rerio) is a popular model organism for the study of developmental biology, disease mechanisms, and drug discovery. Glycosaminoglycans (GAGs), located on animal cell membranes and in the extracellular matrix, are importa...