Serum biomarker discovery related to pathogenesis in acute coronary syndrome by proteomic approach [0.03%]
蛋白质组学方法在急性冠脉综合征发病机制相关的血清生物标记物发现中的应用
Miji Shin,Sora Mun,Sang Hyun Park et al.
Miji Shin et al.
Acute coronary syndrome (ACS) results from inadequate supply of blood flow from the coronary arteries to the heart or ischemia. ACS has an extremely high morbidity and mortality. The levels of biomarkers currently used for detection of ACS ...
Traditional Chinese medicine Bu-Shen-Jian-Pi-Fang attenuates glycolysis and immune escape in clear cell renal cell carcinoma: results based on network pharmacology [0.03%]
补肾健脾方通过抑制糖酵解和免疫逃逸改善透明细胞肾细胞癌：基于网络药理学结果分析
Jinzhou Zheng,Wenhao Xu,Wangrui Liu et al.
Jinzhou Zheng et al.
Clear cell renal cell carcinoma (ccRCC) is the most common malignant type of kidney cancer. The present study aims to explore the underlying mechanism and potential targets of the traditional Chinese medicine Bu-Shen-Jian-Pi-Fang (BSJPF) in...
Fajuan Cheng,Bin Zheng,Jianwei Wang et al.
Fajuan Cheng et al.
Histone deacetylase (HDAC) 10, a class II family, has been implicated in various tumors and non-tumor diseases, which makes the discovery of biological functions and novel inhibitors a fundamental endeavor. In cancers, HDAC10 plays crucial ...
Identification and validation of ADME genes as prognosis and therapy markers for hepatocellular carcinoma patients [0.03%]
肝细胞癌的ADME基因鉴定及验证其作为预后和治疗标志物的价值
Jukun Wang,Ke Han,Chao Zhang et al.
Jukun Wang et al.
Purpose: ADME genes are genes involved in drug absorption, distribution, metabolism, and excretion (ADME). Previous studies report that expression levels of ADME-related genes correlate with prognosis of hepatocellular ca...
Construction of a prognostic model for non-small-cell lung cancer based on ferroptosis-related genes [0.03%]
基于铁死亡相关基因的非小细胞肺癌预后模型的构建
Ke Han,Jukun Wang,Kun Qian et al.
Ke Han et al.
We wished to construct a prognostic model based on ferroptosis-related genes and to simultaneously evaluate the performance of the prognostic model and analyze differences between high-risk and low-risk groups at all levels. The gene-expres...
Targeted next-generation sequencing identifies ABCA4 mutations in Chinese families with childhood-onset and adult-onset Stargardt disease [0.03%]
目标序列下一代测序法识别出的中国青少年和成人视网膜色素上皮衍生因子Stargardt病突变型ABCA4
Ling-Hui Qu,Xin Jin,Chao Zeng et al.
Ling-Hui Qu et al.
Background: Stargardt disease (STGD) is the most common form of juvenile macular dystrophy associated with progressive central vision loss, and is agenetically and clinically heterogeneous disease. Molecular diagnosis is ...
Identification of potential core genes and pathways predicting pathogenesis in head and neck squamous cell carcinoma [0.03%]
头颈鳞状细胞癌致病潜能核心基因和通路的鉴定
Mengmeng Wang,Bin Zhong,Man Li et al.
Mengmeng Wang et al.
Head and neck squamous cell carcinoma (HNSCC) is the most common subtype of head and neck cancer; however, its pathogenesis and potential therapeutic targets remain largely unknown. In the present study, we analyzed three gene expression pr...