Integrated bioinformatics analysis revealed the regulation of angiogenesis by tumor cells in hepatocellular carcinoma [0.03%]
整合生物信息学分析揭示肝细胞癌肿瘤细胞调控血管生成的机制
Meisi Huo,Kangkang Yu,Yahui Zheng et al.
Meisi Huo et al.
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer mortality, metastasis accounts for most of the cases. Angiogenesis plays an important role in cancer metastasis, but how tumor cells affect the function of endothelial ce...
The positive rates of hepatitis B surface antibody in youth after booster vaccination: a 4-year follow-up study with large sample [0.03%]
乙肝表面抗体阳性的青年人接种乙肝疫苗后四年随访研究（大规模样本）
Xia Zhu,Juan Wang,Ming Wang et al.
Xia Zhu et al.
Background: Hepatitis B virus (HBV) infection is still a public issue in the world. Hepatitis B vaccination is widely used as an effective measure to prevent HBV infection. This large-sample study aimed to evaluate the po...
Evaluation of anticancer effects of Juniperus communis extract on hepatocellular carcinoma cells in vitro and in vivo [0.03%]
评估Juniperus communis提取物对体内外肝癌细胞的抗癌作用
Nan-Chieh Huang,Ru-Lai Huang,Xiao-Fan Huang et al.
Nan-Chieh Huang et al.
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and accounts for the fourth leading cause of all cancer deaths. Scientific evidence has found that plant extracts seem to be a reliable choice due to their multi...
Serum HBV pregenomic RNA exhibited opposite associations with NKdim and NKbright cell immunity in treatment-naïve chronic hepatitis B patients [0.03%]
慢性乙肝患者外周血HBV前基因组RNA与NK细胞免疫之间的关系
Yurong Gu,Zexuan Huang,Xiaoyan Li et al.
Yurong Gu et al.
Hepatitis B virus (HBV) pregenomic RNA (pgRNA) is a new biomarker that reflects HBV replication, but its relationship with natural killer (NK) cell immunity in chronic hepatitis B (CHB) is unknown. We assessed serum HBV pgRNA levels in 323 ...
Association of the polymorphism of the vitamin D receptor gene (VDR) with the risk of leprosy in the Brazilian Amazon [0.03%]
巴西亚马逊地区维生素D受体基因多态性与汉森病易感性的相关性研究
Jasna Letícia Pinto Paz,Maria do Perpétuo Socorro Corrêa Amador Silvestre,Letícia Siqueira Moura et al.
Jasna Letícia Pinto Paz et al.
The transmission and evolution of leprosy depends on several aspects, including immunological and genetic factors of the host, as well as genetic factors of Mycobacterium leprae. The present study evaluated the association of single nucleot...
Conditioned medium of IGF1-induced synovial membrane mesenchymal stem cells increases chondrogenic and chondroprotective markers in chondrocyte inflammation [0.03%]
IGF1诱导的滑膜间充质干细胞培养液增加软骨细胞炎症中的软骨生成和软骨保护标志物
Marlina Marlina,Rizki Rahmadian,Armenia Armenia et al.
Marlina Marlina et al.
Recently, mesenchymal stem cells (MSCs) have been the most explored cells for cell therapy for osteoarthritis (OA) that can be obtained from various sources. Synovial membrane MSCs (SMMSCs) provide best potential for OA therapy, however the...
Construction of a five-gene prognostic model based on immune-related genes for the prediction of survival in pancreatic cancer [0.03%]
基于免疫相关基因的五基因预后模型在胰腺癌患者生存预测中的作用
Bo Liu,Tingting Fu,Ping He et al.
Bo Liu et al.
Purpose: To identify differentially expressed immune-related genes (DEIRGs) and construct a model with survival-related DEIRGs for evaluating the prognosis of patients with pancreatic cancer (PC). ...
Ruijing Tang,Shang Yang,Georg Nagel et al.
Ruijing Tang et al.
Protein purification is the vital basis to study the function, structure and interaction of proteins. Widely used methods are affinity chromatography-based purifications, which require different chromatography columns and harsh conditions, ...
Glucose regulates expression of pro-inflammatory genes, IL-1β and IL-12, through a mechanism involving hexosamine biosynthesis pathway-dependent regulation of α-E catenin [0.03%]
葡萄糖通过己糖胺生物合成途径依赖性调节α-E-catenin机制来调控促炎基因IL-1β和IL-12的表达
Waruni C Dissanayake,Jin Kyo Oh,Brie Sorrenson et al.
Waruni C Dissanayake et al.
High glucose levels are associated with changes in macrophage polarisation and evidence indicates that the sustained or even short-term high glucose levels modulate inflammatory responses in macrophages. However, the mechanism by which macr...
Monocyte-to-albumin ratio as a novel predictor of long-term adverse outcomes in patients after percutaneous coronary intervention [0.03%]
单核细胞与白蛋白比率可作为经皮冠状动脉介入术后长期预后的新型预测指标
Zeng-Lei Zhang,Qian-Qian Guo,Jun-Nan Tang et al.
Zeng-Lei Zhang et al.
Background: Monocyte count and serum albumin (Alb) have been proven to be involved in the process of systemic inflammation. Therefore, we investigated the prognostic value of monocyte-to-albumin ratio (MAR) in patients wh...