The anti-tumor effects of the combination of microwave hyperthermia and lobaplatin against breast cancer cells in vitro and in vivo [0.03%]
微波热疗联合洛铂对乳腺癌细胞的体内、外增效抗肿瘤作用
Xiaohu Li,Xin Zhang,Inam Ullah Khan et al.
Xiaohu Li et al.
Background: Breast cancer is the main lethal disease among females. The combination of lobaplatin and microwave hyperthermia plays a crucial role in several kinds of cancer in the clinic, but its possible mechanism in bre...
A microfluidic array device for single cell capture and intracellular Ca2+ response analysis induced by dynamic biochemical stimulus [0.03%]
一种用于单细胞捕获及生化刺激下细胞内钙离子响应分析的芯片实验室装置
Wenbo Wei,Miao Zhang,Zhongyuan Xu et al.
Wenbo Wei et al.
A microfluidic array was constructed for trapping single cell and loading identical dynamic biochemical stimulation for gain a better understanding of Ca2+ signaling at single cell resolution in the present study. This microfluidic array co...
FOXD1 expression in head and neck squamous carcinoma: a study based on TCGA, GEO and meta-analysis [0.03%]
TCGA、GEO和meta分析为基础的头颈部鳞状细胞癌中的FOXD1表达研究
Junjie Huang,Bin Liang,Tianjiao Wang
Junjie Huang
Forkhead box D1 (FOXD1) is a new member of FOX transcription factor family. FOXD1 has demonstrated multilevel roles during normal development, and several diseases' pathogenesis. However, little is known about the role of FOXD1 in the progr...
Meta-Analysis
Bioscience reports. 2021 Jul 30;41(7):BSR20210158. DOI:10.1042/BSR20210158 2021
Multiple roles of haem in cystathionine β-synthase activity: implications for hemin and other therapies of acute hepatic porphyria [0.03%]
血红素在胱硫醚-β-合成酶活性中的多种作用：对于急性肝紫质病的亚铁血红素和其他疗法的意义
Abdulla A-B Badawy
Abdulla A-B Badawy
The role of haem in the activity of cystathionine β-synthase (CBS) is reviewed and a hypothesis postulating multiple effects of haem on enzyme activity under conditions of haem excess or deficiency is proposed, with implications for some t...
Li-Mei Chen,Julius C Chai,Bin Liu et al.
Li-Mei Chen et al.
The serine protease prostasin is a negative regulator of lipopolysaccharide-induced inflammation and has a role in the regulation of cellular immunity. Prostasin expression in cancer cells inhibits migration and metastasis, and reduces epit...
Biological implications of genetic variations in autism spectrum disorders from genomics studies [0.03%]
基因组学研究揭示的自闭症遗传变异的生物学意义
Yue Zhang,Xuanshi Liu,Ruolan Guo et al.
Yue Zhang et al.
Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental condition characterized by atypical social interaction and communication together with repetitive behaviors and restricted interests. The prevalence of ASD has been...
Recent advancements in the exploitation of the gut microbiome in the diagnosis and treatment of colorectal cancer [0.03%]
最近利用肠道微生物组在结直肠癌诊断和治疗方面取得的进展
Katie J Stott,Bethan Phillips,Lee Parry et al.
Katie J Stott et al.
Over the last few decades it has been established that the complex interaction between the host and the multitude of organisms that compose the intestinal microbiota plays an important role in human metabolic health and disease. Whilst ther...
Themistoklis Paraschiakos,Wilhelm Flat,Ya Chen et al.
Themistoklis Paraschiakos et al.
Overexpression of the neuronal InsP3kinase-A increases malignancy of different tumor types. Since InsP3kinase-A highly selectively binds Ins(1,4,5)P3, small molecules competing with Ins(1,4,5)P3 provide a promising approach for the therapeu...
Clinicopathological and prognostic significance of LINC00673 in human malignancy: a review and meta-analysis [0.03%]
长链非编码RNA LINC00673在人类恶性肿瘤中的临床病理及预后意义：综述与meta分析研究
Yurong Zhu,Zhifa Zhang,Hui Peng et al.
Yurong Zhu et al.
Background: We conducted this research to investigate the relationship between long intergenic non-protein coding RNA 673 (linc00673) expression and prognosis and clinicopathological parameters in human malignancies. ...
Meta-Analysis
Bioscience reports. 2021 Jul 30;41(7):BSR20211175. DOI:10.1042/BSR20211175 2021
Function of cofactor Akirin2 in the regulation of gene expression in model human Caucasian neutrophil-like HL60 cells [0.03%]
乙酰辅因子Akirin2在人白细胞白血病类中性粒细胞HL-60中的功能研究
Sara Artigas-Jerónimo,Margarita Villar,Agustín Estrada-Peña et al.
Sara Artigas-Jerónimo et al.
The Akirin family of transcription cofactors are involved throughout the metazoan in the regulation of different biological processes such as immunity, interdigital regression, muscle and neural development. Akirin do not have catalytic or ...