Identification of hub genes in colorectal cancer based on weighted gene co-expression network analysis and clinical data from The Cancer Genome Atlas [0.03%]
基于加权基因共表达网络分析和来自肿瘤基因组图谱的临床数据识别结直肠癌中的枢纽基因
Yu Zhang,Jia Luo,Zhe Liu et al.
Yu Zhang et al.
Colorectal cancer (CRC) is one of the most common tumors worldwide and is associated with high mortality. Here we performed bioinformatics analysis, which we validated using immunohistochemistry in order to search for hub genes that might s...
Membrane interaction and disulphide-bridge formation in the unconventional secretion of Tau [0.03%]
Tau通过非常规分泌途径释放时的膜相互作用与二硫键形成
Marianna Hellén,Arnab Bhattacharjee,Riikka-Liisa Uronen et al.
Marianna Hellén et al.
Misfolded, pathological tau protein propagates from cell to cell causing neuronal degeneration in Alzheimer's disease and other tauopathies. The molecular mechanisms of this process have remained elusive. Unconventional secretion of tau tak...
Microarray analysis of genes with differential expression of m6A methylation in lung cancer [0.03%]
肺癌中m6A甲基化差异表达基因的微阵列分析
Shuo Wu,Xing Lv,Yan Zhang et al.
Shuo Wu et al.
Purpose: N6-methyladenosine (m6A) is among the most abundant mRNA modifications in eukaryote. The aim of the present study was to investigate function of m6A mRNA methylation in lung cancer and the underlying mechanism. ...
Function of cofactor Akirin2 in the regulation of gene expression in model human Caucasian neutrophil-like HL60 cells [0.03%]
乙酰半胱氨酸2在人类白细胞HL-60中调节基因表达的功能研究
Sara Artigas-Jerónimo,Margarita Villar,Agustín Estrada-Peña et al.
Sara Artigas-Jerónimo et al.
The Akirin family of transcription cofactors are involved throughout the metazoan in the regulation of different biological processes (BPs) such as immunity, interdigital regression, muscle and neural development. Akirin do not have catalyt...
Rajesh Ahirwar,Sonu Gandhi,Komal Komal et al.
Rajesh Ahirwar et al.
Coronavirus disease 2019 (COVID-19) is a life-threatening respiratory infection caused by severe acute respiratory syndrome virus (SARS-CoV-2), a novel human coronavirus. COVID-19 was declared a pandemic by World Health Organization in Marc...
Redox index of Cys-thiol residues of serum apolipoprotein E and its diagnostic potential [0.03%]
血清载脂蛋白E半胱氨酸残基的氧化还原指数及其诊断潜力
Kazuyoshi Yamauchi,Chiaki Taira,Yasushi Kawakami
Kazuyoshi Yamauchi
Background: The redox modulation of Cys-thiol participates in various pathophysiological processes. We explored the proper index for estimating the redox status of Cys-thiol of serum apolipoprotein E (apoE), named "redox-...
Prognostic significance of the systemic immune-inflammation index in pancreatic carcinoma patients: a meta-analysis [0.03%]
系统免疫炎症指数在胰腺癌患者中的预后价值：一项meta分析研究
Xiaocheng Li,Huapeng Lin,Renbin Ouyang et al.
Xiaocheng Li et al.
Background: Systemic immune-inflammation index (SII) is a prognostic indicator for several malignancies, including pancreatic carcinoma; however, there is no consensus on its significance. In the current study, a systemat...
Meta-Analysis
Bioscience reports. 2021 Aug 27;41(8):BSR20204401. DOI:10.1042/BSR20204401 2021
Exploration of the molecular targets and mechanisms of suxiao xintong dropping pills for myocardial infarction by network pharmacology method [0.03%]
基于网络药理学方法的心血宁滴丸治疗心肌梗死作用分子靶点及机制探讨
Daqiu Chen,Yanqing Wu,Yixing Chen et al.
Daqiu Chen et al.
Background: Suxiao Xintong dropping pills (SXXTDP), a traditional Chinese medicine, is widely applied for treating myocardial infarction (MI). However, its therapy mechanisms are still unclear. Therefore, this research is...
Prognostic value of neuron-specific enolase in patients with advanced and metastatic non-neuroendocrine non-small cell lung cancer [0.03%]
神经元特异性烯醇化酶对晚期和转移性非神经内分泌非小细胞肺癌患者的预后价值
Peng Yan,Yiming Han,Anna Tong et al.
Peng Yan et al.
Background: Increased serum neuron-specific enolase (NSE) level was found in a substantial proportion (30-69%) of patients with non-small-cell lung cancer (NSCLC), but little was known about the clinical properties of NSE...
Full-length transcriptome assembly of andrias davidianus (amphibia: caudata) skin via hybrid sequencing [0.03%]
斑鳖皮肤全转录组组装
Yu Bai,Yonglu Meng,Jianlin Luo et al.
Yu Bai et al.
The Chinese giant salamander, Andrias davidianus, is the largest amphibian species in the world; it is thus an economically and ecologically important species. The skin of A. davidianus exhibits complex adaptive structural and functional ad...