miR-219-5p targets TBXT and inhibits breast cancer cell EMT and cell migration and invasion [0.03%]
mir-219-5p作用于TBXT抑制乳腺癌细胞上皮间质转化及迁移侵袭能力
Qin Ye,Xing Wang,Mei Yuan et al.
Qin Ye et al.
miR-219-5p has been reported to act as either a tumor suppressor or a tumor promoter in different cancers by targeting different genes. In the present study, we demonstrated that miR-219-5p negatively regulated the expression of TBXT, a kno...
Correction: LncRNA HOTAIR contributes Taxol-resistance of hepatocellular carcinoma cells via activating AKT phosphorylation by down-regulating miR-34a [0.03%]
订正：长链非编码RNAHOTAIR通过下调miR-34a来激活AKT磷酸化从而促进肝癌细胞对紫杉醇的抗性
Published Erratum
Bioscience reports. 2021 Aug 27;41(8):BSR-2020-1627_COR. DOI:10.1042/BSR-2020-1627_COR 2021
Butyryl/Caproyl-CoA:Acetate CoA-transferase: cloning, expression and characterization of the key enzyme involved in medium-chain fatty acid biosynthesis [0.03%]
丁酰/己酰-CoA：乙酸-CoA转移酶：中链脂肪酸生物合成的关键酶的克隆、表达和表征
Qingzhuoma Yang,Shengtao Guo,Qi Lu et al.
Qingzhuoma Yang et al.
Coenzyme A transferases (CoATs) are important enzymes involved in carbon chain elongation, contributing to medium-chain fatty acid (MCFA) biosynthesis. For example, butyryl-CoA:acetate CoA transferase (BCoAT) is responsible for the final st...
SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microclot formation in COVID-19 [0.03%]
SARS-CoV-2刺突蛋白S1诱导抗纤溶纤维蛋白（原）的形成：在COVID-19患者中形成微凝块的意义
Lize M Grobbelaar,Chantelle Venter,Mare Vlok et al.
Lize M Grobbelaar et al.
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2)-induced infection, the cause of coronavirus disease 2019 (COVID-19), is characterized by unprecedented clinical pathologies. One of the most important pathologies, is hypercoagula...
Targeting the 'garbage-bin' to fight cancer: HDAC6 inhibitor WT161 has an anti-tumor effect on osteosarcoma and synergistically interacts with 5-FU [0.03%]
“靶向‘垃圾站’抗癌：HDAC6抑制剂WT161对骨肉瘤具有抗肿瘤作用并与5-氟尿嘧啶产生协同效应
Consolato M Sergi
Consolato M Sergi
An imbalance between protein aggregation and protein degradation may induce 'stress' in the functionality of the endoplasmic reticulum (ER). There are quality control (QC) mechanisms to minimize misfolding and to eliminate misfolded protein...
Retraction: MicroRNA-506 inhibits rheumatoid arthritis fibroblast-like synoviocytes proliferation and induces apoptosis by targeting TLR4 [0.03%]
撤稿：MicroRNA-506通过靶向TLR4抑制类风湿性关节炎滑膜成纤维细胞增殖并诱导凋亡
Retraction of Publication
Bioscience reports. 2021 Jul 30;41(7):BSR-2018-2500_RET. DOI:10.1042/BSR-2018-2500_RET 2021
MicroRNAs targeting VEGF are related to vascular dysfunction in preeclampsia [0.03%]
针对VEGF的微小核糖核酸与子痫前期血管功能障碍有关
Isabel Witvrouwen,Dominique Mannaerts,Jessica Ratajczak et al.
Isabel Witvrouwen et al.
In preeclampsia (PE), pre-existent maternal endothelial dysfunction leads to impaired placentation and vascular maladaptation. The vascular endothelial growth factor (VEGF) pathway is essential in the placentation process and VEGF expressio...
Kourosh H Ebrahimi,James S O McCullagh
Kourosh H Ebrahimi
The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which started in late 2019, has caused huge social and economic losses. A growing number of investigators are focusing on understanding the interaction of ...
Identification of hub genes in colorectal cancer based on weighted gene co-expression network analysis and clinical data from The Cancer Genome Atlas [0.03%]
基于加权基因共表达网络分析和来自肿瘤基因组图谱的临床数据识别结直肠癌中的枢纽基因
Yu Zhang,Jia Luo,Zhe Liu et al.
Yu Zhang et al.
Colorectal cancer (CRC) is one of the most common tumors worldwide and is associated with high mortality. Here we performed bioinformatics analysis, which we validated using immunohistochemistry in order to search for hub genes that might s...