Commentary on "Urinary L-erythro-β-hydroxyasparagine - a novel serine racemase inhibitor and substrate of the Zn2+-dependent D-serine dehydratase" [0.03%]
《“尿L-赤藓糖醇-β-羟基天冬酰胺 – 一种新颖的丝氨酸消旋酶抑制剂和Zn2+-依赖性的D-丝氨酸脱水酶底物”一文的评论》
Fabio Kendi Tamaki
Fabio Kendi Tamaki
The analysis of the urine contents can be informative of physiological homeostasis, and it has been speculated that the levels of urinary D-serine (D-ser) could inform about neurological and renal disorders. By analysing the levels of urina...
Bioinformatics analysis of tumor-educated platelet microRNAs in patients with hepatocellular carcinoma [0.03%]
肝细胞癌患者肿瘤教育血小板microRNA的生物信息学分析
Beibei Zhu,Shanshan Gu,Xiaoting Wu et al.
Beibei Zhu et al.
Background: Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies that seriously threaten global health. The primary reason for its grim prognosis is the lack of sensitive tools for early diagnosis. The...
Computational study, synthesis and evaluation of active peptides derived from Parasporin-2 and spike protein from Alphacoronavirus against colorectal cancer cells [0.03%]
来自Parasporin-2和阿尔法冠状病毒刺突蛋白的活性多肽在结肠癌细胞中的计算研究，合成及其评估
Jenniffer Cruz,Miguel Orlando Suárez-Barrera,Paola Rondón-Villarreal et al.
Jenniffer Cruz et al.
Parasporin-2Aa1 (PS2Aa1) is a toxic protein of 37 KDa (30 kDa, activated form produced by proteolysis) that was shown to be cytotoxic against specific human cancer cells, although its mechanism of action has not been elucidated yet. In orde...
Cell3: A new vision for study of the endomembrane system in mammalian cells [0.03%]
细胞3：对哺乳动物细胞内膜系统的研究的新视角
Margaritha M Mysior,Jeremy C Simpson
Margaritha M Mysior
The endomembrane system of mammalian cells provides massive capacity for the segregation of biochemical reactions into discrete locations. The individual organelles of the endomembrane system also require the ability to precisely transport ...
ZNF76 predicts prognosis and response to platinum chemotherapy in human ovarian cancer [0.03%]
锌指蛋白76预测人类卵巢癌的预后和铂类化疗反应
Tian Hua,Rui-Min Wang,Xiao-Chong Zhang et al.
Tian Hua et al.
Ovarian cancer (OV) is the most lethal gynecologic malignancy. One major reason of the high mortality of the disease is due to platinum-based chemotherapy resistance. Increasing evidence reveal the important biological functions and clinica...
Real-time kinetic studies of Mycobacterium tuberculosis LexA-DNA interaction [0.03%]
结核分枝杆菌LexA-DNA相互作用的实时动力学研究
Chitral Chatterjee,Soneya Majumdar,Sachin Deshpande et al.
Chitral Chatterjee et al.
Transcriptional repressor, LexA, regulates the 'SOS' response, an indispensable bacterial DNA damage repair machinery. Compared with its Escherichia coli ortholog, LexA from Mycobacterium tuberculosis (Mtb) possesses a unique N-terminal ext...
Stimulation of the Runx2 P1 promoter by collagen-derived dipeptide prolyl-hydroxyproline bound to Foxg1 and Foxo1 in osteoblasts [0.03%]
胶原衍生的二肽脯氨酰-羟脯氨酸结合Foxg1和Foxo1刺激成骨细胞中的Runx2 P1启动子
Kaho Nomura,Yoshifumi Kimira,Yoshihiro Osawa et al.
Kaho Nomura et al.
Collagen-derived dipeptide prolyl-hydroxyproline (Pro-Hyp) directly binds to the forkhead box g1 (Foxg1) protein and causes it to undergo structural alteration. Pro-Hyp also promotes the production of a regulator of osteoblast differentiati...
MiR-34a-3p suppresses pulmonary vascular proliferation in acute pulmonary embolism rat by targeting DUSP1 [0.03%]
MiR-34a-3p通过作用于DUSP1抑制急性肺栓塞大鼠的肺血管增殖
Yang Li,Jinyan Shao,Jianfeng Song et al.
Yang Li et al.
Background: Acute pulmonary embolism (APE) is a prevalent reason of cardiovascular morbidity and mortality. Recent studies have underscored the positive effects of microRNAs (miRNAs) on many diseases. The present study ai...
Pan-cancer analysis of N4-acetylcytidine adaptor THUMPD1 as a predictor for prognosis and immunotherapy [0.03%]
N4-乙酰胞嘧啶接头THUMPD1作为预后和免疫治疗预测因子的泛癌分析
Kuangxun Li,Junzhe Liu,Xinyu Yang et al.
Kuangxun Li et al.
Background: THUMPD1 is a specific RNA adaptor that assists acetylation of mRNA and production of N4-acetylcytidine (ac4C). However, it remains unclear whether THUMPD1 plays a part in tumorigenesis and therapeutic efficacy...
Bioactive Cationic Peptides as Potential Agents for Breast Cancer Treatment [0.03%]
具有生物活性的阳离子肽作为乳腺癌治疗的潜在药物
Marcela Manrique-Moreno,Gloria A Santa-González,Vanessa Gallego
Marcela Manrique-Moreno
Breast cancer continues to affect millions of women worldwide, and the number of new cases dramatically increases every year. The physiological causes behind the disease are still not fully understood. One in every 100 cases can occur in me...