Bioactive cationic peptides as potential agents for breast cancer treatment [0.03%]
具有生物活性的阳离子肽作为治疗乳腺癌的潜在药物
Marcela Manrique-Moreno,Gloria A Santa-González,Vanessa Gallego
Marcela Manrique-Moreno
Breast cancer continues to affect millions of women worldwide, and the number of new cases dramatically increases every year. The physiological causes behind the disease are still not fully understood. One in every 100 cases can occur in me...
Cell3: a new vision for study of the endomembrane system in mammalian cells [0.03%]
细胞3：哺乳动物细胞内膜系统的新型研究视野
Margaritha M Mysior,Jeremy C Simpson
Margaritha M Mysior
The endomembrane system of mammalian cells provides massive capacity for the segregation of biochemical reactions into discrete locations. The individual organelles of the endomembrane system also require the ability to precisely transport ...
Commentary on Urinary l-erythro-β-hydroxyasparagine: a novel serine racemase inhibitor and substrate of the Zn2+-dependent d-serine dehydratase [0.03%]
尿中l-赤藓糖醇-β-羟基天冬胺：新型丝氨酸消旋酶抑制剂及Zn2+依赖的d-丝氨酸脱水酶底物之评论
Fabio K Tamaki
Fabio K Tamaki
The analysis of the urine contents can be informative of physiological homoeostasis, and it has been speculated that the levels of urinary d-serine (d-ser) could inform about neurological and renal disorders. By analysing the levels of urin...
Wendy El Khoury,Zeina Nasr
Wendy El Khoury
The ribosome, the site for protein synthesis, is composed of ribosomal RNAs (rRNAs) and ribosomal proteins (RPs). The latter have been shown to have many ribosomal and extraribosomal functions. RPs are implicated in a variety of pathologica...
Clinical significance and biological functions of chemokine CXCL3 in head and neck squamous cell carcinoma [0.03%]
头颈部鳞状细胞癌中趋化因子CXCL3的临床意义和生物功能
Jian Guan,Jinru Weng,Qiaosheng Ren et al.
Jian Guan et al.
CXCL3 plays extensive roles in tumorigenesis in various types of human cancers through its roles in tumor cell differentiation, invasion, and migration. However, the mechanisms of CXCL3 in head and neck squamous cell carcinoma (HNSCC) remai...
Multiomics profiling of the expression and prognosis of MCMs in endometrial carcinoma [0.03%]
MCM在子宫内膜癌中的表达及预后多组学分析
Hua Lan,Jing Yuan,Xingyu Chen et al.
Hua Lan et al.
Minichromosome maintenance (MCM) family members are a group of genes involved in regulating DNA replication and cell division and have been identified as oncogenes in various cancer types. Several experimental studies have suggested that MC...
Association of m.5178C>A variant with serum lipid levels: a systematic review and meta-analysis [0.03%]
m.5178C>A变异与血清脂质水平的关联性：系统评价和荟萃分析
Fuqiang Liu,Jiyun He,Shengping Wang et al.
Fuqiang Liu et al.
Background: Emerging evidence shows that m.5178C>A variant is associated with a lower risk of coronary artery disease (CAD). However, the specific mechanisms remain elusive. Since dyslipidemia is one of the most critical ...
Meta-Analysis
Bioscience reports. 2021 Dec 22;41(12):BSR20212246. DOI:10.1042/BSR20212246 2021
Commentary on: Screening of immunosuppressive cells from colorectal adenocarcinoma and identification of prognostic markers [0.03%]
评论：筛选结肠腺癌免疫抑制细胞和鉴定预后标记物
Kexin Chen,Zhen Zeng,Chunxiang Ma et al.
Kexin Chen et al.
Colorectal adenocarcinoma (COAD) is one subtype of colorectal carcinoma (CRC), whose development is associated with genetics, inappropriate immune response, and environmental factors. Although significant advances have been made in the trea...
Dopamine signaling impairs ROS modulation by mitochondrial hexokinase in human neural progenitor cells [0.03%]
多巴胺信号使人类神经祖细胞中的线粒体己糖激酶调节ROS的能力受损
Gabriela Assis-de-Lemos,Jamila Monteiro,Viviane M Oliveira-Valença et al.
Gabriela Assis-de-Lemos et al.
Dopamine signaling has numerous roles during brain development. In addition, alterations in dopamine signaling may be also involved in the pathophysiology of psychiatric disorders. Neurodevelopment is modulated in multiple steps by reactive...
LncRNA SNHG6 knockdown inhibits cisplatin resistance and progression of gastric cancer through miR-1297/BCL-2 axis [0.03%]
敲低LncRNA SNHG6通过miR-1297/BCL-2轴抑制胃癌的顺铂抗性和进展
Jiazhan Mei,Guiju Liu,Ruijun Li et al.
Jiazhan Mei et al.
Cisplatin (DDP) resistance is a huge obstacle to gastric cancer (GC) treatment. Long non-coding RNAs (lncRNAs) have been manifested to exert pivotal functions in GC development. Herein, we aimed to explore the functional impact of lncRNA sm...