Diagnostic significance of alanine aminotransferase isoenzymes in alcoholic and non-alcoholic fatty liver cancers [0.03%]
丙氨酸氨基转移酶异构体在酒精性和非酒精性脂肪肝诊断中的意义
Dandan Zhou,Zuowei Yuan,Xiaoqin Shu et al.
Dandan Zhou et al.
Objectives: Alanine aminotransferase (ALT) expression is highly elevated in the serum of patients with hepatocellular carcinoma. However, the role of ALT isoenzymes in the total ALT activity remains unclear. In the presen...
Characterisation and functionalisation of chitosan nanoparticles as carriers for double-stranded RNA (dsRNA) molecules towards sustainable crop protection [0.03%]
壳聚糖纳米颗粒作为双链RNA分子载体的表征及功能化研究以实现可持续作物保护
Dora Scarpin,Luca Nerva,Walter Chitarra et al.
Dora Scarpin et al.
The need to minimise the impact of phytosanitary treatments for disease control boosted researchers to implement techniques with less environmental impact. The development of technologies using molecular mechanisms based on the modulation o...
Branched-chain fatty acids affect the expression of fatty acid synthase and C-reactive protein genes in the hepatocyte cell line [0.03%]
支链脂肪酸影响肝细胞系中脂肪酸合酶和C反应蛋白基因的表达
Paulina Gozdzik,Aleksandra Czumaj,Tomasz Sledzinski et al.
Paulina Gozdzik et al.
Fatty acids (FAs) are known to play an important role in human metabolism; however, still little is known about the functions of certain FA classes present in blood at relatively low concentrations. Examples of such compounds include branch...
Comparative genomics hints at dispensability of multiple essential genes in two Escherichia coli L-form strains [0.03%]
比较基因组学提示两种大肠杆菌L型菌株中多个必需基因的可有性
Yunfei Liu,Yueyue Zhang,Chen Kang et al.
Yunfei Liu et al.
Despite the critical role of bacterial cell walls in maintaining cell shapes, certain environmental stressors can induce the transition of many bacterial species into a wall-deficient state called L-form. Long-term induced Escherichia coli ...
Assessing the dynamics and macromolecular interactions of the intrinsically disordered protein YY1 [0.03%]
评估固有无序蛋白YY1的动力学和大分子相互作用
Heather Donald,Ashleigh Blane,Sindisiwe Buthelezi et al.
Heather Donald et al.
YY1 is a ubiquitously expressed, intrinsically disordered transcription factor involved in neural development. The oligomeric state of YY1 varies depending on the environment. These structural changes may alter its DNA binding ability and h...
Cell organelles are retained inside pyroptotic corpses during inflammatory cell death [0.03%]
炎症细胞死亡过程中细胞器在胞浆内的滞留现象
Anne Hempel,Andrea D&#x;Osualdo,Scott J Snipas et al.
Anne Hempel et al.
Many proinflammatory proteins are released via the necrotic form of cell death known as pyroptosis. Sometimes known as gasdermin D (GSDMD) dependent cell death, pyroptosis results from the formation of pores in the plasma membrane leading t...
Peizhen Lao,Jingyi Chen,Longqian Tang et al.
Peizhen Lao et al.
Pulmonary disease can refer to the disease of the lung itself or the pulmonary manifestations of systemic diseases, which are often connected to the malfunction of the immune system. Regulatory T (Treg) cells have been shown to be important...
GLUT4 dispersal at the plasma membrane of adipocytes: a super-resolved journey [0.03%]
GLUT4在脂肪细胞质膜上的分散：一种超分辨率之旅
Angéline Geiser,Shannan Foylan,Peter W Tinning et al.
Angéline Geiser et al.
In adipose tissue, insulin stimulates glucose uptake by mediating the translocation of GLUT4 from intracellular vesicles to the plasma membrane. In 2010, insulin was revealed to also have a fundamental impact on the spatial distribution of ...
Writers and readers of H3K9me2 form distinct protein networks during the cell cycle that include candidates for H3K9 mimicry [0.03%]
H3K9me2写码蛋白和读码蛋白在细胞周期中形成不同的蛋白质网络并包含H3K9模体假定残基的候选基因
Gareth Pollin,Thiago M De Assuncao,Salomao Doria Jorge et al.
Gareth Pollin et al.
Histone H3 lysine 9 methylation (H3K9me), which is written by the Euchromatic Histone Lysine Methyltransferases EHMT1 and EHMT2 and read by the heterochromatin protein 1 (HP1) chromobox (CBX) protein family, is dysregulated in many types of...